[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100552053":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":40,"centralContacts":44,"locations":31,"responsibleParty":53,"collaborators":31,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":31,"eligibilityCriteria":63,"healthyVolunteers":64,"sex":65,"minAge":66,"maxAge":67,"enrollmentInfo":68,"targetDuration":31,"studyType":71,"phases":72,"briefSummary":74,"conditions":75,"keywords":31,"overallStatus":77,"whyStopped":31,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":31},{"fullName":5,"class":6},"Ain Shams University","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Group A: The premixed Bioceramic NeoPUTTY® group","EXPERIMENTAL","Cases will be evaluated clinically and radiographically to obtain baseline data. Local anesthesia will be administered and then rubber dam isolation will be performed. Pulpotomy procedure will be performed after hemostasis followed by covering pulp stump with Premixed Bioceramic NeoPUTTY® then final composite restoration will be applied.",[13],"Procedure: premixed Bioceramic NeoPUTTY®",{"label":15,"type":10,"description":16,"interventionNames":17},"Group B: The Biodentine™ group","Cases will be evaluated clinically and radiographically to obtain baseline data. Local anesthesia will be administered and then rubber dam isolation will be performed. Pulpotomy procedure will be performed after hemostasis followed by covering pulp stump with Biodentine™ then final composite restoration will be applied.",[18],"Procedure: Biodentine™",{"label":20,"type":21,"description":22,"interventionNames":23},"Group C: the root canal treatment group","ACTIVE_COMPARATOR","Root canal treatment will be performed to the control group followed by composite restoration.",[24],"Procedure: Root canal treatment",[26,32,36],{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"PROCEDURE","premixed Bioceramic NeoPUTTY®","Pulpotomy procedure will be performed after hemostasis followed by covering pulp stump with Premixed Bioceramic then final composite restoration will be applied. clinical evaluation will be done at baseline, 3, 6, 9 and 12 months.",[9],null,{"type":27,"name":33,"description":34,"armGroupLabels":35,"otherNames":31},"Biodentine™","Pulpotomy procedure will be performed after hemostasis followed by covering pulp stump with Premixed Bioceramic or Biodentine™ according to the corresponding group then final composite restoration will be applied. clinical evaluation will be done at baseline, 3, 6, 9 and 12 months.",[15],{"type":27,"name":37,"description":38,"armGroupLabels":39,"otherNames":31},"Root canal treatment","Root canal treatment will be performed to the control group followed by composite restoration. clinical evaluation will be done at baseline, 3, 6, 9 and 12 months.",[20],[41],{"name":42,"affiliation":5,"role":43},"Nagwa Khattab, BDS,MSc, MD","STUDY_DIRECTOR",[45,50],{"name":46,"role":47,"phone":48,"phoneExt":31,"email":49},"Sally Emad, BDS,MSc","CONTACT","01227788137","sallyghobrial@dent.asu.edu.eg",{"name":51,"role":47,"phone":31,"phoneExt":31,"email":52},"Dina Darwish, BDS,MSc, MD","dinadarwish@dent.asu.edu.eg",{"type":54,"investigatorFullName":55,"investigatorTitle":56,"investigatorAffiliation":5,"oldNameTitle":31,"oldOrganization":31},"PRINCIPAL_INVESTIGATOR","Sally Emad Nathan Ghobrial","Assistant Lecturer","100552053","evaluation-of-pulpotomy-using-two-different-agents-in-mature-anterior-teeth-with-pulpitis-100552053",false,"NCT06468085","Evaluation of Pulpotomy Using Two Different Agents in Mature Anterior Teeth With Pulpitis","Clinical and Radiographic Evaluation of Premixed Bioceramic Putty and Biodentine™ Pulpotomy in Mature Permanent Anterior Teeth With Signs of Pulpitis: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Children and adolescents of both sexes aged between 9 and 14 years old.\n* Vital mature permanent anterior teeth with deep caries lesions that approach the pulp with signs of pulpitis and respond positive to cold pulp testing.\n* Vital mature permanent anterior teeth with pulpal exposure that occurred during caries excavation.\n* Patients presented immediately after suffering recent trauma (at the same day) to mature anterior teeth that had resulted in a crown fracture with pulp exposure.\n\nExclusion Criteria:\n\n* Teeth with signs of infection such as swelling, sinus tract or pathological mobility or excessive mobility.\n* Teeth with excessive bleeding from amputated radicular stumps\n* Teeth showing radiographic evidence of pathologic root resorption, periapical pathology and calcifications in the canals.\n* Lack of patient\u002Fparent compliance and cooperation.\n* Children who are physically or mentally disabled or having any medical condition that will complicate the treatment.\n* Patients allergic to any medicaments used.",true,"ALL","9 Years","14 Years",{"count":69,"type":70},48,"ESTIMATED","INTERVENTIONAL",[73],"NA","the study will evaluate the clinical and radiological success of mature permanent anterior teeth pulpotomy in children and adolescents with signs of pulpitis using two different Biomimetic materials (NeoPutty® and Biodentine™) as a pulp dressing material in comparison to root canal treatment at 3, 6, 9 and 12 months follow up.",[76],"Pulpitis","NOT_YET_RECRUITING","2024-06-20",{"date":80,"type":81},"2024-06-21","ACTUAL",{"date":83,"type":70},"2024-07-01",{"date":85,"type":70},"2026-07-01",{"name":5,"class":6}]