[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100627040":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":26,"responsibleParty":37,"collaborators":39,"id":44,"slug":45,"hasResults":46,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":26,"eligibilityCriteria":50,"healthyVolunteers":46,"sex":51,"minAge":52,"maxAge":53,"enrollmentInfo":54,"targetDuration":26,"studyType":57,"phases":58,"briefSummary":60,"conditions":61,"keywords":63,"overallStatus":67,"whyStopped":26,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":26},{"fullName":5,"class":6},"The Hong Kong Polytechnic University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"PEMF Therapy Intervention Patients with inflammatory KOA receive active PEMF therapy with optimized","EXPERIMENTAL","Active Pulsed Electromagnetic Field (PEMF) Therapy Active PEMF therapy at specific optimized parameters, administered twice a week for 8 weeks",[13],"Device: Pulsed Electromagnetic Field (PEMF) Therapy",{"label":15,"type":16,"description":17,"interventionNames":18},": Sham PEMF Treatment Patients with inflammatory KOA receive sham PEMF treatment (no effective elect","PLACEBO_COMPARATOR","Sham Pulsed Electromagnetic Field (PEMF) Treatments treatment (matching device without active electromagnetic field) administered twice a week for 8 weeks",[19],"Device: Sham Pulsed Electromagnetic Field (PEMF) Treatments",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Pulsed Electromagnetic Field (PEMF) Therapy","Assigned Interventions",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Sham Pulsed Electromagnetic Field (PEMF) Treatments","Matching device without active electromagnetic field) administered twice a week for 8 weeks",[15],[32],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Ye LI","CONTACT","+85227664842","ye-julie.li@polyu.edu.hk",{"type":38,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR",[40,42],{"name":41,"class":6},"Chinese University of Hong Kong",{"name":43,"class":6},"Zhujiang Hospital","100627040","evaluation-of-the-effects-of-pulsed-electromagnetic-field-on-inflammatory-knee-osteoarthritis-100627040",false,"NCT07443462","Evaluation of the Effects of Pulsed Electromagnetic Field on Inflammatory Knee Osteoarthritis","Double-blind, Randomized Controlled Pilot Study to Assess the Effect of Pulsed Electromagnetic Field on Inflammatory Knee Osteoarthritis","Inclusion Criteria:\n\n1. Knee visual analogue scale (VAS) pain of \\\u003C40 mm (0-100 mm)\n2. Effusion-synovitis or Hoffa synovitis MRI semi-quantitative score of ≥2 (used to determine inflammatory subtype KOA);\n3. Kellgren-Lawrence (KL) grade II and III\n4. Patients can listen, speak, read, and understand Chinese; understand the pilot study's requirements and are willing to cooperate with the investigator in conducting the pilot study\n5. Willing and able to provide written informed consent\n\nExclusion Criteria:\n\n1. Other inflammatory arthritis (e.g., gout, reactive arthritis, rheumatoid arthritis, psoriatic arthritis, and seronegative spondyloarthropathy) and systemic lupus erythematosus.\n2. Participants with usual KOA interventions\u002F treatments\n3. History of knee trauma\n4. Contraindications to MRI\n5. Administration of intra-articular, intramuscular, and oral glucocorticoids within the last 4\n6. Pregnancy and lactation","ALL","55 Years","80 Years",{"count":55,"type":56},50,"ESTIMATED","INTERVENTIONAL",[59],"NA","This study will assess the efficacy of pulsed electromagnetic field therapy in patients with inflammatory knee osteoarthritis confirmed by MRI-detected effusion-synovitis. Fifty participants will be randomly allocated into two groups. One group will receive active PEMF therapy at a specific optimized parameter twice a week for 8 weeks, while the other group will receive sham treatment using the same device without PEMF signal. The primary outcome is the change in WOMAC pain score, and secondary outcomes include knee function, stiffness, quality of life, and MRI-quantified structural changes.",[62],"Knee Osteoarthritis (Knee OA)",[64,65,66],"Pulsed electromagnetic field therapy","Knee osteoarthritis","Inflammatory subtype","NOT_YET_RECRUITING","2026-02-27",{"date":70,"type":71},"2026-03-02","ACTUAL",{"date":73,"type":56},"2026-02-15",{"date":75,"type":56},"2028-12-31",{"name":5,"class":6}]