[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100613342":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":25,"centralContacts":29,"locations":38,"responsibleParty":57,"collaborators":24,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":24,"eligibilityCriteria":67,"healthyVolunteers":68,"sex":69,"minAge":24,"maxAge":24,"enrollmentInfo":70,"targetDuration":24,"studyType":73,"phases":74,"briefSummary":76,"conditions":77,"keywords":80,"overallStatus":41,"whyStopped":24,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"Saint Thomas Hospital, Panama","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Severe preeclampsia","EXPERIMENTAL","Pregnant subjects with severe preeclampsia",[13],"Diagnostic Test: Arterial Blood gases",{"label":15,"type":10,"description":16,"interventionNames":17},"Normotensive","Pregnant subjects with normal blood pressure",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"DIAGNOSTIC_TEST","Arterial Blood gases","Determination of Excess Base in arterial blood gases before delivery \u002F termination of pregnancy",[15,9],null,[26],{"name":27,"affiliation":5,"role":28},"Osvaldo Reyes, MD","STUDY_CHAIR",[30,35],{"name":31,"role":32,"phone":33,"phoneExt":24,"email":34},"Francisco Jordan, MD","CONTACT","+507 6983-0029","fcojordan19@gmail.com",{"name":36,"role":32,"phone":24,"phoneExt":24,"email":37},"Adriana Martinz, MD","amartinzmd@gmail.com",[39],{"facility":40,"status":41,"city":42,"state":43,"zip":24,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Saint Thomas Hospital","RECRUITING","Panama City","Provincia de Panamá","Panama","PA",{"type":47,"coordinates":48},"Point",[49,50],-79.51973,8.9936,{"lat":50,"lon":49},[53],{"name":54,"role":32,"phone":55,"phoneExt":24,"email":56},"Osvaldo A Reyes, MD","o11(507)65655041","oreyespanama@yahoo.es",{"type":58,"investigatorFullName":59,"investigatorTitle":60,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"PRINCIPAL_INVESTIGATOR","Osvaldo A. Reyes T.","Head of Research Department","100613342","excess-base-comparison-between-pregnant-subjects-with-severe-preeclampsia-vs-normotensive-pregnant-women-100613342",false,"NCT07265336","Excess Base Comparison Between Pregnant Subjects With Severe Preeclampsia vs. Normotensive Pregnant Women","Comparison of Base Excess in Arterial Blood Gases Between Patients With Severe Preeclampsia and Normotensive Pregnant Patients","Inclusion Criteria:\n\n* Gestational age: 24-40 weeks\n* Cases: Diagnosis of severe preeclampsia\n* Control: Normal blood pressure\n\nExclusion Criteria:\n\n* Metabolic conditions that could hinder the results (diabetic ketoacidosis, sepsis, renal failure).\n* Clinical conditions that could hinder the results (diarrhea, vomit)\n* Recent use of bicarbonate",true,"FEMALE",{"count":71,"type":72},100,"ESTIMATED","INTERVENTIONAL",[75],"NA","The study's primary goal is to compare the base excess (BE) values-an indicator of metabolic changes-in two groups of patients at Santo Tomás Hospital: those with severe preeclampsia and healthy, pregnant individuals. Researchers will measure these values using an arterial blood gas test before delivery or surgery.\n\nThis is a prospective cohort study. The researchers will analyze various blood gas parameters, including pH, lactate, and BE, and then correlate the BE values with clinical variables and negative maternal outcomes.\n\nThe expected outcome is that a abnormal BE values will be linked to a greater severity of preeclampsia. If this association is confirmed, BE could serve as an additional marker for predicting the severity of the condition and may lay the groundwork for future research on diagnostic and therapeutic standards based on blood gas analysis.",[78,79],"Preeclampsia","Severe Preeclampsia",[81,9,82],"Excess base","Arterial blood gases","2025-12-02",{"date":85,"type":86},"2025-12-04","ACTUAL",{"date":88,"type":86},"2025-08-15",{"date":90,"type":72},"2026-01-31",{"name":5,"class":6},1]