[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100572600":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":24,"centralContacts":29,"locations":40,"responsibleParty":55,"collaborators":23,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":23,"eligibilityCriteria":64,"healthyVolunteers":60,"sex":65,"minAge":66,"maxAge":67,"enrollmentInfo":68,"targetDuration":23,"studyType":71,"phases":72,"briefSummary":74,"conditions":75,"keywords":78,"overallStatus":43,"whyStopped":23,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Randomization Order 1","EXPERIMENTAL","Participants will be randomized into one of the two groups indicating the order in which they will receive the exercise intervention.\n\nRandomization Order 1 will receive the exercise treatment on the first day of the first week of the study. The other three days without exercise will consist of standard dialysis sessions with study procedures.",[13],"Other: Intradialytic Cycling",{"label":15,"type":10,"description":16,"interventionNames":17},"Randomization Order 2","Participants will be randomized into one of the two groups indicating the order in which they will receive the exercise intervention.\n\nRandomization Order 2 will receive the exercise treatment on the first day of the fourth week of the study. The other three days without exercise will consist of standard dialysis sessions with study procedures.",[13],[19],{"type":6,"name":20,"description":21,"armGroupLabels":22,"otherNames":23},"Intradialytic Cycling","The impact of interdialytic exercise on cardio protection during HD has never been studied. This approach may enhance cardiovascular benefits and overall physical fitness, thereby contributing to better health outcomes in individuals undergoing HD.",[9,15],null,[25],{"name":26,"affiliation":27,"role":28},"Christopher McIntyre","London Health Sciences Centre Research Institute","PRINCIPAL_INVESTIGATOR",[30,36],{"name":31,"role":32,"phone":33,"phoneExt":34,"email":35},"Jarrin Penny, PhD, RN, CNeph (C)","CONTACT","519-685-8500","58765","jarrin.penny@lhsc.on.ca",{"name":37,"role":32,"phone":33,"phoneExt":38,"email":39},"Kathy Koyle","56214","kathleen.koyle@lhsc.on.ca",[41],{"facility":42,"status":43,"city":44,"state":45,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":23},"London Health Sciences Centre","RECRUITING","London","Ontario","N6A 5W9","Canada","CA",{"type":50,"coordinates":51},"Point",[52,53],-81.23304,42.98339,{"lat":53,"lon":52},{"type":28,"investigatorFullName":56,"investigatorTitle":57,"investigatorAffiliation":42,"oldNameTitle":23,"oldOrganization":23},"Chris McIntyre","Nephrologist, Professor of Medicine, Medical Biophysics and Paediatrics","100572600","exercise-preconditioning-to-protect-against-dialysis-induced-cardiac-injury-100572600",false,"NCT06735378","Exercise Preconditioning to Protect Against Dialysis-induced Cardiac Injury","Exercise Preconditioning to Protect Against Dialysis-induced Cardiac Injury in Hemodialysis Patients: a Randomized Controlled Trial","Inclusion Criteria:\n\n* must be on chronic hemodialysis for at least 3 months\n* age 18 years or older\n* willing and able to provide informed consent\n* assessed to be safe and able to exercise by unit HD Nephrologist\n\nExclusion Criteria:\n\n* regular vigorous exercise outside of hemodialysis\n* over 79 years of age\n* intradialytic exercise \\\u003C 3 months\n* poor echogenicity\n* acute coronary syndrome in the past 3 months\n* unstable arrhythmia\u002Fangina\n* shortness of breath at rest or with minimal activity\n* symptomatic hypoglycemia (\\>2x\u002Fweek in the week prior to enrolment)","ALL","18 Years","79 Years",{"count":69,"type":70},30,"ESTIMATED","INTERVENTIONAL",[73],"NA","The goal of this study is to determine what happens to the heart muscle contraction when people cycle before their hemodialysis treatment. Will pre-dialysis exercise protect the heart from a decrease in pumping of the heart muscle (called stunning) that can happen during hemodialysis. We will study whether pre-dialysis exercise decreases heart stunning, decreases the number and severity of symptoms commonly associated with hemodialysis, and other outcomes",[76,77],"Hemodialysis","Cardioprotection",[77,79,76],"Preconditioning Exercise","2025-01-20",{"date":82,"type":83},"2025-01-22","ACTUAL",{"date":80,"type":83},{"date":86,"type":70},"2025-12-31",{"name":5,"class":6},1]