[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100639065":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":56,"locations":63,"responsibleParty":166,"collaborators":170,"id":176,"slug":177,"hasResults":178,"nctId":179,"briefTitle":180,"officialTitle":181,"acronym":182,"eligibilityCriteria":183,"healthyVolunteers":178,"sex":184,"minAge":185,"maxAge":26,"enrollmentInfo":186,"targetDuration":26,"studyType":189,"phases":190,"briefSummary":192,"conditions":193,"keywords":200,"overallStatus":210,"whyStopped":26,"lastUpdateSubmitDate":211,"lastUpdatePostDateStruct":212,"startDateStruct":215,"completionDateStruct":217,"leadSponsor":219,"locationsCount":220},{"fullName":5,"class":6},"Istituto di Sistemi e Tecnologie Industriali Intelligenti per il Manifatturiero Avanzato","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Cycling with Virtual Park","EXPERIMENTAL","Participants perform cycling training using a commercially available ergometer (THERA-Trainer Tigo) combined with the VirtualPark virtual reality system. The intervention includes simultaneous motor and cognitive training (dual-task), with cognitive exercises targeting attention, inhibition, working memory, and navigation during cycling.",[13],"Device: Dual-task training with Virtual Reality",{"label":15,"type":16,"description":17,"interventionNames":18},"Cycling withouth Virtual Park","ACTIVE_COMPARATOR","Participants perform standard cycling training using the ergometer (THERA-Trainer Tigo) without virtual reality. This represents conventional motor rehabilitation (supportive care) without the addition of cognitive tasks delivered through VirtualPark.",[19],"Device: Cycling training",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Dual-task training with Virtual Reality","Participants perform cycling training using a commercially available ergometer combined with a non-immersive virtual reality system. Virtual Reality offers cognitive exercises targeting attention, inhibition, working memory, and navigation during cycling.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Cycling training","Participants perform standard cycling training without virtual reality-based tasks",[15],[32,35,38,41,44,47,50,53],{"name":33,"affiliation":5,"role":34},"Marta Mondellini, Psychologist","PRINCIPAL_INVESTIGATOR",{"name":36,"affiliation":37,"role":34},"Cira Fundarò, MD","Istituti Clinici Scientifici Maugeri IRCCS Montescano",{"name":39,"affiliation":40,"role":34},"Christian Lunetta, MD","Istituti Clinici Scientifici Maugeri IRCCS Milano Camaldoli",{"name":42,"affiliation":43,"role":34},"Stefania De Trane, MD","Istituti Clinici Scientifici Maugeri IRCCS Bari",{"name":45,"affiliation":46,"role":34},"Laura Marcuccio, MD","Istituti Clinici Scientifici Maugeri IRCCS Telese",{"name":48,"affiliation":49,"role":34},"Chiara Pavese, MD","Istituti Clinici Scientifici Maugeri IRCCS Pavia",{"name":51,"affiliation":52,"role":34},"Franco Molteni, MD","Centro di Riabilitazione Villa Beretta",{"name":54,"affiliation":55,"role":34},"Carmelo Chisari, MD","University of Pisa",[57,61],{"name":33,"role":58,"phone":59,"phoneExt":26,"email":60},"CONTACT","0039.0341.2350202","marta.mondellini@cnr.it",{"name":36,"role":58,"phone":26,"phoneExt":26,"email":62},"cira.fundaro@icsmaugeri.it",[64,81,96,110,125,139,152],{"facility":65,"status":26,"city":66,"state":66,"zip":67,"country":68,"countryCode":69,"cosmosGeoPoint":70,"geoPoint":75,"contacts":76},"Istituti a Carattere Scientifico Maugeri Bari","Bari","70124","Italy","IT",{"type":71,"coordinates":72},"Point",[73,74],16.86982,41.12066,{"lat":74,"lon":73},[77],{"name":78,"role":58,"phone":79,"phoneExt":26,"email":80},"Stefania De Trane","0039-080-7814111","stefania.detrane@icsmaugeri.it",{"facility":82,"status":26,"city":83,"state":84,"zip":85,"country":68,"countryCode":69,"cosmosGeoPoint":86,"geoPoint":90,"contacts":91},"Istituti a Carattere Scientifico Maugeri Telese","Telese Terme","Benevento","82037",{"type":71,"coordinates":87},[88,89],14.52681,41.21752,{"lat":89,"lon":88},[92],{"name":93,"role":58,"phone":94,"phoneExt":26,"email":95},"Laura Marcuccio","0039-0824909250","laura.marcuccio@icsmaugeri.it",{"facility":52,"status":26,"city":97,"state":98,"zip":99,"country":68,"countryCode":69,"cosmosGeoPoint":100,"geoPoint":104,"contacts":105},"Costa Masnaga","Lecco","23845",{"type":71,"coordinates":101},[102,103],9.27632,45.76963,{"lat":103,"lon":102},[106],{"name":107,"role":58,"phone":108,"phoneExt":26,"email":109},"Franco Molteni","0039- 031-8544215","franco56.molteni@gmail.com",{"facility":111,"status":26,"city":112,"state":113,"zip":114,"country":68,"countryCode":69,"cosmosGeoPoint":115,"geoPoint":119,"contacts":120},"Istituti a Carattere Scientifico Maugeri Milano Camaldoli","Milan","Milano","20138",{"type":71,"coordinates":116},[117,118],12.59836,42.78235,{"lat":118,"lon":117},[121],{"name":122,"role":58,"phone":123,"phoneExt":26,"email":124},"Christian Lunetta","0039-02-50725266","christian.lunetta@icsmaugeri.it",{"facility":126,"status":26,"city":127,"state":128,"zip":129,"country":68,"countryCode":69,"cosmosGeoPoint":130,"geoPoint":134,"contacts":135},"Istituti a Carattere Scientifico Maugeri