[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100532437":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":44,"centralContacts":48,"locations":58,"responsibleParty":75,"collaborators":77,"id":81,"slug":82,"hasResults":83,"nctId":84,"briefTitle":85,"officialTitle":86,"acronym":87,"eligibilityCriteria":88,"healthyVolunteers":83,"sex":89,"minAge":90,"maxAge":10,"enrollmentInfo":91,"targetDuration":10,"studyType":94,"phases":10,"briefSummary":95,"conditions":96,"keywords":98,"overallStatus":60,"whyStopped":10,"lastUpdateSubmitDate":101,"lastUpdatePostDateStruct":102,"startDateStruct":105,"completionDateStruct":107,"leadSponsor":109,"locationsCount":110},{"fullName":5,"class":6},"Virginia Commonwealth University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients under going catheter ablation",null,"Patients undergoing catheter ablation for paroxysmal AF, reduction or elimination of arrhythmia burden",[13,14,15,16,17,18],"Behavioral: Self- Report Evaluation-Duke Activity Status Index","Behavioral: Self- Report Evaluation Atrial Fibrillation Effect on Quality of Life Questionnaire","Diagnostic Test: Cardiopulmonary exercise test (CPET)","Diagnostic Test: Transthoracic echocardiogram","Diagnostic Test: Ambulatory cardiac rhythm assessment","Diagnostic Test: Cardiovascular magnetic resonance (CMR)",[20,25,29,33,37,40],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":10},"BEHAVIORAL","Self- Report Evaluation-Duke Activity Status Index","Complete the Self- Report Evaluation-Duke Activity Status Index",[9],{"type":21,"name":26,"description":27,"armGroupLabels":28,"otherNames":10},"Self- Report Evaluation Atrial Fibrillation Effect on Quality of Life Questionnaire","Complete the Self- Report Evaluation, Atrial Fibrillation Effect on Quality of Life Questionnaire",[9],{"type":30,"name":31,"description":31,"armGroupLabels":32,"otherNames":10},"DIAGNOSTIC_TEST","Cardiopulmonary exercise test (CPET)",[9],{"type":30,"name":34,"description":35,"armGroupLabels":36,"otherNames":10},"Transthoracic echocardiogram","Transthoracic echocardiogram at rest and immediately following peak exercise during CPET",[9],{"type":30,"name":38,"description":38,"armGroupLabels":39,"otherNames":10},"Ambulatory cardiac rhythm assessment",[9],{"type":30,"name":41,"description":42,"armGroupLabels":43,"otherNames":10},"Cardiovascular magnetic resonance (CMR)","Cardiovascular magnetic resonance (CMR) study at rest and during two stages of submaximal exercise (ExeCMR)",[9],[45],{"name":46,"affiliation":5,"role":47},"Cory Trankle","PRINCIPAL_INVESTIGATOR",[49,54],{"name":50,"role":51,"phone":52,"phoneExt":10,"email":53},"Pamela Grizzard","CONTACT","804-628-6234","pamela.grizzard@vcuhealth.org",{"name":55,"role":51,"phone":56,"phoneExt":10,"email":57},"Melissa Sears","804-828-1601","melissa.sears@vcuhealth.org",[59],{"facility":5,"status":60,"city":61,"state":62,"zip":63,"country":64,"countryCode":65,"cosmosGeoPoint":66,"geoPoint":71,"contacts":72},"RECRUITING","Richmond","Virginia","23298","United States","US",{"type":67,"coordinates":68},"Point",[69,70],-77.46026,37.55376,{"lat":70,"lon":69},[73,74],{"name":50,"role":51,"phone":52,"phoneExt":10,"email":53},{"name":55,"role":51,"phone":56,"phoneExt":10,"email":57},{"type":76,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[78],{"name":79,"class":80},"National Heart, Lung, and Blood Institute (NHLBI)","NIH","100532437","exercise-cardiac-magnetic-resonance-assessment-of-left-atrial-mechanics-following-ablation-100532437",false,"NCT06212791","EXercise Cardiac Magnetic Resonance Assessment of Left Atrial Mechanics Following Ablation","EXCLAMATORY: EXercise Cardiac Magnetic Resonance Assessment of Left Atrial Mechanics Following Ablation TO Reduce Atrial Fibrillation Burden and Correlation With Exercise CapacitY Longitudinal Study","EXCLAMATORY","Inclusion Criteria:\n\n* Age ≥18 years\n* Diagnosis of paroxysmal AF\n* Left ventricular ejection fraction ≥50%\n* Scheduled for catheter ablation\n* Able to speak, hear, and read English\n* Willing and able to provide informed consent\n\nExclusion Criteria:\n\n* Persistent or permanent AF\n* Prior ablation (catheter based or surgical) for AF\n* Significant sinus node dysfunction\n* Implanted pacemaker or defibrillator\n* Contraindication to or inability to complete cardiovascular magnetic resonance study\n* Contraindication to or inability to complete exercise testing\n* Chronic kidney disease with estimated glomerular filtration rate \\\u003C30 mL\u002Fmin\u002F1.73m2\n* Severe left ventricular hypertrophy\n* Unrelated cardiomyopathy that is expected to limit exercise capacity, including but not limited to:\n\n  * Hypertrophic cardiomyopathy\n  * Cardiac amyloidosis\n  * Constrictive pericarditis\n* Pulmonary arterial hypertension\n* Prior cardiac surgery\n* Active pregnancy","ALL","18 Years",{"count":92,"type":93},50,"ESTIMATED","OBSERVATIONAL","Longitudinal, observational cohort study to evaluate changes in left atrial (LA) reservoir function during exercise and overall exertional capacity in patients following catheter ablation for paroxysmal atrial fibrillation (AF).",[97],"Paroxysmal Atrial Fibrillation",[99,100],"Catheter ablation","Exercise capacity","2026-03-11",{"date":103,"type":104},"2026-03-12","ACTUAL",{"date":106,"type":104},"2024-12-26",{"date":108,"type":93},"2028-03",{"name":5,"class":6},1]