[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100439038":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":28,"centralContacts":32,"locations":37,"responsibleParty":61,"collaborators":24,"id":63,"slug":64,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":67,"acronym":24,"eligibilityCriteria":68,"healthyVolunteers":65,"sex":69,"minAge":70,"maxAge":24,"enrollmentInfo":71,"targetDuration":24,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":86,"overallStatus":40,"whyStopped":24,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":99},{"fullName":5,"class":6},"Dana-Farber Cancer Institute","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Exercise","EXPERIMENTAL","Participants randomized to one of two groups with 2:1 ratio: exercise (n=20)\n\n\\- Aerobic and Resistance Exercise for 16 weeks",[13],"Other: Exercise",{"label":15,"type":16,"description":17,"interventionNames":18},"Attention Control","ACTIVE_COMPARATOR","Participants randomized to one of two groups with attention control (n=10).\n\n-Attention Control for 16 weeks home-based stretching",[19],"Other: Attention Control",[21,25],{"type":6,"name":9,"description":22,"armGroupLabels":23,"otherNames":24},"16-week, virtually supervised, technology-based, aerobic and resistance exercise program performed 3 days per week which starts at least 4 weeks after surgery",[9],null,{"type":6,"name":15,"description":26,"armGroupLabels":27,"otherNames":24},"Home-based stretching program consisting of one set of 4 static stretching exercises held for 30 seconds and performed 3 days\u002Fweek. Participants will be shown how to use the booklet and instructed on how to complete the stretching exercises by an exercise trainer.",[15],[29],{"name":30,"affiliation":5,"role":31},"Christina Dieli-Conwright, PhD","PRINCIPAL_INVESTIGATOR",[33],{"name":30,"role":34,"phone":35,"phoneExt":24,"email":36},"CONTACT","(617) 582-8321","ChristinaM_Dieli-Conwright@dfci.harvard.edu",[38],{"facility":39,"status":40,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Dana Farber Cancer Institute","RECRUITING","Boston","Massachusetts","02215","United States","US",{"type":47,"coordinates":48},"Point",[49,50],-71.05977,42.35843,{"lat":50,"lon":49},[53,56,60],{"name":54,"role":34,"phone":55,"phoneExt":24,"email":36},"Christina Dieli-Conwright, PhD, MPH","617-582-8321",{"name":57,"role":34,"phone":58,"phoneExt":24,"email":59},"Mary Norris, MS","857-215-0195","maryk_norris@dfci.harvard.edu",{"name":30,"role":31,"phone":24,"phoneExt":24,"email":24},{"type":31,"investigatorFullName":30,"investigatorTitle":62,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"Principal Investigator","100439038","exercise-as-a-preventive-agent-to-combat-immobility-in-patients-with-ovarian-or-endometrial-cancers-receiving-chemotherapy-100439038",false,"NCT04997096","Exercise as a Preventive Agent to Combat Immobility in Patients With Ovarian or Endometrial Cancers Receiving Chemotherapy","Inclusion Criteria:\n\n* Newly diagnosed patients with stages III-IV ovarian or endometrial cancer\n* Receiving first-line carboplatin and paclitaxel chemotherapy after surgery\n* ≥18 years, children under the age of 18 will be excluded due to rarity of disease\n* Physician's clearance to participate in moderate-vigorous intensity exercise\n* Able to read, write, and understand English\n* Ability to understand and the willingness to sign an informed consent document\n* Willing to undergo two venous blood draws for the study\n\nExclusion Criteria:\n\n* Pre-existing musculoskeletal, neurological, or cardiorespiratory conditions, as determined by the treating oncologist\n* Participants with uncontrolled intercurrent illness, as determined by the treating oncologist\n* Participants with psychiatric illness\u002Fsocial situations that would limit compliance with study requirements, as determined by the treating oncologist\n* Participants who have received prior chemotherapy for cancer treatment (e.g. taxanes for breast cancer)","FEMALE","18 Years",{"count":72,"type":73},30,"ESTIMATED","INTERVENTIONAL",[76],"NA","The purpose of this research is to determine whether a 16-week virtually supervised aerobic and resistance exercise program is feasible in patients receiving first-line chemotherapy after surgery for ovarian or endometrial cancer and if it will improve lower extremity function (function of the legs), lessen chemotherapy-induced peripheral neuropathy (CIPN; numbness or tingling in the hands or feet), and if there is any effect on inflammatory blood markers (the level of a certain marker in the blood that is associated with inflammation; redness and swelling).",[79,80,81,82,83,84,85],"Ovarian Cancer","Ovarian Carcinoma","Ovarian Cancer Stage IV","Ovarian Cancer Stage III","Ovarian Cancer Stage 3","Endometrial Cancer","Endometrial Cancer Stage",[79,80,81,82,83,84,87,88,89],"Aerobic Exercise","Strength Training","Cardiovascular training","2026-02-17",{"date":92,"type":93},"2026-02-19","ACTUAL",{"date":95,"type":93},"2022-04-02",{"date":97,"type":73},"2029-04-30",{"name":5,"class":6},1]