[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100622142":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":25,"locations":32,"responsibleParty":54,"collaborators":10,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":62,"eligibilityCriteria":63,"healthyVolunteers":58,"sex":64,"minAge":65,"maxAge":10,"enrollmentInfo":66,"targetDuration":10,"studyType":69,"phases":10,"briefSummary":70,"conditions":71,"keywords":10,"overallStatus":35,"whyStopped":10,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":82},{"fullName":5,"class":6},"Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients with nasal obstruction",null,"Patients scheduled for surgery who underwent preoperative rhinomanometry",[13],"Procedure: preoperative rhinomanometry",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"PROCEDURE","preoperative rhinomanometry","The performance of AAR requires a pressure sensor placed within a facial mask to measure the pressure at the entrance of the ventilated nasal cavity. Another sensor is placed in the nasal vestibule of the contralateral nasal cavity to extrapolate the pressure at the exit of the ventilated nasal cavity. Measurements are therefore performed alternately on the right and left sides, but never on both sides simultaneously.\n\nAAR can be performed at rest in the seated position after 20 min in the supine position, or during forced inspiration.\n\nIn our practice, AAR is performed without the use of nasal decongestants.\n\nNormal values of nasal resistance measured by rhinomanometry are as follows:\n\n* Uninasal resistance ≤ 6 cmH₂O\u002FL\u002Fs (or 0.6 Pa\u002Fcm³\u002Fs);\n* Binasal resistance ≤ 3 cmH₂O\u002FL\u002Fs (or 0.3 Pa\u002Fcm³\u002Fs);\n* Uninasal resistance ≥ 0.6 Pa\u002Fcm³\u002Fs, with or without vasoconstrictor, suggests septal deviation;\n* Binasal resistance after VC ≥ 0.3 Pa\u002Fcm³\u002Fs suggests bilateral inferior turbinate hypertrophy",[9],[21],{"name":22,"affiliation":23,"role":24},"Heritsilavo Eloi RAMILISON, MD","Centre Hospitalier de la Dracénie - Draguignan","STUDY_DIRECTOR",[26],{"name":27,"role":28,"phone":29,"phoneExt":30,"email":31},"Sophie Lafond","CONTACT","0483772062","+33","sophie.lafond@ch-toulon.fr",[33],{"facility":34,"status":35,"city":36,"state":37,"zip":38,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"Centre Hospitalier de la Dracénie","RECRUITING","Draguignan","Var","83007","France","FR",{"type":42,"coordinates":43},"Point",[44,45],6.46458,43.53692,{"lat":45,"lon":44},[48,51],{"name":22,"role":28,"phone":49,"phoneExt":30,"email":50},"0494605869","heritsilavo.ramilison@ch-draguignan.fr",{"name":52,"role":28,"phone":49,"phoneExt":30,"email":53},"Charly BESSADIER, MD","charly.bessadier@ch-draguignan.fr",{"type":55,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100622142","evaluation-of-the-reliability-of-aar-as-an-independent-tool-for-surgical-indication-in-nasal-obstruction-100622142",false,"NCT07379775","Evaluation of the Reliability of AAR as an Independent Tool for Surgical Indication in Nasal Obstruction","Evaluation of the Reliability of Anterior Active Rhinomanometry as an Independent Tool for Surgical Indication in Nasal Obstruction","RHINOVE","Inclusion Criteria:\n\n1. Patients aged 18 years or older with nasal obstruction (NO).\n2. Patients scheduled for surgery: septoplasty ± turbinoplasty ± rhinoplasty for nasal obstruction.\n3. Patients who have undergone a preoperative rhinomanometry assessment.\n4. Patients consented to participation\n\nExclusion Criteria:\n\n1. Nasal polyps.\n2. Chronic edematous-purulent rhinosinusitis (e.g., cystic fibrosis).\n3. Crusting rhinosinusitis (e.g., sarcoidosis, granulomatosis with polyangiitis \\[Wegener's\\]).\n4. Current or previously treated nasal or sinus tumors, or patients undergoing tumor work-up","ALL","18 Years",{"count":67,"type":68},200,"ESTIMATED","OBSERVATIONAL","Nasal obstruction (NO) affects \\~30% of the population and is a very common reason for consultation in otorhinolaryngology (ORL). In the majority of cases, the origin is inflammatory (allergic rhinitis and chronic rhinosinusitis) while in a minority of cases, the origin is structural, including septal deviation and inferior turbinate hypertrophy.\n\nNO significantly impairs patients' quality of life (QoL) and olfactory performance and also represents a contributing factor and comorbidity in asthma and obstructive sleep apnea syndrome. Several questionnaires for assessing QoL are available and routinely used to evaluate the impact of NO on patients : VAS, NOSE score, SNOT-22, and RhinoQOL score.\n\nSeveral objective functional methods for assessing NO have been described : acoustic rhinometry, nasal peak inspiratory flow, and active rhinomanometry. Rhinomanometry is a simple, non-invasive functional assessment method that allows for objective and quantitative analysis of nasal airway patency, thereby complementing the clinical and imaging evaluation of NO.\n\nIt has been recommended for the diagnosis of NO in cases of chronic rhinitis and chronic rhinosinusitis with nasal polyposis. Rhinomanometry comprises anterior active (AAR), posterior, and per-nasal rhinomanometry. AAR is the most commonly used method and is the only technique routinely available to clinicians. AAR provides precise information regarding the presence of nasal resistance responsible for NO. However, it should not be used as a standalone diagnostic tool due to its poor correlation with QoL questionnaires such as VAS and NOSE.\n\nWhether used alone or in combination with nasal decongestants, AAR provides a high predictive value for the outcomes of septoplasty and laser-assisted turbinoplasty.\n\nWhen surgery is indicated, its performance depends on:\n\n* type of obstruction or anatomical abnormality identified on clinical examination and\u002For computed tomography and\u002For AAR;\n* patient's symptoms and impairment of QoL NOSE and SNOT-22;\n* failure of a well-conducted first-line medical nasal treatment. Thus, in cases of septal deviation, septoplasty is performed; in cases of inferior turbinate mucosal hypertrophy with failure of medical treatment, turbinoplasty is performed; and in cases of mixed lesions, septo-turbinoplasty is performed.\n\nHowever, the concordance rate between the surgical technique indicated by clinical examination and computed tomography and the indications suggested by AAR is only 48.5%.",[72],"Nasal Obstruction","2026-06-15",{"date":75,"type":76},"2026-06-16","ACTUAL",{"date":78,"type":76},"2026-01-27",{"date":80,"type":68},"2028-03",{"name":5,"class":6},1]