[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100566050":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":21,"centralContacts":25,"locations":31,"responsibleParty":65,"collaborators":20,"id":67,"slug":68,"hasResults":69,"nctId":70,"briefTitle":71,"officialTitle":72,"acronym":73,"eligibilityCriteria":74,"healthyVolunteers":69,"sex":75,"minAge":76,"maxAge":20,"enrollmentInfo":77,"targetDuration":20,"studyType":80,"phases":81,"briefSummary":83,"conditions":84,"keywords":90,"overallStatus":53,"whyStopped":20,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":98,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":105,"locationsCount":106},{"fullName":5,"class":6},"University Hospital, Montpellier","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Adult emergency patients with acute respiratory distress","EXPERIMENTAL","Subjects aged ≥ 18 years presenting to the emergency department with ARD defined by respiratory rate (RR) \\> 25 and\u002For signs of struggle.\n\nEvery potentially eligible patient will have a right diaphragmatic ultrasound performed by a doctor trained in the technique.",[13],"Diagnostic Test: diaphragmatic ultrasound",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"DIAGNOSTIC_TEST","diaphragmatic ultrasound","The examination is performed with a phased array probe, also known as a cardiac probe. The technique used will be that described and validated in anterior studies: the patient is in the Fowler position: half-seated, at an angle of around 45 degrees. The patient is ventilating spontaneously, and no participation is required. The probe is positioned in the sub-costal region between the mid-clavicular and anterior axillary line on the right, and between the anterior and middle axillary line in the sub- or intercostal region on the left. The liver is used as an acoustic window for the right hemi-diaphragm. The probe is oriented medially, cranially and dorsally.\n\nThe operator switches to time-motion (TM) mode when an angle of over 70° is achieved between the upper part of the diaphragm and the analysis axis in the most cephalic part of the diaphragm. The image is frozen when 6 respiratory cycles have been measured.",[9],null,[22],{"name":23,"affiliation":5,"role":24},"DINO TIKVESA, MD","PRINCIPAL_INVESTIGATOR",[26],{"name":23,"role":27,"phone":28,"phoneExt":29,"email":30},"CONTACT","0467337974","+33","d-tikvesa@chu-montpellier.fr",[32,51],{"facility":33,"status":34,"city":35,"state":36,"zip":37,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"University Hospital of Nîmes","NOT_YET_RECRUITING","Nîmes","Gard","30900","France","FR",{"type":41,"coordinates":42},"Point",[43,44],4.35788,43.83665,{"lat":44,"lon":43},[47],{"name":48,"role":27,"phone":49,"phoneExt":29,"email":50},"Fabien COISY, MD","0612194369","fabien.coisy@gmail.com",{"facility":52,"status":53,"city":54,"state":55,"zip":56,"country":38,"countryCode":39,"cosmosGeoPoint":57,"geoPoint":61,"contacts":62},"University Hospital of Montpellier","RECRUITING","Montpellier","Hérault","34295",{"type":41,"coordinates":58},[59,60],3.87635,43.61093,{"lat":60,"lon":59},[63],{"name":64,"role":27,"phone":28,"phoneExt":29,"email":30},"Dino TIKVESA, MD",{"type":66,"investigatorFullName":20,"investigatorTitle":20,"investigatorAffiliation":20,"oldNameTitle":20,"oldOrganization":20},"SPONSOR","100566050","evaluation-of-the-relevance-of-diaphragmatic-stroke-ultrasound-for-the-etiological-diagnosis-of-acute-respiratory-distress-in-an-emergency-department-100566050",false,"NCT06650137","Evaluation of the Relevance of Diaphragmatic Stroke Ultrasound for the Etiological Diagnosis of Acute Respiratory Distress in an Emergency Department.","Evaluation of the Relevance of Diaphragmatic Stroke Ultrasound for the Etiological Diagnosis of Acute Respiratory Distress in an Emergency Department: a Prospective Multicenter Study.","EchoDiaph","Inclusion Criteria:\n\n* Patients 18 years of age or older;\n* Patient with ARD defined by respiratory rate (RR) strictly superior to 25 and\u002For signs of struggle which are: thoraco-abdominal rocking, active abdominal breathing, recruitment of extra-diaphragmatic respiratory muscles AND\n* peripheral saturation (SpO2) strictly inferior to 90% and\u002For hypercapnic acidosis (pH strictly inferior to 7.35 and pCO2 strictly superior to 45mmHg) on arterial blood gases;\n* Spontaneous ventilation.\n* Patients presenting a clinical severity score of Grade 1 with signs of struggle, as well as those with Grade 2 and Grade 3. A clinical severity score will be used as follows: Grade 1: Minimal polypnoea with respiratory rate (RR) between 20 and 25 ; Grade 2: Moderate polypnoea with respiratory rate (RR) between 25 and 35; Grade 3: Major polypnoea with respiratory rate (RR) between 35 to 50.\n\nExclusion Criteria:\n\n* Adult protected by law (guardianship, curatorship, legal protection)\n* Refusal of consent after information\n* Patient on non-invasive ventilation ;\n* Patient on mechanical ventilation;\n* Respiratory rate superior to 50\u002Fmin\n* Patient currently being treated for infectious pneumopathy with antibiotics;\n* Pregnant or breast-feeding women;\n* Patients with any known history of diaphragmatic pathologies.\n* Illiterate or unable to understand the purpose and methodology of the study.\n* Patient not affiliated to a social security scheme or not benefiting from such a scheme.\n* Person deprived of liberty (by judicial or administrative decision, or forced hospitalization)\n* Person participating in another study with an exclusion period still in progress,","ALL","18 Years",{"count":78,"type":79},100,"ESTIMATED","INTERVENTIONAL",[82],"NA","The goal of this Prospective interventional multicenter diagnostic study is to investigate the use of diaphragmatic ultrasound (DE) as a diagnostic tool in an adult emergency department for patients in acute respiratory distress.\n\nThe main question it aims to answer is to evaluate the relevance of measuring the Sum of Plateau Times (SPT) by Clinical Ultrasound in Emergency Medicine (CHEM) for the diagnosis of pneumopathy during acute respiratory distress (ARD) in the Emergency Department.\n\nSecondary objectives include the study of other diaphragmatic ultrasound parameters, inspiratory plateau time (IPT) and expiratory plateau time (EPT), and the diagnostic relevance of PTS for the diagnosis of decompensation of Chronic obstructive pulmonary disease (BPCO) and acute cardiogenic pulmonary edema (APO).\n\nEach eligible patient will have a right diaphragmatic ultrasound performed by a trained physician, then clinicobiological data will be collected later from medical records, and the etiological diagnosis will be established by a committee of 2 experts in the management of respiratory distress.",[85,86,87,88,89],"Pneumonia","Diaphragm; Movement","Diaphragmatic Ultrasound","Emergency Medical Services","Acute Respiratory Distress Syndrome (ARDS)",[91,92,85,93,94,95,96],"Diaphragmatic ultrasound,","ultrasonography","Diaphragm","Acute respiratory failure","Emergency","Diaphragmatic excursion","2024-12-03",{"date":99,"type":100},"2024-12-06","ACTUAL",{"date":102,"type":100},"2024-11-27",{"date":104,"type":79},"2026-11-01",{"name":5,"class":6},2]