Montescano","Montescano","Pavia","27040",{"type":71,"coordinates":131},[132,133],9.28366,45.03196,{"lat":133,"lon":132},[136],{"name":137,"role":58,"phone":138,"phoneExt":26,"email":62},"Cira Fundarò","0039-0385-247268",{"facility":140,"status":26,"city":128,"state":128,"zip":141,"country":68,"countryCode":69,"cosmosGeoPoint":142,"geoPoint":146,"contacts":147},"Istituti a Carattere Scientifico Maugeri Pavia","27100",{"type":71,"coordinates":143},[144,145],9.15917,45.19205,{"lat":145,"lon":144},[148],{"name":149,"role":58,"phone":150,"phoneExt":26,"email":151},"Chiara Pavese","0039-0382-592637","chiara.pavese@icsmaugeri.it",{"facility":153,"status":26,"city":154,"state":154,"zip":155,"country":68,"countryCode":69,"cosmosGeoPoint":156,"geoPoint":160,"contacts":161},"Università di Pisa","Pisa","56126",{"type":71,"coordinates":157},[158,159],10.4036,43.70853,{"lat":159,"lon":158},[162],{"name":163,"role":58,"phone":164,"phoneExt":26,"email":165},"Carmelo Chisari","0039-050-2210901","carmelo.chisari@unipi.it",{"type":167,"investigatorFullName":168,"investigatorTitle":169,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"SPONSOR_INVESTIGATOR","Marta Mondellini","Researcher",[171,173,175],{"name":172,"class":6},"Istituti Clinici Scientifici Maugeri SpA",{"name":174,"class":6},"Villa Beretta Rehabilitation Center",{"name":55,"class":6},"100639065","evaluation-of-the-impact-of-virtual-park-on-training-motivation-in-adult-patients-100639065",false,"NCT07616050","Evaluation of the Impact of Virtual Park on Training Motivation in Adult Patients","Evaluation of the Impact of a Rehabilitation Intervention Based on Cycling With Virtual Park on Training Motivation in Adult Patients","VP_Adults","Inclusion Criteria:\n\n* Informed consent to the study\n* subjects \\> 18 years and \\\u003C85 years\n* diagnosis of MCI according to the criteria of the Diagnostic and Statistical Manual of Mental Disorders VTh Edition (DSM V TR American Psychological Association 2013)\n* detection of ischemic stroke within 6 months preceding the study, frail elderly subjects (Gobbens RJ et al. 2010)\n* subjects affected by idiopathic Parkinson's disease according to the MDS-PD criteria (Postuma et al., 2015)\n* subjects affected by possible, probable and definite ALS according to the revised El Escorial criteria (Brooks Br, et al. 2000)\n* subjects affected by MS according to the McDonald criteria (2017) with disability measured with the EDSS (Expanded Disability Status Scale) \\\u003C= 8\n* patients with spinal cord injury of different etiology with incomplete spinal cord injury, AIS (ASIA impairment scale) grade C and D, MMSE \\>18\n* subjects naïve to the use of the RV\n* no therapeutic changes or rehabilitation interventions in the month prior to inclusion in the study\n* no ongoing behavioral disorders.\n\nExclusion Criteria:\n\n* Other concomitant neurological pathologies in addition to the one under study\n* presence of visual disturbances that do not allow access to the experimental virtual reality protocol\n* presence of impaired cardiorespiratory function or other organic instabilities that contraindicate ergometer training\n* severe osteoporosis","ALL","18 Years",{"count":187,"type":188},70,"ESTIMATED","INTERVENTIONAL",[191],"NA","The purpose of this clinical study is to evaluate the feasibility, usability, and motivational impact of VirtualPark, a virtual reality-based dual-task rehabilitation system, in adults with neurological and age-related conditions.\n\nVirtualPark is a virtual reality application designed to deliver cognitive exercises during cycling training using a commercially available ergometer (THERA-Trainer Tigo). The system integrates physical and cognitive tasks in simulated real-life environments.\n\nThe intervention integrates motor and cognitive training tasks targeting domains such as attention, inhibition, working memory, and navigation.\n\nThis is a prospective, multicenter, randomized, cross-over pilot study. It will compare cycling training performed with and without virtual reality. Participants will complete both intervention conditions over a 4-week period separated by a wash-out phase with standard rehabilitation activities. The order of conditions will be randomized.\n\nThe study will assess motivation during rehabilitation training, usability and user experience of the system, as well as exploratory effects on cognitive and motor performance, functional abilities, perceived exertion, and safety.\n\nThe study will enroll adult participants (≥18 years) with conditions such as stroke, Parkinson's disease, multiple sclerosis, amyotrophic lateral sclerosis, mild cognitive impairment, spinal cord injury, and frail older adults.",[194,195,196,197,198,199],"Post-stroke","Parkinson Disease","Amyotrophic Lateral Sclerosis","Mild Cognitive Impairment (MCI)","Multiple Sclerosis","Frailty at Older Adults",[201,202,196,203,198,204,205,206,207,208,209],"post-stroke","parkinson disease","Mild Cognitive Impairment","spinal cord injury","rehabilitation","dual-task","virtual reality","intrinsic motivation","frail elderly patients with multiple comorbidities","NOT_YET_RECRUITING","2026-05-25",{"date":213,"type":214},"2026-05-29","ACTUAL",{"date":216,"type":188},"2026-06",{"date":218,"type":188},"2027-01",{"name":168,"class":6},7]