[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100631308":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":18,"centralContacts":24,"locations":30,"responsibleParty":48,"collaborators":18,"id":50,"slug":51,"hasResults":52,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":56,"eligibilityCriteria":57,"healthyVolunteers":52,"sex":58,"minAge":59,"maxAge":18,"enrollmentInfo":60,"targetDuration":18,"studyType":63,"phases":64,"briefSummary":66,"conditions":67,"keywords":70,"overallStatus":74,"whyStopped":18,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"State University of Londrina","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Exercise intervention group","EXPERIMENTAL","The exercise group will be asked to complete 48 multicomponent, supervised exercise training sessions over 24 weeks, with a frequency of two sessions per week on non-consecutive days.",[13],"Other: Multimodal, supervised exercise training",{"label":15,"type":16,"description":17,"interventionNames":18},"Control group","NO_INTERVENTION","Patients in the waiting list control group received standard medical care without any exercise program or specific exercise recommendations. To maintain contact with the researchers and minimize drop-out, the waiting list control group received general health information through monthly online meetings.",null,[20],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":18},"Multimodal, supervised exercise training","The multicomponent exercise intervention included a 10-minute warm-up consisting of balance, coordination, and stretching exercises. The main component was resistance training targeting major upper and lower body muscle groups to improve muscle strength and mass. Six to eight exercises were performed using body weight, elastic bands, and dumbbells. Training progression was achieved by increasing load, repetitions, and\u002For sets, guided by the 0-10 Borg rating of perceived exertion when health status permitted. The aerobic component consisted of walking progressing to beginner-level running, using short running intervals (50-100 m) interspersed with walking until longer continuous distances were achieved. Heart rate was monitored throughout the aerobic session.",[9],[25],{"name":26,"role":27,"phone":28,"phoneExt":18,"email":29},"Rafael Deminice, PhD","CONTACT","+5543991916013","rdeminice@uel.br",[31],{"facility":5,"status":18,"city":32,"state":33,"zip":34,"country":35,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"Londrina","Paraná","86047-597","Brazil","BR",{"type":38,"coordinates":39},"Point",[40,41],-51.16278,-23.31028,{"lat":41,"lon":40},[44],{"name":45,"role":27,"phone":46,"phoneExt":18,"email":47},"Ivone Beraldo","+554333715953","cefepos@uel.br",{"type":49,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR","100631308","exercise-for-the-treatment-of-cancer-related-sarcopenia-100631308",false,"NCT07498985","Exercise for the Treatment of Cancer-Related Sarcopenia","Exercise for the Treatment of Cancer-Related Sarcopenia: a Randomised Controlled Trial.","HERA","Inclusion Criteria:\n\n* \\> 18 years old women with a confirmed diagnosis of breast or gynecological cancer.\n* Any level of sarcopenia (pre-sarcopenia, sarcopenia, or severe sarcopenia).\n* Patients must have completed their primary treatment regimen (surgery, chemotherapy, and\u002For radiotherapy) for at least 2 weeks and up to 2 years before enrolment.\n* have received the medical consent to be engaged in physical exercise programs.\n\nExclusion Criteria:\n\n* The presence of one or more comorbidities that could potentially interfere with attendance or test results (e.g., other cancers or acute or chronic renal failure);\n* Already in exercise programs comparable to the HERA program;\n* Evidence of severe cardiovascular disease as a result of an electrocardiogram.","FEMALE","18 Years",{"count":61,"type":62},78,"ESTIMATED","INTERVENTIONAL",[65],"NA","Our primary objective is to assess the effects of exercise on cancer-related sarcopenia and its hallmarks, including muscle strength, muscle mass, and physical performance. The secondary objectives are to examine exercise adherence and the effects of exercise on health-related quality of life (QoL), cancer-related fatigue, and sleep quality. Additionally, we will explore the effects of exercise on bone and fat mass as secondary outcomes.",[68,69],"Cancer","Sarcopenia",[71,72,73],"muscle loss","Frail","Resistance Training","NOT_YET_RECRUITING","2026-03-24",{"date":77,"type":78},"2026-03-27","ACTUAL",{"date":80,"type":62},"2026-04-01",{"date":82,"type":62},"2028-12",{"name":5,"class":6},1]