[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100541946":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":11,"centralContacts":20,"locations":27,"responsibleParty":40,"collaborators":11,"id":42,"slug":43,"hasResults":44,"nctId":45,"briefTitle":46,"officialTitle":46,"acronym":47,"eligibilityCriteria":48,"healthyVolunteers":44,"sex":49,"minAge":50,"maxAge":11,"enrollmentInfo":51,"targetDuration":11,"studyType":54,"phases":55,"briefSummary":57,"conditions":58,"keywords":11,"overallStatus":60,"whyStopped":11,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":70},{"fullName":5,"class":6},"GCS Ramsay Santé pour l'Enseignement et la Recherche","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Skin biopsy","EXPERIMENTAL",null,[13],"Procedure: skin biopsy",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":11},"PROCEDURE","skin biopsy","Samples will be taken under local anaesthetic (after injection of 1 cc of Xylocaine without adrenaline) using a 4 mm diameter dermal biopsy punch. The biopsy will be performed on the buttocks. Fragments are stored in 15-mL polypropylene tubes in PBS at 4°C.",[9],[21],{"name":22,"role":23,"phone":24,"phoneExt":25,"email":26},"Geoffroy NOURISSAT, MD","CONTACT","07 69 99 67 30","33","gnourissat@wanadoo.fr",[28],{"facility":29,"status":11,"city":30,"state":11,"zip":31,"country":32,"countryCode":33,"cosmosGeoPoint":34,"geoPoint":39,"contacts":11},"Clinique Maussins-Nollet","Paris","75019","France","FR",{"type":35,"coordinates":36},"Point",[37,38],2.3488,48.85341,{"lat":38,"lon":37},{"type":41,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100541946","evaluation-of-the-effects-of-cross-linking-on-the-biomechanical-characteristics-of-skin-samples-from-patients-with-classic-or-hypermobile-ehlers-danlos-syndrome-100541946",false,"NCT06336473","Evaluation of the Effects of Cross Linking on the Biomechanical Characteristics of Skin Samples From Patients With Classic or Hypermobile Ehlers-Danlos Syndrome","SEDSKIN","Inclusion Criteria:\n\n* Patient aged 18 or over, having read and signed the consent form for participation in the study\n* Patient with classic or hypermobile Ehlers-Danlos syndrome\n* Regularly followed-up at the non-vascular Ehlers-Danlos Syndrome Reference Center at Garches Hospital.\n\nExclusion Criteria:\n\n* Patient under court protection, guardianship or curatorship\n* Pregnant or breast-feeding patient\n* Patient not affiliated to the French social security system\n* Impossibility of giving the subject informed information and\u002For written informed consent: dementia, psychosis, disturbed consciousness, non-French-speaking patient\n* Contraindication to anaesthesia or allergy to local anaesthetic product","ALL","18 Years",{"count":52,"type":53},28,"ESTIMATED","INTERVENTIONAL",[56],"NA","The main aim of this study is to evaluate the effect of cross linking on the elasticity of skin samples from patients with non-vascular Ehlers-Danlos Syndrome (hEDS or cEDS).",[59],"Ehlers-Danlos Syndrome","NOT_YET_RECRUITING","2024-06-21",{"date":63,"type":64},"2024-06-24","ACTUAL",{"date":66,"type":53},"2024-09-03",{"date":68,"type":53},"2025-07-31",{"name":5,"class":6},1]