[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100579040":3},{"organization":4,"armGroups":7,"interventions":15,"overallOfficials":26,"centralContacts":34,"locations":43,"responsibleParty":61,"collaborators":64,"id":68,"slug":69,"hasResults":70,"nctId":71,"briefTitle":72,"officialTitle":73,"acronym":21,"eligibilityCriteria":74,"healthyVolunteers":75,"sex":76,"minAge":77,"maxAge":78,"enrollmentInfo":79,"targetDuration":21,"studyType":82,"phases":83,"briefSummary":85,"conditions":86,"keywords":21,"overallStatus":46,"whyStopped":21,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":97},{"fullName":5,"class":6},"Penn State University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"People with ALS and their caregivers","EXPERIMENTAL","People with ALS and their caregivers will participate in structured communicative interaction.",[13,14],"Behavioral: Structured Communicative Interaction","Behavioral: Unstructured communicative interaction",[16,22],{"type":17,"name":18,"description":19,"armGroupLabels":20,"otherNames":21},"BEHAVIORAL","Structured Communicative Interaction","Two interlocutors, one with ALS and their caregiver will work together. Each participant in the pair will view the same set of words on their screens. After one second, one of the words will be highlighted on the speaker's screen, they will say the word in the phrase \"Click on the \\_\\_\\_\\_ this time\", and the listener will click on it. After the listener has made their selection, both participants will receive feedback on trial success.",[9],null,{"type":17,"name":23,"description":24,"armGroupLabels":25,"otherNames":21},"Unstructured communicative interaction","Two interlocutors, one with ALS and their caregiver will work together. The pairs will be presented with two different versions of the same picture with eight differences chosen to elicit the same target segments (e.g., \"hid\", \"ship\", \"net\"). These pictures will be modified from the LUCID corpus. In total, pairs will complete four picture sets per session. Pairs will be given 5 minutes for each picture set.",[9],[27,30,32],{"name":28,"affiliation":5,"role":29},"Jimin Lee, Ph.D.","PRINCIPAL_INVESTIGATOR",{"name":31,"affiliation":5,"role":29},"Anne Olmstead, Ph.D.",{"name":33,"affiliation":5,"role":29},"Navin Viswanathan, Ph.D.",[35,39],{"name":31,"role":36,"phone":37,"phoneExt":21,"email":38},"CONTACT","814-867-3373","ajo150@psu.edu",{"name":40,"role":36,"phone":41,"phoneExt":21,"email":42},"Navin Viswanathan, Ph.D","814-867-2340","nxv175@psu.edu",[44],{"facility":45,"status":46,"city":47,"state":48,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"Speech Core, Pennsylvania State University","RECRUITING","University Park","Pennsylvania","16802","United States","US",{"type":53,"coordinates":54},"Point",[55,56],-77.85639,40.80201,{"lat":56,"lon":55},[59],{"name":28,"role":36,"phone":37,"phoneExt":21,"email":60},"jxl91@psu.edu",{"type":29,"investigatorFullName":62,"investigatorTitle":63,"investigatorAffiliation":5,"oldNameTitle":21,"oldOrganization":21},"Ji Min Lee, Ph.D.","Associate Professor",[65],{"name":66,"class":67},"National Institute on Deafness and Other Communication Disorders (NIDCD)","NIH","100579040","examining-interactions-between-pals-and-caregivers-100579040",false,"NCT06819124","Examining Interactions Between PALS and Caregivers","Examining Interactions Between Persons With ALS and Caregivers","Inclusion Criteria:\n\nSpeakers with amyotrophic lateral sclerosis (ALS) (PALS-people with ALS)\n\n* diagnosis of ALS following the revised EL Escorial criteria\n* no history of other neurological conditions (e.g., stroke)\n* no cognitive impairment assessed by Telephone Montreal Cognitive Assessment (mini MoCA)\n* detectable speech disturbance according to the ALS Functional Rating Scale-Revised (ALSFRS-R)\n* the ability to produce single words\n* being a native speaker of American English (AE).\n\nCaregivers\n\n* being a caregiver of a participant with ALS\n* being a native speaker of American English (AE).\n\nExclusion Criteria:\n\n\\- None - if volunteer meets the inclusion criteria, then they will be enrolled",true,"ALL","18 Years","90 Years",{"count":80,"type":81},152,"ESTIMATED","INTERVENTIONAL",[84],"NA","The goal of this clinical trial is to learn about the effect of communicative interaction on verbal communication in people with amyotrophic lateral sclerosis (ALS) and their caregivers.\n\nThe question is, What are the effects of communicative interaction on verbal communication in people with ALS when they interact with their caregivers and does this change over time?\n\nParticipants will read words and sentences while they are interacting with their caregivers.",[87],"Amyotrophic Lateral Sclerosis (ALS)","2026-04-01",{"date":90,"type":91},"2026-04-06","ACTUAL",{"date":93,"type":91},"2025-01-22",{"date":95,"type":81},"2029-02-28",{"name":5,"class":6},1]