[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100389798":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":34,"locations":39,"responsibleParty":64,"collaborators":26,"id":66,"slug":67,"hasResults":68,"nctId":69,"briefTitle":70,"officialTitle":70,"acronym":26,"eligibilityCriteria":71,"healthyVolunteers":68,"sex":72,"minAge":73,"maxAge":74,"enrollmentInfo":75,"targetDuration":26,"studyType":78,"phases":79,"briefSummary":81,"conditions":82,"keywords":85,"overallStatus":42,"whyStopped":26,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"Yale University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Vitamin D Supplement","EXPERIMENTAL","Patients will take vitamin D tablet with 4,000IU daily for 6 months.",[13],"Drug: Vitamin D 4000IU daily",{"label":15,"type":16,"description":17,"interventionNames":18},"Placebo","PLACEBO_COMPARATOR","Patients will take placebo for 6 months",[19],"Drug: Placebo",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","Vitamin D 4000IU daily","Randomized to receive vitamin D 4000IU daily",[9],null,{"type":22,"name":15,"description":28,"armGroupLabels":29,"otherNames":26},"Randomized to placebo daily",[15],[31],{"name":32,"affiliation":5,"role":33},"Alla Vash-Margita, MD","PRINCIPAL_INVESTIGATOR",[35],{"name":32,"role":36,"phone":37,"phoneExt":26,"email":38},"CONTACT","203-785-4010","alla.vash-margita@yale.edu",[40],{"facility":41,"status":42,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"Yale New Haven Children's Hospital","RECRUITING","New Haven","Connecticut","06510","United States","US",{"type":49,"coordinates":50},"Point",[51,52],-72.92816,41.30815,{"lat":52,"lon":51},[55,58,62],{"name":56,"role":36,"phone":57,"phoneExt":26,"email":38},"Alla Vash-Margita, Principal Investigator, MD","203-785-7409",{"name":59,"role":36,"phone":60,"phoneExt":26,"email":61},"Kathleen Miclette, nurse coordinator, RN","203-444-3720","kathleen.miclette@ynhh.org",{"name":63,"role":33,"phone":26,"phoneExt":26,"email":26},"Alla Vash-Margita, Associate Professor, MD",{"type":65,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100389798","evaluation-of-the-clinical-and-psychological-impact-of-vitamin-d-replacement-in-adolescent-females-at-risk-for-polycystic-ovarian-syndrome-pcos-100389798",false,"NCT04355572","Evaluation of the Clinical and Psychological Impact of Vitamin D Replacement in Adolescent Females at Risk for Polycystic Ovarian Syndrome (PCOS)","Inclusion Criteria:\n\n\\- Postmenarchal adolescent females aged 13-21 who meet modified Rotterdam criteria for PCOS, with a serum vitamin D level between 6-29 ng\u002FmL.\n\nExclusion Criteria:\n\n* Other causes for hyperandrogenism,\n* Chronic renal diseases,\n* Acquired or inherited calcium and vitamin D metabolic disorders.","FEMALE","13 Years","21 Years",{"count":76,"type":77},60,"ESTIMATED","INTERVENTIONAL",[80],"NA","This study is a double blind, placebo controlled, randomized trial of study subjects with PCOS and low vitamin D to 2 groups- placebo and vitamin D replacement. Participants and investigators will be blinded to treatment modality until the end of the trial period",[83,84],"Polycystic Ovarian Syndrome in Adolescent Females","Vitamin D Deficiency",[86],"Anti-Mullerian Hormone (AMH)","2026-02-19",{"date":89,"type":90},"2026-02-23","ACTUAL",{"date":92,"type":77},"2026-05",{"date":94,"type":77},"2027-12-01",{"name":5,"class":6},1]