[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100515257":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":21,"centralContacts":25,"locations":34,"responsibleParty":51,"collaborators":20,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":59,"eligibilityCriteria":60,"healthyVolunteers":55,"sex":61,"minAge":62,"maxAge":20,"enrollmentInfo":63,"targetDuration":20,"studyType":66,"phases":67,"briefSummary":69,"conditions":70,"keywords":72,"overallStatus":37,"whyStopped":20,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"Assistance Publique - Hôpitaux de Paris","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Definite prosthetic valve endocarditis","EXPERIMENTAL","adult patients with a valvular prosthesis presenting a definite infective endocarditis (IE) according to the ESC classification in force, not operated on in the acute phase (before the PET scan at the end of treatment) and presenting a pathological FDG uptake on the prosthetic valve at the start of curative antibiotic treatment.",[13],"Radiation: FDG-PET at the end of treatment for IE",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"RADIATION","FDG-PET at the end of treatment for IE","FDG-PET at the end of treatment for IE in patients with a prosthetic valve",[9],null,[22],{"name":23,"affiliation":5,"role":24},"François Rouzet, MD, PHD","PRINCIPAL_INVESTIGATOR",[26,31],{"name":23,"role":27,"phone":28,"phoneExt":29,"email":30},"CONTACT","01.40.25.64.11","33","francois.rouzet@aphp.fr",{"name":32,"role":27,"phone":20,"phoneExt":20,"email":33},"Xavier Duval, MD, PHD","xavier.duval@aphp.fr",[35],{"facility":36,"status":37,"city":38,"state":39,"zip":40,"country":39,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"Hôpital Bichat-Claude Bernard","RECRUITING","Paris","France","75018","FR",{"type":43,"coordinates":44},"Point",[45,46],2.3488,48.85341,{"lat":46,"lon":45},[49,50],{"name":23,"role":27,"phone":28,"phoneExt":29,"email":30},{"name":32,"role":27,"phone":20,"phoneExt":20,"email":33},{"type":52,"investigatorFullName":20,"investigatorTitle":20,"investigatorAffiliation":20,"oldNameTitle":20,"oldOrganization":20},"SPONSOR","100515257","evolution-of-pet-fixation-with-fdg-at-the-end-of-antibiotic-treatment-of-infective-endocarditis-on-valvular-prosthesis-100515257",false,"NCT05989152","Evolution of PET Fixation With FDG at the End of Antibiotic Treatment of Infective Endocarditis on Valvular Prosthesis","Evolution of Positron Emission Computed Tomography (PET) Fixation With Fluorodeoxyglucose (FDG) at the End of Antibiotic Treatment of Infective Endocarditis on Valvular Prosthesis","EndEOTEP","\"Inclusion criteria:\n\n* Patient aged 18 or over;\n* Have a prosthetic valve implanted surgically or by catheter for at least 3 months;\n* Presenting a definite IE on a prosthetic valve (ESC definition in force);\n* Having benefited from an FDG-PET examination for diagnostic purposes as part of the treatment revealing pathological hyperuptake at the level of the prosthetic valve AND carried out \\\u003C15 days after the start of antibiotic therapy for infective endocarditis;\n* Absence of cardiac surgical intervention performed for the current episode of AE or planned before the end-of-treatment FDG-PET\n\nExclusion criteria:\n\n* Patient under legal protection, guardianship or curators;\n* Pregnancy, breastfeeding;\n* Patient not affiliated to a health insurance scheme or not a beneficiary of a social security scheme;\n* Simultaneous participation in a study on FDG-PET;\n* Absence of informed consent signed by the patient.\"","ALL","18 Years",{"count":64,"type":65},50,"ESTIMATED","INTERVENTIONAL",[68],"NA","In patients with prosthetic valve endocarditis (PVE) and pathological valvular FDG uptake on the initial FDG-PET and not referred to valve replacement at the acute phase, the study will assess whether FDG-PET is able to identify those at increased risk of PVE relapse.",[71],"Prosthetic Valve Endocarditis",[73,74,75],"Infective endocarditis","end of treatment","Positron emission tomography","2025-07-31",{"date":78,"type":79},"2025-08-05","ACTUAL",{"date":81,"type":79},"2025-04-17",{"date":83,"type":65},"2027-12",{"name":5,"class":6},1]