[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100573673":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":32,"centralContacts":41,"locations":49,"responsibleParty":64,"collaborators":25,"id":67,"slug":68,"hasResults":69,"nctId":70,"briefTitle":71,"officialTitle":72,"acronym":25,"eligibilityCriteria":73,"healthyVolunteers":69,"sex":74,"minAge":75,"maxAge":76,"enrollmentInfo":77,"targetDuration":25,"studyType":80,"phases":81,"briefSummary":83,"conditions":84,"keywords":89,"overallStatus":95,"whyStopped":25,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":105},{"fullName":5,"class":6},"Bahçeşehir University","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Face-to-face Exercise Group","EXPERIMENTAL","Participants will undergo exercise sessions 3 days a week for 12 weeks. Sessions will include a warm-up, upper and lower extremity strengthening (1\u002F3 set - 8\u002F12 repetitions) and cool-down program. Theraband will be used in strengthening exercises. Theraband offers different resistance levels with its different colors. In order from lightest to heaviest; skin color, yellow, red, green, blue, black, grey, gold. Exercises (theraband color, intensity, number of sets and repetitions) will be made into a personalized program according to the tolerance level of the participants in the first session. Exercise intensity will be determined using the OMNI - Resistance Exercise Scale (OMNI - RES). The warm-up and cool-down periods in the exercise program will be carried out at levels 9 - 12 according to the Borg Scale.",[13,14],"Other: Assigned Interventions","Other: Face-to-face Exercise",{"label":16,"type":10,"description":17,"interventionNames":18},"Home-based Exercise Group","Participants will follow the same program as in the face-to-face exercise group. The first meeting with the participants will be held face to face and the details of the study will be explained. Home-based exercises will be carried out with the Fiziu (Fiziu Sağlık Hizmetleri Teknoloji A.Ş., Istanbul, Türkiye) program and the exercise program will be delivered to the participants through this program. Therabands with which the participants will do their exercises will be provided by the researchers. The progression program will be determined in line with the difficulty and effort felt by the participants through weekly meetings.",[13,19],"Other: Home-based Exercise",[21,26,29],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"Assigned Interventions","Psychometric Hepatic Encephalopathy Scoring (PHES) Test\n\n* Digit Symbol Test\n* Number Combination Test-A\n* Number Combination Test-B\n* Serial Punctuation Test\n* Line Drawing Test\n\n  6 Minute Walk Test\n\n  5 Times Sit and Stand Test\n\nManual Muscle Test\n\nHand Grip Strength Test\n\nQuadriceps muscle thickness measurement with ultrasonography\n\nAll evaluations will be repeated 5 times.",[9,16],null,{"type":6,"name":27,"description":11,"armGroupLabels":28,"otherNames":25},"Face-to-face Exercise",[9],{"type":6,"name":30,"description":17,"armGroupLabels":31,"otherNames":25},"Home-based Exercise",[16],[33,37],{"name":34,"affiliation":35,"role":36},"Pelin Pişirici","Bahcesehir University, Department of Physiotherapy and Rehabilitation","STUDY_DIRECTOR",{"name":38,"affiliation":39,"role":40},"Mustafa Oğuz Kethüdaoğlu","Sivas Cumhuriyet University,Department of Physiotherapy and Rehabilitation \u002F\u002F Bahçeşehir University, Doctorate Program of Physiotherapy and Rehabilitation","PRINCIPAL_INVESTIGATOR",[42,46],{"name":38,"role":43,"phone":44,"phoneExt":25,"email":45},"CONTACT","+905544169776","mustafaoguzkethudaoglu@gmail.com",{"name":34,"role":43,"phone":47,"phoneExt":25,"email":48},"+905055016076","pelinpisirici@gmail.com",[50],{"facility":51,"status":25,"city":52,"state":25,"zip":53,"country":54,"countryCode":25,"cosmosGeoPoint":55,"geoPoint":60,"contacts":61},"Sivas Cumhuriyet University","Sivas","58140","Turkey (Türkiye)",{"type":56,"coordinates":57},"Point",[58,59],37.01611,39.74833,{"lat":59,"lon":58},[62,63],{"name":38,"role":43,"phone":44,"phoneExt":25,"email":45},{"name":38,"role":40,"phone":25,"phoneExt":25,"email":25},{"type":40,"investigatorFullName":65,"investigatorTitle":66,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Mustafa Oğuz Kethudaoglu","Pirincipal Investigator; PT, MSc, PhD (c)","100573673","examining-the-effects-of-different-resistive-exercise-programs-in-individuals-with-compensated-liver-cirrhosis-100573673",false,"NCT06749340","Examining the Effects of Different Resistive Exercise Programs in Individuals With Compensated Liver Cirrhosis","Examination of the Effects of Face-to-Face and Home-Based Resistive Exercise Program on Muscle Strength, Muscle Mass and Cognitive Functions in Individuals With Compensated Liver Cirrhosis: Randomized Controlled Single -Blind Study","Inclusion Criteria:\n\n* Being between the ages of 40 and 65;\n* Being diagnosed with liver cirrhosis;\n* Not having had a liver transplant;\n* Being cooperative;\n* Volunteering to participate in the study;\n* Having a smart device (phone\u002Ftablet\u002Fcomputer);\n* Having internet access;\n* Modified Child-Turcotte-Pugh Score to be A and B.\n\nExclusion Criteria:\n\n* Having a disease that may affect cognitive functions;\n* Having an orthopedic, neurological, psychological, cardiac, renal or pulmonary disease;\n* Having a physical or mental disability;\n* Having a communication problem;\n* Being unable to read or write;\n* Modified Child-Turcotte-Pugh Score to be C.","ALL","40 Years","65 Years",{"count":78,"type":79},20,"ESTIMATED","INTERVENTIONAL",[82],"NA","Reasons such as sleep disorders, depression, decreased independence in daily living activities and decreased quality of life, which are seen in the majority of liver cirrhosis patients, can cause cognitive dysfunction, especially attention. It is known that physical dysfunctions are observed in patients with liver cirrhosis along with cognitive dysfunction. Sarcopenia is the most important of these dysfunctions. Sarcopenia is the progressive, widespread loss of muscle mass, function and strength. The aim of this study is to determine the effects of face-to-face and home-based progressive strengthening exercise program performed 3 times a week for 12 weeks on muscle strength, muscle mass, functionality and cognitive functions in individuals with liver cirrhosis. It is also aimed to test the feasibility and effectiveness of the home-based exercise method in individuals with liver cirrhosis. Another aim of our study is to determine the exercise dose required to improve muscle strength, muscle mass, functionality and cognitive functions in individuals with liver cirrhosis and the duration of treatment effectiveness through follow-up.",[85,86,87,88],"Coginitive Dysfunction","Compensated Liver Cirrhosis","Physical Dysfunction","Sarcopenia",[90,91,92,93,94],"cirrhosis","cognitive dysfunction","sarcopenia","strengthening","telerehabilitation","NOT_YET_RECRUITING","2026-02-18",{"date":98,"type":99},"2026-02-20","ACTUAL",{"date":101,"type":79},"2026-02-19",{"date":103,"type":79},"2026-12-23",{"name":5,"class":6},1]