[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100623343":3},{"organization":4,"armGroups":7,"interventions":30,"overallOfficials":36,"centralContacts":50,"locations":56,"responsibleParty":78,"collaborators":36,"id":81,"slug":82,"hasResults":83,"nctId":84,"briefTitle":85,"officialTitle":86,"acronym":36,"eligibilityCriteria":87,"healthyVolunteers":83,"sex":88,"minAge":89,"maxAge":90,"enrollmentInfo":91,"targetDuration":36,"studyType":94,"phases":95,"briefSummary":97,"conditions":98,"keywords":100,"overallStatus":59,"whyStopped":36,"lastUpdateSubmitDate":110,"lastUpdatePostDateStruct":111,"startDateStruct":114,"completionDateStruct":116,"leadSponsor":118,"locationsCount":119},{"fullName":5,"class":6},"October University for Modern Sciences and Arts","OTHER",[8,15,20,26],{"label":9,"type":10,"description":11,"interventionNames":12},"Arm A: Manual Instrumentation and Metapex","EXPERIMENTAL","Primary molar teeth will undergo pulpectomy using Manual instrumentation followed by obturation with iodoform-calcium hydroxide paste (Metapex).",[13,14],"Procedure: Manual Instrumentation","Drug: Iodoform-Calcium Hydroxide (Metapex)",{"label":16,"type":10,"description":17,"interventionNames":18},"Arm B: Rotary Instrumentation and Metapex","Primary molar teeth will undergo pulpectomy using rotary instrumentation followed by obturation with iodoform-calcium hydroxide paste (Metapex).",[14,19],"Procedure: Rotary Instrumentation",{"label":21,"type":22,"description":23,"interventionNames":24},"Arm C: Manual Instrumentation and ZOE","ACTIVE_COMPARATOR","Primary molar teeth will undergo pulpectomy using manual instrumentation followed by obturation with zinc oxide eugenol (ZOE).",[13,25],"Drug: Zinc Oxide Eugenol (ZOE)",{"label":27,"type":22,"description":28,"interventionNames":29},"Arm D: Rotary Instrumentation and ZOE","Primary molar teeth will undergo pulpectomy using rotary instrumentation followed by obturation with zinc oxide eugenol (ZOE).",[19,25],[31,37,42,46],{"type":32,"name":33,"description":34,"armGroupLabels":35,"otherNames":36},"PROCEDURE","Manual Instrumentation","Root canal preparation of primary molars will be performed using manual stainless-steel hand files with conventional step-back technique for cleaning and shaping of the root canals.",[9,21],null,{"type":38,"name":39,"description":40,"armGroupLabels":41,"otherNames":36},"DRUG","Iodoform-Calcium Hydroxide (Metapex)","Metapex (iodoform-calcium hydroxide paste) will be used as the obturating material for filling the prepared root canals of primary molars following pulpectomy.",[9,16],{"type":32,"name":43,"description":44,"armGroupLabels":45,"otherNames":36},"Rotary Instrumentation","Root canal preparation of primary molars will be performed using nickel-titanium rotary instruments according to the manufacturer's instructions to achieve effective cleaning and shaping of the root canals.",[16,27],{"type":38,"name":47,"description":48,"armGroupLabels":49,"otherNames":36},"Zinc Oxide Eugenol (ZOE)","Zinc oxide eugenol paste will be used as the obturating material for filling the prepared root canals of primary molars following pulpectomy.",[21,27],[51],{"name":52,"role":53,"phone":54,"phoneExt":36,"email":55},"Nanis Nasser, bachelor degree of dentistry","CONTACT","+201152791000","nanis.nasser1@msa.edu.eg",[57],{"facility":58,"status":59,"city":60,"state":61,"zip":62,"country":63,"countryCode":64,"cosmosGeoPoint":65,"geoPoint":70,"contacts":71},"Faculty of Dentistry, MSA University","RECRUITING","Giza","Giza Governorate","12611","Egypt","EG",{"type":66,"coordinates":67},"Point",[68,69],31.20861,30.00944,{"lat":69,"lon":68},[72,75],{"name":73,"role":53,"phone":74,"phoneExt":36,"email":55},"nanis Nasser, bachelor degree of dentistry","01152791000",{"name":76,"role":77,"phone":36,"phoneExt":36,"email":36},"nanis nasser, bachelor degree of dentistry","PRINCIPAL_INVESTIGATOR",{"type":77,"investigatorFullName":79,"investigatorTitle":80,"investigatorAffiliation":5,"oldNameTitle":36,"oldOrganization":36},"Nanis Nasser Anwar Moustafa","teacher assistant at pediatric dentistry department","100623343","evaluation-of-zinc-oxide-eugenol-and-iodoform-calcium-hydroxide-as-filling-materials-in-primary-molar-root-canals-prepared-by-rotary-and-manual-files-100623343",false,"NCT07395401","Evaluation of Zinc Oxide Eugenol and Iodoform-Calcium Hydroxide as Filling Materials in Primary Molar Root Canals Prepared by Rotary and Manual Files","Clinical and Radiographic Evaluation of Zinc Oxide Eugenol (ZOE) and Iodoform-Calcium Hydroxide (Metapex) as Filling Materials in Primary Molar Root Canals Prepared by Rotary and Manual Files: (Randomized Control Trial Study)","Inclusion Criteria:\n\n1. Apparently healthy cooperative children indicated for partial pulpectomy.\n2. Restorable primary molars.\n3. No mobility, or external pathological root resorption.\n\nExclusion Criteria:\n\n1. Uncooperative children.\n2. Children with systemic medical illness.\n3. More than 2\u002F3 of root resorbed.","ALL","5 Years","8 Years",{"count":92,"type":93},44,"ESTIMATED","INTERVENTIONAL",[96],"NA","This randomized controlled clinical trial aims to compare the clinical and radiographic outcomes of Zinc Oxide Eugenol (ZOE) and Iodoform-Calcium Hydroxide (Metapex) as root canal filling materials in primary molars prepared using either rotary or manual instrumentation techniques. Forty-four teeth from children aged 5-8 years indicated for pulpectomy will be randomly allocated into four equal groups based on the combination of instrumentation method and filling material. Clinical parameters-pain, mobility, and sensitivity-will be assessed using standardized scales, while radiographic outcomes, including root resorption and bone density, will be evaluated using Cone Beam Computed Tomography (CBCT) at baseline, 6 months, and 12 months. The study seeks to determine which obturation material and canal preparation technique yield superior healing, adaptation, and resorption compatible with the physiological process of primary tooth exfoliation. Findings are expected to inform evidence-based selection of endodontic materials and instrumentation methods in pediatric dentistry.",[99],"Carious Primary Molars Indicated for Pulpectomy",[101,102,103,104,105,106,107,108,109],"Iodoform-Calcium Hydroxide","Metapex","Zinc Oxide Eugenol","Manual Instrumentation Method","Rotary Instrumentation Method","pulpectomy","primary molars","radiographic assessment","clinical assessment","2026-02-01",{"date":112,"type":113},"2026-02-09","ACTUAL",{"date":115,"type":93},"2026-02-15",{"date":117,"type":93},"2026-03-15",{"name":5,"class":6},1]