[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100581727":3},{"organization":4,"armGroups":7,"interventions":28,"overallOfficials":34,"centralContacts":43,"locations":34,"responsibleParty":53,"collaborators":57,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":34,"eligibilityCriteria":66,"healthyVolunteers":67,"sex":68,"minAge":69,"maxAge":70,"enrollmentInfo":71,"targetDuration":34,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":80,"overallStatus":85,"whyStopped":34,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":34},{"fullName":5,"class":6},"Ege University","OTHER",[8,16,20,24],{"label":9,"type":10,"description":11,"interventionNames":12},"G1 Colgate","ACTIVE_COMPARATOR","Participants with dentin sensitivity in at least three teeth will be divided into four main groups. Subsequently, each of these main groups will be further divided into three subgroups.\n\n1-) Colgate Sensitivity Pro-Solution (Pro-argin, USA) Subgroup 1a: Laser Subgroup 1b: 3M Clinpro White Varnish (TCP, USA) Subgroup 1c: Control (distilled water)",[13,14,15],"Device: laser treatment","Device: application of desensitizing agent","Other: Placebo",{"label":17,"type":10,"description":18,"interventionNames":19},"G2 Zubio","2-) Zubio (Nanohydroxyapatite, Turkey) Subgroup 2a: Laser Subgroup 2b: 3M Clinpro White Varnish (TCP, USA) Subgroup 2c: Control (distilled water)",[13,14,15],{"label":21,"type":10,"description":22,"interventionNames":23},"G3 Sensodyn","3-) Sensodyne Repair and Protect (NovaMin, USA) Subgroup 3a: Laser Subgroup 3b: 3M Clinpro White Varnish (TCP, USA) Subgroup 3c: Control (distilled water)",[13,14,15],{"label":25,"type":10,"description":26,"interventionNames":27},"G4 GC","4-) GC Tooth Mousse (CPP-ACP, Australia) Subgroup 4a: Laser Subgroup 4b: 3M Clinpro White Varnish (TCP, USA) Subgroup 4c: Control (distilled water)",[13,14,15],[29,35,39],{"type":30,"name":31,"description":32,"armGroupLabels":33,"otherNames":34},"DEVICE","laser treatment","In the laser treatment groups, the Fotona LightWalker® Erbium laser (2,940 nm) will be used, with each session lasting five minutes. During treatment, the energy density will be set to 20 J\u002Fcm², and the laser tip will be held perpendicular to the target area, applied in continuous and contact modes.",[9,17,21,25],null,{"type":30,"name":36,"description":37,"armGroupLabels":38,"otherNames":34},"application of desensitizing agent","Mix the product for 15 s. Apply in a thin layer on treatment area(s) with aid of a \"microbrush\", with no rinsing or removal",[9,17,21,25],{"type":6,"name":40,"description":41,"armGroupLabels":42,"otherNames":34},"Placebo","Simulation of a single layer application (15s) , with the aid of a \"microbrush\", on the surface of the tooth and with no rinsing or removal.",[9,17,21,25],[44,49],{"name":45,"role":46,"phone":47,"phoneExt":34,"email":48},"Cem Peşkersoy","CONTACT","+905326362659","dtcempeskersoy@hotmail.com",{"name":50,"role":46,"phone":51,"phoneExt":34,"email":52},"hilal bücekler","+905399884295","hilalbucekler@gmail.com",{"type":54,"investigatorFullName":55,"investigatorTitle":56,"investigatorAffiliation":5,"oldNameTitle":34,"oldOrganization":34},"PRINCIPAL_INVESTIGATOR","Cem Peskersoy","Doç. Dr.",[58],{"name":59,"class":6},"The Scientific and Technological Research Council of Turkey","100581727","evaluation-of-the-combined-effect-of-bioactive-toothpastes-desensitizing-agents-and-er-yag-laser-on-dentin-hypersensitivity-an-in-vivo-study-100581727",false,"NCT06854068","Evaluation of the Combined Effect of Bioactive Toothpastes, Desensitizing Agents and Er-YAG Laser on Dentin Hypersensitivity: an In-Vivo Study","In-Vivo Evaluation of the Effect of Bioactive Material-Containing Toothpastes and Combined Use of Er-YAG Laser on Dentin Hypersensitivity","Inclusion Criteria:\n\n1. Individuals over the age of 18,\n2. Individuals with good oral hygiene,\n3. Individuals without systemic contraindications for treatment,\n4. Individuals who are reliable for periodic follow-ups, cooperative, and willing to participate in the study,\n5. Individuals with sensitivity in at least three teeth,\n6. Individuals who have been using a standard toothpaste containing 1100 ppm fluoride for at least one month.\n\nExclusion Criteria:\n\n1. Individuals with a history of alcohol, drug, or medication addiction,\n2. Individuals known to be unable to attend follow-up sessions,\n3. Individuals with allergies to any of the products used in the study,\n4. Individuals with unstable mental or physical conditions,\n5. Pregnant or breastfeeding individuals, as well as those planning pregnancy during the study.",true,"ALL","18 Years","84 Years",{"count":72,"type":73},40,"ESTIMATED","INTERVENTIONAL",[76],"NA","Here's the revised version with the corrected treatment and follow-up session schedule:\n\n\\---\n\nThe aim of this clinical trial is to evaluate the effectiveness of bioactive toothpastes, desensitizing agents, and Er-YAG laser treatments in reducing dentin hypersensitivity. This study also aims to assess the safety and comparative efficiency of these treatment methods. The main research questions are:\n\n* Do bioactive toothpastes, desensitizing agents, and laser treatments individually or in combination reduce dentin hypersensitivity?\n* Are there any adverse effects associated with these treatments?\n\nParticipants will:\n\n* Be randomly assigned to one of four treatment groups, each using a specific toothpaste (Pro-Argin, Nano-Hydroxyapatite, NovaMin, or CPP-ACP), alongside desensitizing agents, laser treatments, or a placebo.\n* Receive two treatment sessions: the first at baseline and the second one week later.\n* Attend follow-up evaluations at the 2nd week, 1st month, and 3rd month to assess dentin hypersensitivity using the Visual Analog Scale (VAS) and dental unit air-water sprays.\n\nResearchers will compare the outcomes across groups using statistical analyses (Kolmogorov-Smirnov, Kruskal-Wallis, and Pearson\u002FSpearman tests) to determine the most effective approach for managing dentin hypersensitivity.",[79],"Dentin Hypersensitivity",[81,82,83,84],"dentin hypersensitivity","laser","desensitization agent","toothpaste","NOT_YET_RECRUITING","2025-02-25",{"date":88,"type":89},"2025-03-03","ACTUAL",{"date":91,"type":73},"2025-05-01",{"date":93,"type":73},"2026-09-01",{"name":5,"class":6}]