[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100366637":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":24,"centralContacts":35,"locations":45,"responsibleParty":65,"collaborators":10,"id":67,"slug":68,"hasResults":69,"nctId":70,"briefTitle":71,"officialTitle":71,"acronym":72,"eligibilityCriteria":73,"healthyVolunteers":69,"sex":74,"minAge":75,"maxAge":10,"enrollmentInfo":76,"targetDuration":10,"studyType":79,"phases":10,"briefSummary":80,"conditions":81,"keywords":83,"overallStatus":48,"whyStopped":10,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":99},{"fullName":5,"class":6},"Centre Hospitalier Universitaire de Saint Etienne","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Renal mass patients",null,"Patients with renal mass requiring surgery (partial or total nephrectomy) will be included.\n\nThey will have an urinary sample.",[13],"Biological: Urinary sample",{"label":15,"type":10,"description":16,"interventionNames":17},"Control patients","Control patients (without renal mass) will be included. They will have an urinary sample.",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":10},"BIOLOGICAL","Urinary sample","Urinary sample (100 ml) will be collected in the urology department to analysis urinary exosomes.",[15,9],[25,28,32],{"name":26,"affiliation":5,"role":27},"Nicolas MOTTET, MD PhD","PRINCIPAL_INVESTIGATOR",{"name":29,"affiliation":30,"role":31},"Nora MALLOUK, PhD","UNIVERSITY SAINT-ETIENNE","STUDY_CHAIR",{"name":33,"affiliation":34,"role":31},"Guorong LI, PhD","CHU DE SAINT-ETIENNE",[36,41],{"name":26,"role":37,"phone":38,"phoneExt":39,"email":40},"CONTACT","(0)477828331","+33","nicolas.mottet@chu-st-etienne.fr",{"name":42,"role":37,"phone":43,"phoneExt":39,"email":44},"Arnauld GARCIN, CRA","(0)477120286","Arnauld.Garcin@chu-st-etienne.fr",[46],{"facility":47,"status":48,"city":49,"state":10,"zip":10,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"Chu Saint-Etienne","RECRUITING","Saint-Etienne","France","FR",{"type":53,"coordinates":54},"Point",[55,56],4.39,45.43389,{"lat":56,"lon":55},[59,60,63],{"name":26,"role":27,"phone":10,"phoneExt":10,"email":10},{"name":61,"role":62,"phone":10,"phoneExt":10,"email":10},"Hocine HABCHI, MD","SUB_INVESTIGATOR",{"name":64,"role":62,"phone":10,"phoneExt":10,"email":10},"Mohammed Amine MESSAOUD, MD",{"type":66,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100366637","evaluation-of-urinary-exosomes-presence-from-clear-cell-renal-cell-carcinoma-100366637",false,"NCT04053855","Evaluation of Urinary Exosomes Presence From Clear Cell Renal Cell Carcinoma","PEP-C","Inclusion Criteria:\n\nPatients:\n\n* All patients with renal mass requiring surgery (partial or total nephrectomy)\n* Social security affiliation\n* Signed informed consent\n\nControl :\n\n* Unscheduled nephrectomy\n* Social security affiliation\n* Signed informed consent\n\nExclusion Criteria:\n\n* Insufficient volume of urine sample (\\\u003C 100 ml)\n* Patients with a urinary catheter\n* Patients under court-ordered guardianship or curators","ALL","18 Years",{"count":77,"type":78},100,"ESTIMATED","OBSERVATIONAL","Clear cell renal cell carcinoma is diagnosed by imaging, sometimes associated with biopsy. This diagnosis is expensive, invasive and sometimes late. The development of a simple biological test for diagnosis is essential. Exosomes are 30 to 150 nm membrane vesicles secreted into the extracellular space by various living cells. These exosomes can be isolated from biological fluids, including urine. The recent study of urinary exosomes is a promising topic for analyzing tumor markers in urine. The investigator's goal is to develop a reliable technique for detecting tumor exosomes in urine in patients with clear cell renal cell carcinoma. The analysis of urinary exosomes could provide a new liquid biopsy tool for the early diagnosis of clear cell renal cell carcinoma.",[82],"Clear Cell Renal Cell Carcinoma",[84,85,86,87,88,89],"Clear cell renal cell carcinoma","Urinary exosomes","Detection","Electron microscopy technique","Flow cytometry","RT-qPCR","2026-05-05",{"date":92,"type":93},"2026-05-06","ACTUAL",{"date":95,"type":93},"2020-01-29",{"date":97,"type":78},"2026-08-01",{"name":5,"class":6},1]