[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100425643":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":22,"centralContacts":23,"locations":29,"responsibleParty":50,"collaborators":22,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":22,"eligibilityCriteria":59,"healthyVolunteers":55,"sex":60,"minAge":61,"maxAge":62,"enrollmentInfo":63,"targetDuration":22,"studyType":66,"phases":67,"briefSummary":69,"conditions":70,"keywords":72,"overallStatus":31,"whyStopped":22,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":83},{"fullName":5,"class":6},"Korea University Anam Hospital","OTHER",[8],{"label":9,"type":6,"description":10,"interventionNames":11},"Heart failure with preserved ejection fraction","Adenosine stress echocardiography, body composition, and cardiopulmonary exercise test will be done in all of the enrolled patients. Left ventricular end-diastolic pressure will be assessed during coronary angiography.",[12],"Diagnostic Test: Adenosine stress echocardiography with the evaluation of coronary artery blood flow",[14],{"type":15,"name":16,"description":17,"armGroupLabels":18,"otherNames":19},"DIAGNOSTIC_TEST","Adenosine stress echocardiography with the evaluation of coronary artery blood flow","The color Doppler flow of distal left anterior descending artery will be examined from the modified apical four-chamber view in the anterior interventricular groove.\n\nIn regard to body composition analysis, Using InBody S10, impedance is measured in 6 frequency bands (1 kilohertz (kHz), 5 kHz, 50 kHz, 250 kHz, 500 kHz, 1000 kHz) for each of 5 parts (right plate, left arm, torso, right leg, left leg). Reactance is measured in 3 frequency bands (5 kHz, 50 kHz, 250 kHz for each of 5 parts (right arm, left arm, torso, right leg, left leg).\n\nBy treadmill exercise test with modified Bruce protocol or bicycle ergometer for patients with orthopedic problems, maximal oxygen consumption (VO2 max) will be measured using the exhalation gas analysis.",[9],[20,21],"Body composition analysis","Cardiopulmonary exercise test",null,[24],{"name":25,"role":26,"phone":27,"phoneExt":22,"email":28},"So Ree Kim, MD","CONTACT","821094534810","soree8826kim@gmail.com",[30],{"facility":5,"status":31,"city":32,"state":22,"zip":22,"country":33,"countryCode":22,"cosmosGeoPoint":34,"geoPoint":39,"contacts":40},"RECRUITING","Seoul","South Korea",{"type":35,"coordinates":36},"Point",[37,38],126.9784,37.566,{"lat":38,"lon":37},[41,42,45,48],{"name":25,"role":26,"phone":22,"phoneExt":22,"email":28},{"name":43,"role":44,"phone":22,"phoneExt":22,"email":22},"Seong-Mi Park","PRINCIPAL_INVESTIGATOR",{"name":46,"role":47,"phone":22,"phoneExt":22,"email":22},"Mi-Na Kim","SUB_INVESTIGATOR",{"name":49,"role":47,"phone":22,"phoneExt":22,"email":22},"So Ree Kim",{"type":44,"investigatorFullName":51,"investigatorTitle":52,"investigatorAffiliation":5,"oldNameTitle":22,"oldOrganization":22},"Seong-Mi Park, M.D. Ph.D.","Professor","100425643","exercise-capacity-according-to-coronary-microvascular-dysfunction-and-body-composition-100425643",false,"NCT04822649","Exercise Capacity According to Coronary Microvascular Dysfunction and Body Composition","Differences in Cardiopulmonary Exercise Capacity According to Coronary Microvascular Dysfunction and Body Composition in Patients With Suspected Heart Failure With Preserved Ejection Fraction","Inclusion Criteria:\n\n* Age 20 to 80\n* Typical\u002Fatypical chest pain or ischemic symptoms including dyspnea\n* No significant coronary artery stenosis (\\>50% stenosis) in coronary angiography or computed tomography\n* Left ventricular ejection fraction ≥50%\n\nExclusion Criteria:\n\n* More than moderate valvular heart disease\n* Congenital heart disease\n* Chronic renal failure (estimated glomerular filtration rate \\\u003C30 ml\u002Fmin\u002F1.73m2) or end-stage renal failure undergoing hemodialysis or peritoneal dialysis\n* Asthma, chronic obstructive pulmonary disease and primary pulmonary hypertension\n* Receiving anticancer drugs\n* Vasculitis associated with autoimmune diseases\n* Patients with difficulty in performing exercise load evaluation (treadmill, bicycle ergometer)\n* Atrial fibrillation\n* Atrioventricular block with more than second degrees, symptomatic bradycardia, cryo-node failure syndrome, Wolff-Parkinson-White (WPW) patients","ALL","20 Years","80 Years",{"count":64,"type":65},100,"ESTIMATED","INTERVENTIONAL",[68],"NA","The correlation of coronary microvascular function and body composition with cardiopulmonary exercise capacity will be assessed in patients with heart failure with preserved ejection fraction.",[71],"Heart Failure With Preserved Ejection Fraction (HFpEF)",[73],"body composition, CPET, CFR, coronary microvascular dysfunction (CMD), frailty, HFpEF","2025-08-25",{"date":76,"type":77},"2025-09-02","ACTUAL",{"date":79,"type":77},"2021-04-15",{"date":81,"type":65},"2025-12-31",{"name":5,"class":6},1]