[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100492483":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":18,"centralContacts":23,"locations":32,"responsibleParty":53,"collaborators":10,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":62,"eligibilityCriteria":63,"healthyVolunteers":58,"sex":64,"minAge":65,"maxAge":10,"enrollmentInfo":66,"targetDuration":10,"studyType":69,"phases":10,"briefSummary":70,"conditions":71,"keywords":73,"overallStatus":34,"whyStopped":10,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"University of Cologne","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients",null,"Patients with non-hypervolemic hypotonic hyponatremia",[13],"Other: Patients",[15],{"type":6,"name":9,"description":16,"armGroupLabels":17,"otherNames":10},"Patients will get study-specific measurements within first 5 days of standard of care treatment of hyponatremia or until discharge",[9],[19],{"name":20,"affiliation":21,"role":22},"Volker Burst, MD, Prof.","University Hospital of Cologne","PRINCIPAL_INVESTIGATOR",[24,29],{"name":25,"role":26,"phone":27,"phoneExt":10,"email":28},"Volker Burst, MD, Prof","CONTACT","+49 221-478-97222","volker.burst@uk-koeln.de",{"name":30,"role":26,"phone":10,"phoneExt":10,"email":31},"Sadrija Cukoski","sadrija.cukoski@uk-koeln.de",[33],{"facility":21,"status":34,"city":35,"state":10,"zip":36,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"RECRUITING","Cologne","50937","Germany","DE",{"type":40,"coordinates":41},"Point",[42,43],6.95,50.93333,{"lat":43,"lon":42},[46,49,50,51],{"name":47,"role":26,"phone":48,"phoneExt":10,"email":28},"Volker Burst, MD","+49(0)221 478 97222",{"name":30,"role":26,"phone":10,"phoneExt":10,"email":31},{"name":20,"role":22,"phone":10,"phoneExt":10,"email":10},{"name":30,"role":52,"phone":10,"phoneExt":10,"email":10},"SUB_INVESTIGATOR",{"type":22,"investigatorFullName":54,"investigatorTitle":55,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Volker Burst","Prof. Dr.","100492483","evaluation-of-volume-and-electrolyte-balance-in-hyponatremia-treatment---a-prospective-observational-trial-100492483",false,"NCT05692726","Evaluation of Volume and Electrolyte Balance in Hyponatremia Treatment - a Prospective Observational Trial","Evaluation of Volume and Electrolyte Balance in Hyponatremia Treatment - a Prospective Observational Trial (EvenT)","EvenT","Inclusion Criteria:\n\n* Adult patients ≥ 18 years\n* Hypotonic hyponatremia\n\n  * glucose-corrected plasma sodium \\\u003C130 mmol\u002Fl\n  * serum osmolality \\\u003C280 mosmol\u002Fkg or lack of signs of non-hypotonic hyponatremia\n\nExclusion Criteria:\n\n* Signs of extracellular volume expansion\n* Patients with liver cirrhosis and severe liver damage AST\u002FALT\\>3xULN, AP\\>6xULN, Bilirubin ≥ 3mg\u002Fdl\n* Patients with heart failure\n* Patients on dialysis and\u002For patients with oliguric renal impairment and plasma creatinine ≥ 3mg\u002Fdl\n* Patients after organ transplantation","ALL","18 Years",{"count":67,"type":68},50,"ESTIMATED","OBSERVATIONAL","To assess quantitatively the evolution over time of electrolyte-free water clearance and electrolyte mass balance in patients with non-hypervolemic hypotonic hyponatremia",[72],"Non-hypervolemic Hyponatremia",[74,75],"Electrolyte-free water clearance","hyponatremia","2025-09-10",{"date":78,"type":79},"2025-09-11","ACTUAL",{"date":81,"type":79},"2022-10-15",{"date":83,"type":68},"2026-09-30",{"name":5,"class":6},1]