[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100606934":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":26,"locations":32,"responsibleParty":52,"collaborators":25,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":25,"eligibilityCriteria":62,"healthyVolunteers":63,"sex":64,"minAge":65,"maxAge":66,"enrollmentInfo":67,"targetDuration":25,"studyType":70,"phases":71,"briefSummary":73,"conditions":74,"keywords":78,"overallStatus":84,"whyStopped":25,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"Boston Children's Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Youth with Chronic Pain Syndromes","EXPERIMENTAL","Youth with chronic pain will undergo quantitative sensory testing before and immediately after a single bout of intense aerobic exercise.",[13],"Behavioral: Aerobic Exercise",{"label":15,"type":16,"description":17,"interventionNames":18},"Youth without Chronic Pain Syndromes","ACTIVE_COMPARATOR","Youth without chronic pain will undergo quantitative sensory testing before and immediately after a single bout of intense aerobic exercise. They will serve as a control group to determine if the intervention has different effects between groups.",[13],[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","Aerobic Exercise","Submaximal cardiovascular endurance testing on a treadmill",[9,15],null,[27],{"name":28,"role":29,"phone":30,"phoneExt":25,"email":31},"Julie Shulman, PhD, DPT","CONTACT","781-216-1650","julie.shulman@childrens.harvard.edu",[33],{"facility":34,"status":25,"city":35,"state":36,"zip":37,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"Boston Children's Hospital at 2 Brookline Place","Brookline","Massachusetts","02445","United States","US",{"type":41,"coordinates":42},"Point",[43,44],-71.12116,42.33176,{"lat":44,"lon":43},[47,49],{"name":48,"role":29,"phone":30,"phoneExt":25,"email":31},"Julie Shulman, PT, DPT, PhD, PCS",{"name":50,"role":29,"phone":30,"phoneExt":25,"email":51},"Avery Savage, BS","avery.savage@childrens.harvard.edu",{"type":53,"investigatorFullName":54,"investigatorTitle":55,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Julie Shulman","Physical Therapy Scientist","100606934","exercise-as-medicine-for-pediatric-chronic-pain-100606934",false,"NCT07182006","Exercise as Medicine for Pediatric Chronic Pain","Movement as Medicine: Can a Single Bout of Aerobic Exercise Elicit Exercise-induced Hypoalgesia in Youth With and Without Chronic Pain Syndromes?","Inclusion Criteria:\n\n* Primary or secondary chronic pain syndrome\n\nExclusion Criteria:\n\n* Allodynia (pain with light touch) at testing sites (non-dominant forearm)\n* Self-reported use of opioids in last week\n* Comorbid condition for which exercise is deemed unsafe by a physician or the (Physical Activity Readiness Questionnaire+) PARQ+\n* unable to safely ambulate on a treadmill",true,"ALL","10 Years","17 Years",{"count":68,"type":69},66,"ESTIMATED","INTERVENTIONAL",[72],"NA","Youth with chronic pain struggle to go to school, play sports, or spend time with friends and family due to pain. Medications are often ineffective, and aerobic exercise may improve both pain sensitivity and participation in valued life activities. This study will be the first to examine the impact of a single session of intense aerobic exercise on pain sensitivity measures in youth with and without chronic pain syndromes to help determine if aerobic exercise can improve pain and functioning.",[75,76,77],"Chronic Pain","Child","Adolescent",[79,80,81,82,83],"aerobic exercise","chronic pain","pediatric","quantitative sensory testing","endogenous pain modulation","NOT_YET_RECRUITING","2025-09-16",{"date":87,"type":88},"2025-09-19","ACTUAL",{"date":90,"type":69},"2026-04-01",{"date":92,"type":69},"2027-03-30",{"name":5,"class":6},1]