[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100610621":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":38,"centralContacts":42,"locations":48,"responsibleParty":77,"collaborators":29,"id":80,"slug":81,"hasResults":82,"nctId":83,"briefTitle":84,"officialTitle":85,"acronym":29,"eligibilityCriteria":86,"healthyVolunteers":87,"sex":88,"minAge":89,"maxAge":90,"enrollmentInfo":91,"targetDuration":29,"studyType":94,"phases":95,"briefSummary":97,"conditions":98,"keywords":103,"overallStatus":109,"whyStopped":29,"lastUpdateSubmitDate":110,"lastUpdatePostDateStruct":111,"startDateStruct":114,"completionDateStruct":116,"leadSponsor":118,"locationsCount":119},{"fullName":5,"class":6},"Hacettepe University","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Sedentary: Participants will remain seated for 7 h.","EXPERIMENTAL","The sedentary condition will take place in a seated position. During the seated condition, volunteers will be seated at a typical desk chair at an appropriate height with hip and knee angles of \\~90° and feet flat on the floor. The seating area will include a standard desk chair, a work desk, and the volunteers' personal laptops. Volunteers will be instructed prior to the visit to avoid behaviors such as fidgeting, excessive leg movements, and crossing their legs to minimize potential extraneous effects.",[13],"Other: Sedentary Behaviour Intervention",{"label":15,"type":10,"description":16,"interventionNames":17},"Breaking up sitting with aerobic exercise interruptions","The protocol that will interrupt sitting with AEI will involve cycle exercises performed at 50% of VO2max for 2 minutes. The W and rpm levels corresponding to 50% of VO2max will be determined using the values recorded during the determination of VO2max.",[18],"Other: Aerobic Exercise Intervention",{"label":20,"type":10,"description":21,"interventionNames":22},"Breaking up sitting with sprint exercise interruptions","The protocol that will interrupt sitting with SEI will involve cycle exercises performed at the maximum revolutions per minute achievable within 10 seconds. Immediately before each SEI, volunteers will increase their pedal cadence to the maximum speed they can achieve, after which a pedal load will be applied to the bicycle ergometer and a sprint will be performed against the applied load for 10 seconds. During each sprint, the pedal load will be applied at 0.065 kilograms per kilogram of lean body mass. Since it has been shown to lead to greater peak power output in overweight and obese groups, lean body mass will be used as a reference when determining pedal load, rather than total body mass.",[23],"Other: Sprint Exercise Intervention",[25,30,34],{"type":6,"name":26,"description":27,"armGroupLabels":28,"otherNames":29},"Aerobic Exercise Intervention","In the aerobic exercise condition, participants will perform 2 minutes of moderate-intensity continuous cycling.",[15],null,{"type":6,"name":31,"description":32,"armGroupLabels":33,"otherNames":29},"Sprint Exercise Intervention","In the sprint condition, participants will complete a 10-second all-out sprint, as determined during the preliminary test.",[20],{"type":6,"name":35,"description":36,"armGroupLabels":37,"otherNames":29},"Sedentary Behaviour Intervention","Participants will remain seated for a total duration of 7 hours. During this period, they will be instructed to minimize excessive movement and will only be permitted to rise from the chair for voiding purposes.",[9],[39],{"name":40,"affiliation":5,"role":41},"Şükran Nazan Koşar, Professor","PRINCIPAL_INVESTIGATOR",[43],{"name":44,"role":45,"phone":46,"phoneExt":29,"email":47},"Hikmet Sercan Toprakoğlu","CONTACT","+905369792652","sercantprkgl@gmail.com",[49],{"facility":50,"status":29,"city":51,"state":52,"zip":29,"country":53,"countryCode":29,"cosmosGeoPoint":54,"geoPoint":59,"contacts":60},"Hacettepe Sports Science Faculty, Hacettepe Beytepe Clinic","Ankara","Beytepe","Turkey (Türkiye)",{"type":55,"coordinates":56},"Point",[57,58],32.85427,39.91987,{"lat":58,"lon":57},[61,64,65,68,70,72,74,76],{"name":40,"role":45,"phone":62,"phoneExt":29,"email":63},"0538 861 29 24","nazankosar@gmail.com",{"name":44,"role":41,"phone":29,"phoneExt":29,"email":29},{"name":66,"role":67,"phone":29,"phoneExt":29,"email":29},"Seda Hanife Oğuz Baykal, Associate Professor","SUB_INVESTIGATOR",{"name":69,"role":67,"phone":29,"phoneExt":29,"email":29},"Muhammed Mustafa Atakan, Associate Professor",{"name":71,"role":67,"phone":29,"phoneExt":29,"email":29},"Yasemin Güzel, Doctoral faculty member",{"name":73,"role":67,"phone":29,"phoneExt":29,"email":29},"Yiğitcan Karanfil, Doctoral faculty member",{"name":75,"role":67,"phone":29,"phoneExt":29,"email":29},"İbrahim Türkel, Doctoral faculty member",{"name":40,"role":67,"phone":29,"phoneExt":29,"email":29},{"type":41,"investigatorFullName":78,"investigatorTitle":79,"investigatorAffiliation":5,"oldNameTitle":29,"oldOrganization":29},"Muhammed Mustafa Atakan","Associate Professor","100610621","exercise-intensity-and-postprandial-effects-of-breaking-sedentary-behavior-in-overweight-adults-100610621",false,"NCT07229963","Exercise Intensity and Postprandial Effects of Breaking Sedentary Behavior in Overweight Adults","Postprandial Cardiometabolic Effects of Interrupting Sedentary Behavior With Exercise of Varying Intensity in Healthy Overweight Adults","Inclusion Criteria\n\n* Being physically inactive (not doing at least 150 minutes\u002Fweek of structured exercise).\n* Having a physical activity level of \\\u003C5000 steps\u002Fday.\n* Having a BMI between 25 and 29.9 kg\u002Fm2.\n* Having a history of regular menstrual cycles for female participants.\n* Having medical examination approval.\n\nExclusion Criteria\n\n* Taking any acute or chronic medication or supplement that may affect metabolism.\n* Having an acute or chronic illness that limits exercise (musculoskeletal problems, cardiovascular disorders, respiratory problems, etc.).\n* Consuming tobacco products.\n* Meeting 3 or more of the metabolic syndrome criteria (waist circumference of 102 cm or more in men, 88 cm or more in women, triglyceride level of 150 mg\u002FdL or higher, HDL cholesterol level below 40 mg\u002FdL in men and 50 mg\u002FdL in women, blood pressure of 130\u002F85 mmHg or higher, fasting blood glucose level of 100 mg\u002FdL (5.6 mg\u002FL) or higher).",true,"ALL","35 Years","45 Years",{"count":92,"type":93},16,"ESTIMATED","INTERVENTIONAL",[96],"NA","The purpose of this study is twofold: (1) to determine whether breaking up prolonged sitting with aerobic or sprint cycling breaks reduces postprandial blood glucose, insulin, CRP, and blood pressure, which are established risk markers for cardiometabolic diseases; and (2) to assess substrate oxidation during this period in order to identify which exercise condition promotes the greatest increase in fat oxidation.",[99,100,101,102],"Cardiovascular Risk Markers","Substrate Oxidation","Postprandial Metabolism","Exercise Physiology",[104,105,106,107,108],"Exercise","Sedentary behavior","Cardiometabolic health","Postprandial metabolism","overweight","NOT_YET_RECRUITING","2025-11-13",{"date":112,"type":113},"2025-11-17","ACTUAL",{"date":115,"type":93},"2025-11-25",{"date":117,"type":93},"2026-06-15",{"name":5,"class":6},1]