[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100624289":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":19,"centralContacts":30,"locations":19,"responsibleParty":36,"collaborators":19,"id":40,"slug":41,"hasResults":42,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":46,"eligibilityCriteria":47,"healthyVolunteers":42,"sex":48,"minAge":19,"maxAge":19,"enrollmentInfo":49,"targetDuration":19,"studyType":52,"phases":53,"briefSummary":55,"conditions":56,"keywords":19,"overallStatus":60,"whyStopped":19,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":19},{"fullName":5,"class":6},"São Paulo State University","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Intervention group","EXPERIMENTAL","Postmenopausal women undergoing a supervised combined exercise program (aerobic, resistance, and mind-body exercise).",[13,14],"Behavioral: Combined Exercise Program","Other: Usual Care Group",{"label":16,"type":17,"description":18,"interventionNames":19},"Control Group","NO_INTERVENTION","Postmenopausal women who will continue receiving usual care without participation in a structured exercise program during the study period.",null,[21,26],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":19},"BEHAVIORAL","Combined Exercise Program","Participants allocated to the intervention group will take part in a supervised combined exercise program, performed twice weekly for 12 months. Each session will last approximately 60 minutes and will include aerobic exercise, resistance training, and mind-body exercise.\n\nAerobic training will consist of walking or cycling at moderate intensity, monitored by heart rate. Resistance training will involve multi-joint exercises using body weight and elastic bands, with progressive overload. Mind-body exercise will be performed using restorative yoga techniques. Exercise sessions will be supervised by a trained physiotherapist.",[9],{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":19},"Usual Care Group","Participants allocated to the control group will continue with their usual care and daily activities, without participation in any structured or supervised exercise program during the study period.",[9],[31],{"name":32,"role":33,"phone":34,"phoneExt":19,"email":35},"Gabriela Ribeiro","CONTACT","55+18996921106","gabrielacarrion123@hotmail.com",{"type":37,"investigatorFullName":38,"investigatorTitle":39,"investigatorAffiliation":5,"oldNameTitle":19,"oldOrganization":19},"PRINCIPAL_INVESTIGATOR","Gabriela Carrion Caldeira Ribeiro","Masters","100624289","exercise-insulin-resistance-and-chronic-pain-in-postmenopausal-women-100624289",false,"NCT07407699","Exercise, Insulin Resistance, and Chronic Pain in Postmenopausal Women.","Isulin Resistance as a Mediator of Chronic Pain in Postmenopausal Women: Effects of a Combined Exercise Program on Metabolic and Inflammatory Mechanisms","EX-PAIN-MENO","Inclusion Criteria:\n\n* Postmenopausal women, defined as between 12 months and 5 years since the last menstrual period.\n* Not using hormone replacement therapy.\n* Not engaged in regular physical exercise (defined as more than once per week in the last months).\n* With or without insulin resistance.\n\nExclusion Criteria:\n\n* Diagnosis of neurological diseases (e.g., Parkinson's disease, multiple sclerosis, or stroke sequelae).\n* Severe psychiatric disorders.\n* Inflammatory autoimmune diseases (e.g., rheumatoid arthritis or systemic lupus erythematosus).\n* Active neoplasms.\n* Use of systemic corticosteroids or immunosuppressive drugs within the last three months.\n* Severe decompensated cardiovascular disease.\n* Any medical condition that contraindicates participation in physical exercise.","FEMALE",{"count":50,"type":51},50,"ESTIMATED","INTERVENTIONAL",[54],"NA","This study aims to investigate the effects of a combined exercise program on chronic pain in postmenopausal women, considering insulin resistance as a potential physiological mediator. The intervention will assess changes in pain intensity, metabolic and inflammatory biomarkers, psychosocial factors, and body composition. The findings may contribute to understanding the metabolic mechanisms underlying chronic pain in postmenopausal women and support exercise as a non-pharmacological therapeutic strategy.",[57,58,59],"Chronic Pain","Postmenopausal","Insulin Resistance","NOT_YET_RECRUITING","2026-02-05",{"date":63,"type":64},"2026-02-12","ACTUAL",{"date":66,"type":51},"2026-08",{"date":68,"type":51},"2027-07",{"name":5,"class":6}]