[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100432840":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":30,"centralContacts":34,"locations":39,"responsibleParty":53,"collaborators":25,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":59,"acronym":25,"eligibilityCriteria":60,"healthyVolunteers":61,"sex":62,"minAge":63,"maxAge":64,"enrollmentInfo":65,"targetDuration":25,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":74,"overallStatus":41,"whyStopped":25,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"Virginia Commonwealth University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Muscular Strength","EXPERIMENTAL","Participants will complete study 1 (HM20020955-1) and then 10 weeks of resistance training for muscular strength",[13],"Behavioral: Muscular Strength Training Group",{"label":15,"type":10,"description":16,"interventionNames":17},"Muscular fitness","Participants will complete study 1 (HM20020955-1) and then 10 weeks of resistance training for muscular fitness",[18],"Behavioral: Muscular Fitness Training Group",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","Muscular Strength Training Group","Week 1 3 days\u002Fweek Bench Press - 1 set at 80% of one repetition maximum\n\n(1RM) Bent Over Row - 1 set at 80% 1RM Back Squat - 1 set at 80% 1RM Romanian Deadlift - 1 set at 80% 1RM\n\nWeek 2 3 days\u002Fweek Bench Press - 2 sets at 80% 1RM Bent Over Row - 2 sets at 80% 1RM Back Squat - 2 sets at 80% 1RM Romanian Deadlift - 2 sets at 80% 1RM\n\nWeeks 3-10 3 days\u002Fweek Bench Press - 3 sets at 80% 1RM Bent Over Row - 3 sets at 80% 1RM Back Squat - 3 sets at 80% 1RM Romanian Deadlift - 3 sets at 80% 1RM",[9],null,{"type":21,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Muscular Fitness Training Group","Week 1 3 days\u002Fweek Bench Press - 1 set at 65% 1RM Bent Over Row - 1 set at 65% 1RM Back Squat - 1 set at 65% 1RM Romanian Deadlift - 1 set at 65% 1RM\n\nWeek 2 3 days\u002Fweek Bench Press - 2 sets at 65% 1RM Bent Over Row - 2 sets at 65% 1RM Back Squat - 2 sets at 65% 1RM Romanian Deadlift - 2 sets at 65% 1RM\n\nWeeks 3-10 3 days\u002Fweek Bench Press - 3 sets at 65% 1RM Bent Over Row - 3 sets at 65% 1RM Back Squat - 3 sets at 65% 1RM Romanian Deadlift - 3 sets at 65% 1RM",[15],[31],{"name":32,"affiliation":5,"role":33},"Ryan Garten, PhD","PRINCIPAL_INVESTIGATOR",[35],{"name":32,"role":36,"phone":37,"phoneExt":25,"email":38},"CONTACT","(804) 828-1948","rsgarten@vcu.edu",[40],{"facility":5,"status":41,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":25},"RECRUITING","Richmond","Virginia","23298","United States","US",{"type":48,"coordinates":49},"Point",[50,51],-77.46026,37.55376,{"lat":51,"lon":50},{"type":54,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100432840","examining-the-impact-of-exercise-training-on-vascular-dysfunction-in-individuals-with-mental-health-disorders---study-3-100432840",false,"NCT04916340","Examining the Impact of Exercise Training on Vascular Dysfunction in Individuals With Mental Health Disorders - Study 3","Inclusion Criteria:\n\n* apparently healthy and free of overt cardiovascular, pulmonary, or metabolic disease\n* for PTSD group, a score of ≥ 33 on PCL-5 checklist\n* for GAD group, a score of ≥ 10 on the GAD-7 self-report scale and \\\u003C 33 on the PCL-5 checklist\n* for Healthy Control group, a score of ≤ 10 on the GAD-7 self-report scale and \\\u003C 33 on the PCL-5 checklist\n\nExclusion Criteria:\n\n* taking medications that could influence cardiovascular function\n* current smokers who have recently quit smoking\n* illicit drug use or excessive alcohol consumption\n* pregnant women\n* significant calorie restriction or vitamin\u002Fmineral deficiencies\n* limited English proficiency",true,"ALL","18 Years","35 Years",{"count":66,"type":67},240,"ESTIMATED","INTERVENTIONAL",[70],"NA","The purpose of this research study is to examine the effect of various forms of exercise training on blood vessel function in healthy individuals as well as individuals with mental health disorders (posttraumatic stress disorder (PTSD) and\u002For generalized anxiety disorder (GAD)).",[73],"Peripheral Vascular Diseases",[75,76,77,78,79],"cardiovascular disease","vascular function","PTSD","GAD","Oxidant","2026-03-30",{"date":82,"type":83},"2026-04-01","ACTUAL",{"date":85,"type":83},"2022-01-24",{"date":87,"type":67},"2026-12-28",{"name":5,"class":6},1]