[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100590164":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":20,"locations":30,"responsibleParty":53,"collaborators":10,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":60,"acronym":10,"eligibilityCriteria":61,"healthyVolunteers":58,"sex":62,"minAge":63,"maxAge":10,"enrollmentInfo":64,"targetDuration":10,"studyType":67,"phases":10,"briefSummary":68,"conditions":69,"keywords":72,"overallStatus":33,"whyStopped":10,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"Western Galilee Hospital-Nahariya","OTHER_GOV",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Hemodialysis patients with suspected catheter-related bloodstream infections (CRBSIs).",null,"Study Population:\n\nThe study will include hemodialysis patients over the age of 18 who are hospitalized at the Galilee Medical Center due to sepsis and have provided written informed consent to participate in this study.\n\nStudy Procedure:\n\nDuring hospitalization, and as part of the clinical workup for sepsis, blood cultures will be obtained from three sources:\n\n1. The central venous catheter (CVC),\n2. The dialysis machine circuit, and\n3. A peripheral vein. In addition, parathyroid hormone (PTH) levels will be measured through a blood sample.",[13],"Diagnostic Test: Blood cultures will be obtained from three sources: 1. The central venous catheter (CVC), 2. The dialysis machine circuit, and 3. A peripheral vein",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"DIAGNOSTIC_TEST","Blood cultures will be obtained from three sources: 1. The central venous catheter (CVC), 2. The dialysis machine circuit, and 3. A peripheral vein","PTH levels during sepsis and compare them to baseline pre-infection levels, with serial follow-up of PTH values post-recovery.",[9],[21,26],{"name":22,"role":23,"phone":24,"phoneExt":10,"email":25},"Etty Kruzel-Davila, MD","CONTACT","972-4-9107619","ETTYK@gmc.gov.il",{"name":27,"role":23,"phone":28,"phoneExt":10,"email":29},"Olga Vdovich, MD","972-54-7628542","olgav@gmc.gov.il",[31],{"facility":32,"status":33,"city":34,"state":35,"zip":36,"country":35,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"Galilee Medical Center","RECRUITING","Nahariya","Israel","2210001","IL",{"type":39,"coordinates":40},"Point",[41,42],35.09814,33.00892,{"lat":42,"lon":41},[45,47,49,51],{"name":46,"role":23,"phone":24,"phoneExt":10,"email":25},"Etty Kruzel-Davila, Head of the Nephrology Depart",{"name":27,"role":23,"phone":48,"phoneExt":10,"email":29},"972-4-9107603",{"name":22,"role":50,"phone":10,"phoneExt":10,"email":10},"PRINCIPAL_INVESTIGATOR",{"name":27,"role":52,"phone":10,"phoneExt":10,"email":10},"SUB_INVESTIGATOR",{"type":50,"investigatorFullName":54,"investigatorTitle":55,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Etty Kruzel-Davila","Head of the Nephrology Department","100590164","evaluation-of-microbial-and-endocrinological-parameters-in-dialysis-patients-with-sepsis-100590164",false,"NCT06963853","Evaluation of Microbial and Endocrinological Parameters in Dialysis Patients With Sepsis","Inclusion Criteria: hemodialysis patients over the age of 18 who are hospitalized at the Galilee Medical Center due to sepsis and have provided written informed consent to participate in this study.\n\n\\-\n\nExclusion Criteria: • Patients with cognitive impairment who are unable to provide informed consent.\n\n\\-","ALL","18 Years",{"count":65,"type":66},200,"ESTIMATED","OBSERVATIONAL","This prospective study aims to evaluate the diagnostic value and reliability of blood cultures obtained from different sources-central venous catheter (CVC), dialysis machine, and peripheral vein-in hemodialysis patients with suspected catheter-related bloodstream infections (CRBSIs). By comparing the timing and rates of bacterial growth from each site, the study seeks to identify the most accurate and timely method for diagnosing bloodstream infections in this patient population.\n\nIn addition, the study will assess the dynamics of parathyroid hormone (PTH) levels during acute infections. Specifically, it will investigate whether a significant drop in PTH levels-and the rate of recovery following infection-correlates with adverse outcomes such as infectious complications, cardiovascular morbidity, or 90-day mortality. These findings may offer valuable prognostic insights and support improved monitoring and treatment strategies for dialysis patients experiencing infection.",[70,71],"Sepsis","Hemodialysis",[73,74,75,76,77,78],"blood cultures","parathyroid hormone","catheter","infection","cardiovascular","mortality","2025-05-09",{"date":81,"type":82},"2025-05-14","ACTUAL",{"date":84,"type":82},"2022-08-16",{"date":86,"type":66},"2027-12",{"name":5,"class":6},1]