[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100635305":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":37,"responsibleParty":47,"collaborators":26,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":55,"acronym":26,"eligibilityCriteria":56,"healthyVolunteers":53,"sex":57,"minAge":58,"maxAge":59,"enrollmentInfo":60,"targetDuration":26,"studyType":63,"phases":64,"briefSummary":66,"conditions":67,"keywords":69,"overallStatus":73,"whyStopped":26,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":83},{"fullName":5,"class":6},"Biruni University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Hybrid Cardiac Rehabilitation Group","EXPERIMENTAL","Participants will receive a hybrid cardiac rehabilitation program consisting of center-based supervised exercise sessions combined with home-based telerehabilitation-supported walking and strengthening exercises.",[13],"Behavioral: Hybrid Cardiac Rehabilitation",{"label":15,"type":16,"description":17,"interventionNames":18},"Supervised Exercise Therapy Group","ACTIVE_COMPARATOR","Participants will receive conventional center-based supervised exercise therapy including treadmill walking and strengthening exercises under the supervision of a physiotherapist.",[19],"Behavioral: Supervised Exercise Therapy",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"BEHAVIORAL","Hybrid Cardiac Rehabilitation","The hybrid cardiac rehabilitation intervention consists of a structured exercise program combining center-based supervised treadmill walking sessions with home-based walking and strengthening exercises supported by telerehabilitation. Exercise intensity and progression are individualized based on perceived exertion and symptom tolerance. Participants are remotely monitored using wearable activity tracking devices and regular physiotherapist follow-up.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Supervised Exercise Therapy","Supervised exercise therapy consists of a center-based exercise program performed under the supervision of a physiotherapist. The program includes treadmill walking and strengthening exercises delivered according to established peripheral artery disease rehabilitation guidelines. Exercise intensity and progression are individualized based on perceived exertion, symptom tolerance, and functional capacity.",[15],[32],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Duygu Yalçınkaya, MSc","CONTACT","+90 539 594 44 51","dyalcinkaya@biruni.edu.tr",[38],{"facility":5,"status":26,"city":39,"state":26,"zip":26,"country":40,"countryCode":26,"cosmosGeoPoint":41,"geoPoint":46,"contacts":26},"Istanbul","Turkey (Türkiye)",{"type":42,"coordinates":43},"Point",[44,45],28.94966,41.01384,{"lat":45,"lon":44},{"type":48,"investigatorFullName":49,"investigatorTitle":50,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Buket AKINCI","Prof. Dr.","100635305","evaluation-of-the-effectiveness-of-hybrid-cardiac-rehabilitation-in-peripheral-artery-disease-100635305",false,"NCT07550959","Evaluation of the Effectiveness of Hybrid Cardiac Rehabilitation in Peripheral Artery Disease","Inclusion Criteria:\n\n* Diagnosis of peripheral artery disease with stable intermittent claudication.\n* Fontaine stage I-II or Rutherford category 1-3.\n* Age between 50 and 70 years.\n* Ability to walk independently without assistive devices.\n* Medically stable and eligible for exercise-based rehabilitation.\n* Willingness to participate in the study and to comply with the exercise program.\n* Provision of written informed consent prior to participation.\n\nExclusion Criteria:\n\n* Critical limb ischemia or rest pain.\n* Recent lower extremity revascularization or major surgery within the past 6 months.\n* Unstable cardiovascular conditions (e.g., unstable angina, uncontrolled arrhythmias).\n* Severe pulmonary, neurological, or musculoskeletal disorders limiting exercise participation.\n* Severe cognitive impairment or psychiatric conditions affecting compliance.\n* Participation in another structured exercise or rehabilitation program within the past 3 months.\n* Any medical condition deemed by the investigator to interfere with safe participation in the study.","ALL","50 Years","70 Years",{"count":61,"type":62},40,"ESTIMATED","INTERVENTIONAL",[65],"NA","Peripheral artery disease (PAD) is a common atherosclerotic condition characterized by reduced blood flow to the lower extremities, leading to intermittent claudication, decreased walking capacity, and impaired quality of life. Supervised exercise therapy is recommended as the first-line non-invasive treatment for patients with PAD; however, participation in center-based programs is often limited due to accessibility, time constraints, and symptom-related barriers.\n\nThis randomized controlled study aims to evaluate the clinical effectiveness of a hybrid cardiac rehabilitation program compared with conventional supervised exercise therapy in individuals diagnosed with peripheral artery disease. Participants will be randomly assigned to either a hybrid cardiac rehabilitation group or a supervised exercise therapy group.\n\nThe hybrid cardiac rehabilitation program will combine center-based supervised exercise sessions with home-based telerehabilitation, supported by remote monitoring and wearable activity tracking devices. The supervised exercise therapy group will receive a fully center-based, physiotherapist-supervised exercise program. Both interventions will be delivered over a 12-week period.\n\nPrimary outcomes will include walking performance and functional capacity. Secondary outcomes will assess exercise adherence, symptom severity, physical activity levels, and quality of life. The results of this study are expected to provide evidence on the feasibility and effectiveness of hybrid cardiac rehabilitation as an alternative rehabilitation model for patients with peripheral artery disease.",[68],"Peripheral Arterial Disease",[70,23,28,71,72],"peripheral arterial disease","Telerehabilitation","Intermittent Claudication","NOT_YET_RECRUITING","2026-04-22",{"date":76,"type":77},"2026-04-24","ACTUAL",{"date":79,"type":62},"2026-09-16",{"date":81,"type":62},"2027-04-16",{"name":5,"class":6},1]