[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100640792":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":18,"centralContacts":25,"locations":18,"responsibleParty":31,"collaborators":18,"id":33,"slug":34,"hasResults":35,"nctId":36,"briefTitle":37,"officialTitle":38,"acronym":18,"eligibilityCriteria":39,"healthyVolunteers":40,"sex":41,"minAge":42,"maxAge":43,"enrollmentInfo":44,"targetDuration":18,"studyType":47,"phases":48,"briefSummary":50,"conditions":51,"keywords":18,"overallStatus":56,"whyStopped":18,"lastUpdateSubmitDate":57,"lastUpdatePostDateStruct":58,"startDateStruct":61,"completionDateStruct":63,"leadSponsor":65,"locationsCount":18},{"fullName":5,"class":6},"Marmara University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"MIH Restorative Treatment Group","EXPERIMENTAL","Children with molar-incisor hypomineralization (MIH) will receive glass hybrid restorative treatment. Occlusal force distribution and chewing function will be evaluated before and after treatment using digital occlusal analysis and a chewing gum protocol.",[13],"Procedure: Glass Hybrid Restorative Treatment",{"label":15,"type":16,"description":17,"interventionNames":18},"Healthy Control Group","NO_INTERVENTION","Healthy children without MIH will undergo occlusal force distribution and chewing function assessments for comparison with the MIH group. No restorative intervention will be performed.",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"PROCEDURE","Glass Hybrid Restorative Treatment","Restorative treatment of MIH-affected molars using glass hybrid restorative material to evaluate changes in occlusal force distribution and chewing function.",[9],[26],{"name":27,"role":28,"phone":29,"phoneExt":18,"email":30},"Afra Nur Savas","CONTACT","+90 534 327 92 74","aafranursavas@gmail.com",{"type":32,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR","100640792","evaluation-of-occlusal-force-and-masticatory-function-in-children-with-molar-incisor-hypomineralization-100640792",false,"NCT07589179","Evaluation of Occlusal Force and Masticatory Function in Children With Molar-Incisor Hypomineralization","Evaluation of Occlusal Force Distribution and Masticatory Function Before and After Restorative Treatment in Children With Molar-Incisor Hypomineralization","Inclusion Criteria:\n\n* Children aged 7 to 12 years\n* Presence of bilateral molar-incisor hypomineralization (MIH) affecting first permanent molars\n* Need for restorative treatment in MIH-affected molars\n* Cooperative children with sufficient cognitive ability to complete functional assessments\n* Presence of healthy control participants without MIH for comparison\n* Mixed dentition period\n* Signed informed consent obtained from parents or legal guardians\n\nExclusion Criteria:\n\n* Temporomandibular disorders or orofacial pain\n* Systemic diseases or regular medication use affecting mastication\n* History of orthodontic treatment or parafunctional habits\n* Craniofacial anomalies or developmental dental anomalies\n* Extensive prosthetic restorations affecting chewing function\n* Uncooperative children unable to complete examination procedures\n* Acute dental infection or pain requiring emergency treatment",true,"ALL","7 Years","13 Years",{"count":45,"type":46},68,"ESTIMATED","INTERVENTIONAL",[49],"NA","This study aims to evaluate right-left chewing balance and masticatory function in children with Molar-Incisor Hypomineralization (MIH) before and after restorative treatment. MIH is a developmental enamel defect that may cause tooth sensitivity, discomfort during chewing, and functional asymmetry.\n\nChildren aged 7 to 12 years with bilateral MIH affecting the first permanent molars will receive glass hybrid restorative treatment. Right-left occlusal force distribution will be assessed using a digital occlusal analysis system. In addition, chewing side preference and chewing balance will be evaluated using a standardized chewing gum protocol. These two assessment methods will be used together to provide complementary information about masticatory function.\n\nMeasurements will be performed before treatment and during follow-up visits after treatment. The findings obtained from children with MIH will also be compared with healthy children without MIH. The study aims to determine whether restorative treatment improves chewing balance and functional oral performance in children with MIH.",[52,53,54,55],"Molar-Incisor Hypomineralization (MIH)","Masticatory Performance","Occlusal Analysis","Chewing Function","NOT_YET_RECRUITING","2026-06-02",{"date":59,"type":60},"2026-06-04","ACTUAL",{"date":62,"type":46},"2026-05-11",{"date":64,"type":46},"2026-12-20",{"name":5,"class":6}]