[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100562803":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":23,"centralContacts":28,"locations":37,"responsibleParty":76,"collaborators":18,"id":78,"slug":79,"hasResults":80,"nctId":81,"briefTitle":82,"officialTitle":83,"acronym":84,"eligibilityCriteria":85,"healthyVolunteers":80,"sex":86,"minAge":87,"maxAge":18,"enrollmentInfo":88,"targetDuration":18,"studyType":91,"phases":92,"briefSummary":94,"conditions":95,"keywords":18,"overallStatus":39,"whyStopped":18,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":98,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":105,"locationsCount":106},{"fullName":5,"class":6},"VA Office of Research and Development","FED",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Exercise","EXPERIMENTAL","The participants will exercise 2 days a week for 16 weeks. The exercises will include 4 movements: squats, shoulder press, seated row, and bicep curl focusing on internal load and contraction velocity.",[13],"Other: Exercise",{"label":15,"type":16,"description":17,"interventionNames":18},"Usual Care","NO_INTERVENTION","Participants will not have any study intervention visits for usual care.",null,[20],{"type":21,"name":9,"description":11,"armGroupLabels":22,"otherNames":18},"OTHER",[9],[24],{"name":25,"affiliation":26,"role":27},"Michael Harris-Love, DSc MPT BS","Rocky Mountain Regional VA Medical Center, Aurora, CO","PRINCIPAL_INVESTIGATOR",[29,33],{"name":25,"role":30,"phone":31,"phoneExt":18,"email":32},"CONTACT","(720) 857-2802","MICHAEL.HARRIS-LOVE@CUANSCHUTZ.EDU",{"name":34,"role":30,"phone":35,"phoneExt":18,"email":36},"Katie Boncella, MS","(303) 724-0687","katie.boncella@va.gov",[38,56],{"facility":26,"status":39,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"RECRUITING","Aurora","Colorado","80045-7211","United States","US",{"type":46,"coordinates":47},"Point",[48,49],-104.83192,39.72943,{"lat":49,"lon":48},[52,54,55],{"name":34,"role":30,"phone":53,"phoneExt":18,"email":36},"303-724-0687",{"name":25,"role":30,"phone":31,"phoneExt":18,"email":32},{"name":25,"role":27,"phone":18,"phoneExt":18,"email":18},{"facility":57,"status":39,"city":58,"state":59,"zip":60,"country":43,"countryCode":44,"cosmosGeoPoint":61,"geoPoint":65,"contacts":66},"Baltimore VA Medical Center VA Maryland Health Care System, Baltimore, MD","Baltimore","Maryland","21201",{"type":46,"coordinates":62},[63,64],-76.61219,39.29038,{"lat":64,"lon":63},[67,72],{"name":68,"role":30,"phone":69,"phoneExt":70,"email":71},"Rhianna Patel, MS","410-605-7000","55393","rhianna.patel@va.gov",{"name":73,"role":30,"phone":74,"phoneExt":70,"email":75},"Odessa Addison, PhD","4106057000","odessa.addison@va.gov",{"type":77,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR","100562803","exercise-and-monitoring-with-post-hospitalization-muscle-atrophy-to-sustain-intrinsic-capacity-and-strength-100562803",false,"NCT06607913","Exercise and Monitoring With Post-Hospitalization Muscle Atrophy to Sustain Intrinsic Capacity and Strength","BCCMA: Recovery of Aged Muscle After Disuse Atrophy (REMEDY): Exercise and Monitoring With Post-Hospitalization Muscle Atrophy to Sustain Intrinsic Capacity and Strength (EMPHASIS)","EMPHASIS","Inclusion Criteria:\n\n* Age \\> 55 years\n* Diagnosis of stage 3-4 CKD or an eGFR of \\\u003C45 mL\u002Fmin\u002F1.73m2\n\nExclusion Criteria:\n\n* Cardiovascular risk: Poorly controlled hypertension (\\>160\u002F100)\n\n  * Coronary event in past 6 months\n  * Class III or IV CHF\n  * symptomatic angina at rest or during exercise\n  * Syncope in past year, without known resolution of cause\n* COPD requiring home oxygen\n* Contraindications to resistance training, including history of intracranial or retinal bleeding; Diabetes with active proliferative retinopathy\n* History of significant spinal osteoarthritis or spinal stenosis\n* Dementia (on medical record review or mini-mental status exam score)","ALL","55 Years",{"count":89,"type":90},250,"ESTIMATED","INTERVENTIONAL",[93],"NA","The aging Veteran population has more frequent inpatient hospitalization than non-Veterans. In addition, older Veterans have an inability to fully recover muscle mass and function after hospital-acquired weakness. The problem of hospital-acquired weakness is greatly increased in at-risk Veteran populations such as those with chronic kidney disease (CKD). The purpose of this collaborative study involving Denver and Baltimore VAMC sites is to improve health through the detection and rehabilitation management of hospital-acquired weakness in those with CKD. The study goals include identifying and monitoring the optimal muscle assessment sites in clinical settings, examining how muscle health impacts length of hospital stay and physical resilience, and determining how home-based and supervised exercise comparatively addresses post-hospitalization physical resilience using performance tests and Veteran feedback.",[96],"Chronic Kidney Disease (CKD)","2026-03-31",{"date":99,"type":100},"2026-04-07","ACTUAL",{"date":102,"type":100},"2025-04-11",{"date":104,"type":90},"2029-09-30",{"name":5,"class":6},2]