[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100621150":3},{"organization":4,"armGroups":7,"interventions":26,"overallOfficials":22,"centralContacts":32,"locations":42,"responsibleParty":64,"collaborators":66,"id":72,"slug":73,"hasResults":74,"nctId":75,"briefTitle":76,"officialTitle":77,"acronym":22,"eligibilityCriteria":78,"healthyVolunteers":74,"sex":79,"minAge":80,"maxAge":22,"enrollmentInfo":81,"targetDuration":22,"studyType":84,"phases":85,"briefSummary":87,"conditions":88,"keywords":90,"overallStatus":44,"whyStopped":22,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":105},{"fullName":5,"class":6},"Golden Jubilee National Hospital","OTHER_GOV",[8,14,18,23],{"label":9,"type":10,"description":11,"interventionNames":12},"Exercise Intervention Group then Adherence package group during follow-up phase","EXPERIMENTAL","Initially randomised to the exercise intervention group. Following completion of the exercise intervention, then randomised to receive the adherence support package.",[13],"Other: Home-based, remotely delivered, supervised Exercise programme",{"label":15,"type":10,"description":16,"interventionNames":17},"Exercise Intervention Group then control group during follow-up phase","Initially randomised to the exercise intervention group. Following completion of the exercise intervention, then randomised to the control group during the follow-up phase, so not given the adherence support package.",[13],{"label":19,"type":20,"description":21,"interventionNames":22},"Control group, then the Adherence package group during the follow-up phase","NO_INTERVENTION","Initially randomised to the control group. Then randomised to receive the adherence support package in the follow-up phase",null,{"label":24,"type":20,"description":25,"interventionNames":22},"Control group, then also randomised to the control group in the follow-up phase","Initially randomised to the control group. Following completion of the exercise intervention, then randomised to be in the control group in follow-up phase, so not given the adherence support package.",[27],{"type":28,"name":29,"description":30,"armGroupLabels":31,"otherNames":22},"OTHER","Home-based, remotely delivered, supervised Exercise programme","A home-based remotely delivered supervised exercise programme",[9,15],[33,38],{"name":34,"role":35,"phone":36,"phoneExt":22,"email":37},"Jamie Ingram, MBChB","CONTACT","0044 141-951-5440","jamie.ingram2@nhs.scot",{"name":39,"role":35,"phone":40,"phoneExt":22,"email":41},"Colin Church, BSc, MBChB, PhD, FRCP","0044 141-951-5497","colinchurch@doctors.org.uk",[43],{"facility":5,"status":44,"city":45,"state":22,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"RECRUITING","Glasgow","G814DY","United Kingdom","UK",{"type":50,"coordinates":51},"Point",[52,53],-4.25763,55.86515,{"lat":53,"lon":52},[56,58,59,61],{"name":34,"role":35,"phone":57,"phoneExt":22,"email":37},"00441419515497",{"name":22,"role":35,"phone":22,"phoneExt":22,"email":37},{"name":34,"role":60,"phone":22,"phoneExt":22,"email":22},"SUB_INVESTIGATOR",{"name":62,"role":63,"phone":22,"phoneExt":22,"email":22},"Colin Church, BSc, MBChB, FRCP, PhD","PRINCIPAL_INVESTIGATOR",{"type":65,"investigatorFullName":22,"investigatorTitle":22,"investigatorAffiliation":22,"oldNameTitle":22,"oldOrganization":22},"SPONSOR",[67,70],{"name":68,"class":69},"Chiesi Farmaceutici S.p.A.","INDUSTRY",{"name":71,"class":28},"University of Glasgow","100621150","exercise-intervention-as-an-adjunct-to-medical-therapy-in-newly-diagnosed-patients-with-pulmonary-arterial-hypertension-100621150",false,"NCT07366879","Exercise Intervention as an Adjunct to Medical Therapy in Newly Diagnosed Patients With Pulmonary Arterial Hypertension","Randomised Controlled Trial of Exercise Intervention as an Adjunct to Medical Therapy in Newly Diagnosed Patients With Pulmonary Arterial Hypertension","Inclusion Criteria:\n\n* Aged 18-years-old and above\n* Diagnosed with pulmonary hypertension (group I and non-operable group IV) by right heart catheterisation showing:\n\n  * a baseline mean pulmonary artery pressure \\>20mmHg\n  * pulmonary vascular resistance \\>2 Wood Units\n  * pulmonary capillary wedge pressure \\\u003C15mmHg\n* Able to provide written informed consent\n\nExclusion Criteria:\n\n* Diagnosis with pulmonary hypertension of any other cause\n\n  * Group II (PH due to left heart disease)\n  * Group III (PH due to hypoxic lung disease)\n  * Operable group IV (PH due to chronic thromboembolic disease amenable to surgical treatment)\n  * Group V (unclear and\u002For multifactorial elements).\n* Planned treatment with a research trial medication during the study timeframe\n* Consenting clinician and\u002For patient concern regarding the patient's safety in performing a home-based exercise programme\n* Patients with syncopal episodes felt to be related to pulmonary hypertension at time of exercise intervention initiation.\n* Severe concurrent medical condition that would prevent participation in study procedures\n* Life expectancy \\\u003C3 months","ALL","18 Years",{"count":82,"type":83},40,"ESTIMATED","INTERVENTIONAL",[86],"NA","The goal of this clinical trial is to learn if an exercise programme started shortly after diagnosis improves the fitness and mental wellbeing of patients with pulmonary hypertenion over and above medication alone. It will also learn about whether extra support can help patients keep up with exercise in the long term. The main questions it aims to answer are:\n\n* Doe exercise improve how far patients can walk over six minutes\n* Does exercise improve quality of life scores\n* Does exercise improve mental health scores\n* Does extra support after an exercise programme help patients to continue exercising in the long term\n\nResearchers will compare the exercise programme to a control group (a group of similar patients who do not receive the exercise programme) to see the effect that exercise has.\n\nParticipants in the exercise programme group will:\n\n* Undergo an exercise programme for 12 weeks, starting around 3 months after their diagnosis\n* They will undertake the exercise programme at home, remotely supervised by the research team with regular contact\n* Visit the clinic at the end of the programme for checkups and tests\n* Keep a diary of their exercise and how they are feeling\n\nParticipants in the control group will:\n\n-Still undergo the exercise programme, but this will happen at a delayed time, starting around 6 months after diagnosis, to allow for a comparison between the two groups.\n\nFollowing completion of the exerise programme:\n\n* Half of participants will receive extra support to help them continue to exercise\n* The other half will not receive any additional support\n* All patients will be reviewed 1 year following the completion of their exercise programme to monitor their ongoing exercise levels.",[89],"Pulmonary Arterial Hypertension",[91,92,93,94,95],"pulmonary arterial hypertension","PAH","pulmonary hypertension","exercise training","exercise adherence","2026-05-12",{"date":98,"type":99},"2026-05-13","ACTUAL",{"date":101,"type":99},"2026-04-02",{"date":103,"type":83},"2028-01",{"name":5,"class":6},1]