[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100564314":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":29,"locations":35,"responsibleParty":51,"collaborators":18,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":18,"eligibilityCriteria":59,"healthyVolunteers":60,"sex":61,"minAge":62,"maxAge":63,"enrollmentInfo":64,"targetDuration":18,"studyType":67,"phases":68,"briefSummary":70,"conditions":71,"keywords":74,"overallStatus":78,"whyStopped":18,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"VA Office of Research and Development","FED",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Exercise","EXPERIMENTAL","Participants will complete 4 aerobic exercise training sessions per week for 12 weeks. The exercise program will begin at 15 minutes per session and duration will be gradually increased by 5 minutes each week until participants reach 30 minutes per session (with 5 min warm-up and cool-down). Exercise will be performed at a \"moderate\" intensity, which will be about 60-70% of your predicted maximal level. Participants will meet with study personnel once per week.",[13],"Behavioral: Exercise",{"label":15,"type":16,"description":17,"interventionNames":18},"Usual activity","NO_INTERVENTION","Participants will keep doing what they usually do for the 12-week intervention period. They will be asked not to change their usual physical activity levels during this period. They will meet with study personnel once per week",null,[20],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":18},"BEHAVIORAL","12 weeks of aerobic exercise, with 4 sessions per week.",[9],[25],{"name":26,"affiliation":27,"role":28},"Kristina T. Legget, PhD","Rocky Mountain Regional VA Medical Center, Aurora, CO","PRINCIPAL_INVESTIGATOR",[30],{"name":31,"role":32,"phone":33,"phoneExt":18,"email":34},"Kristina T Legget, PhD","CONTACT","(720) 724-5809","kristina.legget@va.gov",[36],{"facility":27,"status":18,"city":37,"state":38,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"Aurora","Colorado","80045-7211","United States","US",{"type":43,"coordinates":44},"Point",[45,46],-104.83192,39.72943,{"lat":46,"lon":45},[49,50],{"name":31,"role":32,"phone":33,"phoneExt":18,"email":34},{"name":26,"role":28,"phone":18,"phoneExt":18,"email":18},{"type":52,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR","100564314","exercise-effects-on-the-neurobiology-underlying-stress-related-eating-behaviors-in-veterans-100564314",false,"NCT06627569","Exercise Effects on the Neurobiology Underlying Stress-related Eating Behaviors in Veterans","Exercise Effects on the Neurobiology Underlying Stress-Related Eating Behaviors in Veterans","Inclusion Criteria:\n\n* Veterans 18-75 years old\n* BMI of 25 or greater\n* Physically inactive\n* Able to attend study visits in person in Aurora, CO\n\nExclusion Criteria:\n\n* Currently pregnant\n* History of bariatric surgery\n* Current eating disorder\n* Current treatment with appetite-altering medications (e.g., GLP-1 agonists)\n* Contraindication to MRI (weight \\> 500 lbs; claustrophobia; metal or electronic devices in the body)\n* Cardiovascular disease, chronic kidney disease, pulmonary disease, or diabetes\n* Unable to exercise due to cardiac, pulmonary, neurologic, or orthopedic reasons",true,"ALL","18 Years","75 Years",{"count":65,"type":66},132,"ESTIMATED","INTERVENTIONAL",[69],"NA","The purpose of this study is to learn more about how common lifestyle interventions, such as exercise, affect how our brains respond to performing thinking tasks and to viewing pictures of foods and various other objects. The investigators are also interested in how changes in hormones that might be different in men and women could affect how lifestyle interventions change these brain responses.",[72,73],"Overweight\u002FObesity","Stress",[75,76,73,77],"Overweight","Obesity","Eating","NOT_YET_RECRUITING","2026-06-11",{"date":81,"type":82},"2026-06-15","ACTUAL",{"date":84,"type":66},"2026-07-01",{"date":86,"type":66},"2030-08-30",{"name":5,"class":6},1]