[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100633249":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":18,"centralContacts":25,"locations":31,"responsibleParty":45,"collaborators":18,"id":49,"slug":50,"hasResults":51,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":18,"eligibilityCriteria":55,"healthyVolunteers":51,"sex":56,"minAge":57,"maxAge":18,"enrollmentInfo":58,"targetDuration":18,"studyType":61,"phases":62,"briefSummary":64,"conditions":65,"keywords":67,"overallStatus":34,"whyStopped":18,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":80},{"fullName":5,"class":6},"Firat University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Experimental Group","EXPERIMENTAL","Patients with Multiple Sclerosis who will receive laughter yoga in addition to routine care.",[13],"Behavioral: Laughter Yoga",{"label":15,"type":16,"description":17,"interventionNames":18},"Control Group","NO_INTERVENTION","Patients with Multiple Sclerosis who will receive routine care without laughter yoga.",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"BEHAVIORAL","Laughter Yoga","A complementary intervention including breathing exercises, stretching, relaxation techniques, and laughter exercises applied to patients with Multiple Sclerosis.",[9],[26],{"name":27,"role":28,"phone":29,"phoneExt":18,"email":30},"Gül DURAL, pHD","CONTACT","04242370000","gulkaya@firat.edu.tr",[32],{"facility":33,"status":34,"city":35,"state":18,"zip":18,"country":36,"countryCode":18,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"Gül DURAL","RECRUITING","Elâzığ","Turkey (Türkiye)",{"type":38,"coordinates":39},"Point",[40,41],39.22321,38.67431,{"lat":41,"lon":40},[44],{"name":27,"role":28,"phone":29,"phoneExt":18,"email":30},{"type":46,"investigatorFullName":47,"investigatorTitle":48,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"PRINCIPAL_INVESTIGATOR","Gul Dural","Assistant professor","100633249","evaluation-of-the-effects-of-laughter-yoga-100633249",false,"NCT07524231","Evaluation of the Effects of Laughter Yoga","Evaluation of the Effects of Laughter Yoga on Pain Intensity, Stress, and Beta-endorphin Levels in Patients With Multiple Sclerosis","Inclusion Criteria:\n\n* • Being over 18 years old\n\n  * Being able to communicate adequately\n  * Volunteering to participate in the research\n\nExclusion Criteria:\n\n* Unwillingness to participate in the study\n\nHaving severe cognitive impairment that prevents understanding or participation in the intervention\n\nHaving a psychiatric disorder that may affect participation in the study\n\nExperiencing an acute MS relapse during the study period\n\nHaving another serious neurological or chronic disease that may affect the study outcomes\n\nRegular participation in another complementary therapy program similar to laughter yoga\n\nCommunication problems that prevent participation in the intervention sessions","ALL","18 Years",{"count":59,"type":60},72,"ESTIMATED","INTERVENTIONAL",[63],"NA","This randomized controlled study aims to evaluate the effects of laughter yoga on pain intensity, fatigue, and beta-endorphin levels in patients with Multiple Sclerosis. Laughter yoga, a complementary therapy combining breathing exercises and laughter techniques, may help improve symptom management and psychological well-being in individuals with MS.",[66],"Multiple Sclerosis",[66,68,69,70],"pain","Laughter Yoga,","fatigue","2026-04-06",{"date":73,"type":74},"2026-04-13","ACTUAL",{"date":76,"type":74},"2026-03-10",{"date":78,"type":60},"2026-08-10",{"name":5,"class":6},1]