[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100555648":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":8,"centralContacts":12,"locations":17,"responsibleParty":32,"collaborators":7,"id":34,"slug":35,"hasResults":36,"nctId":37,"briefTitle":38,"officialTitle":39,"acronym":40,"eligibilityCriteria":41,"healthyVolunteers":36,"sex":42,"minAge":43,"maxAge":7,"enrollmentInfo":44,"targetDuration":7,"studyType":47,"phases":7,"briefSummary":48,"conditions":49,"keywords":51,"overallStatus":19,"whyStopped":7,"lastUpdateSubmitDate":55,"lastUpdatePostDateStruct":56,"startDateStruct":59,"completionDateStruct":61,"leadSponsor":63,"locationsCount":64},{"fullName":5,"class":6},"University Medical Center Groningen","OTHER",null,[9],{"name":10,"affiliation":5,"role":11},"Thomas M Gorter, MD, PhD","PRINCIPAL_INVESTIGATOR",[13],{"name":10,"role":14,"phone":15,"phoneExt":7,"email":16},"CONTACT","+3150 361 6161","tm.gorter@umcg.nl",[18],{"facility":5,"status":19,"city":20,"state":7,"zip":21,"country":22,"countryCode":23,"cosmosGeoPoint":24,"geoPoint":29,"contacts":30},"RECRUITING","Groningen","9713GZ","Netherlands","NL",{"type":25,"coordinates":26},"Point",[27,28],6.56667,53.21917,{"lat":28,"lon":27},[31],{"name":10,"role":14,"phone":7,"phoneExt":7,"email":7},{"type":33,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR","100555648","exercise-magnetic-resonance-imaging-in-patients-with-obesity-associated-heart-failure-100555648",false,"NCT06514820","Exercise Magnetic Resonance Imaging in Patients With Obesity Associated Heart Failure","EXercise Magnetic Resonance Imaging in Patients With Obesity aSsociated Heart failURe With Preserved Ejection Fraction (EXPOSURE) Study","EXPOSURE","Inclusion Criteria:\n\n1. Signs and symptoms of HF according to the Europeans Society of Cardiology guideline.\n2. LV ejection fraction ≥40%.\n3. HFA-PEFF score ≥5 or HFA-PEFF score 2-4 in combination with positive stress test (Figure 1).\n4. \\>18 years of age\n5. In sinus rhythm\n6. Able to perform a bicycle exercise test\n7. Willing to sign informed consent\n\nExclusion Criteria:\n\n1. Body weight \\>140 kg\n2. Atrial fibrillation or other significant arrhythmia during the assessment\n3. Contraindications for CMR (e.g. claustrophobia, implanted cardiac devices)\n4. Myocardial infarction, percutaneous coronary intervention or coronary artery bypass graft \\\u003C3 months or untreated severe obstructive coronary artery stenosis\n5. More than moderate left-sided valve disease.\n6. Complex congenital heart disease.","ALL","18 Years",{"count":45,"type":46},50,"ESTIMATED","OBSERVATIONAL","To aim of the EXPOSURE study is to investigate the effects of epicardial fat on cardiac function, pericardial constraint and pulmonary artery vasodilatation using cardiac magnetic resonance (CMR) imaging at rest and during exercise stress testing in patients with HFpEF.",[50],"HFpEF - Heart Failure With Preserved Ejection Fraction",[52,53,54],"Epicardial fat","HFpEF","Exercise MRI","2024-07-16",{"date":57,"type":58},"2024-07-23","ACTUAL",{"date":60,"type":58},"2024-01-16",{"date":62,"type":46},"2025-12-31",{"name":5,"class":6},1]