[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100576144":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":8,"centralContacts":12,"locations":17,"responsibleParty":33,"collaborators":7,"id":35,"slug":36,"hasResults":37,"nctId":38,"briefTitle":39,"officialTitle":40,"acronym":7,"eligibilityCriteria":41,"healthyVolunteers":37,"sex":42,"minAge":7,"maxAge":7,"enrollmentInfo":43,"targetDuration":7,"studyType":46,"phases":7,"briefSummary":47,"conditions":48,"keywords":50,"overallStatus":19,"whyStopped":7,"lastUpdateSubmitDate":54,"lastUpdatePostDateStruct":55,"startDateStruct":58,"completionDateStruct":60,"leadSponsor":62,"locationsCount":63},{"fullName":5,"class":6},"IRCCS Azienda Ospedaliero-Universitaria di Bologna","OTHER",null,[9],{"name":10,"affiliation":5,"role":11},"Francesca Vitali, MD","PRINCIPAL_INVESTIGATOR",[13],{"name":10,"role":14,"phone":15,"phoneExt":7,"email":16},"CONTACT","+390512144463","francesca.vitali@aosp.bo.it",[18],{"facility":5,"status":19,"city":20,"state":20,"zip":21,"country":22,"countryCode":23,"cosmosGeoPoint":24,"geoPoint":29,"contacts":30},"RECRUITING","Bologna","40138","Italy","IT",{"type":25,"coordinates":26},"Point",[27,28],11.33875,44.49381,{"lat":28,"lon":27},[31],{"name":10,"role":14,"phone":32,"phoneExt":7,"email":16},"051214463",{"type":34,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR","100576144","evaluation-of-urinary-biomarkers-trend-in-preterm-very-low-birth-weight-infants-100576144",false,"NCT06781476","Evaluation of Urinary Biomarkers Trend in Preterm Very Low Birth Weight Infants","Evaluation of Urinary Biomarkers Trend in Preterm Very Low Birth Weight Infants: Influence of Clinical and Therapeutic Factors","Inclusion Criteria:\n\n* Gestational age \\\u003C32 weeks or birth weight \\\u003C1500 g;\n* Admission at birth to the Neonatal Intensive Care Unit of the IRCCS A.O.U. of Bologna Policlinico di S. Orsola;\n* Obtaining informed consent from parents\u002Flegal representatives.\n\nExclusion Criteria:\n\n* malformations of the urinary system;\n* major congenital anomalies, including congenital heart disease;\n* syndromic picture or known genetic abnormalities;\n* perinatal asphyxia (defined by the finding on arterial blood gas from cord blood of pH≤7.0 or base excess ≤-12 mMol\u002FL and\u002For Apgar ≤5 or need for resuscitation at 10' of life);\n* infants who died in the first 48 hours of life or underwent major surgery during the study period.","ALL",{"count":44,"type":45},78,"ESTIMATED","OBSERVATIONAL","The purpose of this study is to define the temporal patterns of urinary biomarkers (CysC, EGF, KIM-1, NGAL, β2-Microglobulin, OPN, and MOD) in the first two weeks of life in preterm and\u002For very low birth weight (VLBW) infants in relation to the effect of specific factors (hsPDA, prenatal Doppler alterations) and drug therapies. Another objective is then to evaluate the predictivity of these biomarkers with respect to the occurrence of renal damage in preterm infants and possible cut-off values",[49],"Kidney Injury",[51,52,53],"kidney injury","urinary biomarkers","premature newborns","2025-01-13",{"date":56,"type":57},"2025-01-17","ACTUAL",{"date":59,"type":57},"2022-12-07",{"date":61,"type":45},"2025-06-15",{"name":5,"class":6},1]