[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100464420":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":33,"locations":39,"responsibleParty":60,"collaborators":62,"id":68,"slug":69,"hasResults":70,"nctId":71,"briefTitle":72,"officialTitle":73,"acronym":24,"eligibilityCriteria":74,"healthyVolunteers":70,"sex":75,"minAge":76,"maxAge":24,"enrollmentInfo":77,"targetDuration":24,"studyType":80,"phases":81,"briefSummary":83,"conditions":84,"keywords":88,"overallStatus":42,"whyStopped":24,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},{"fullName":5,"class":6},"Dana-Farber Cancer Institute","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Aerobic and resistance exercise","EXPERIMENTAL","Virtually supervised 16-week aerobic and resistance exercise performed at home via Zoom.\n\nThe exercises will be performed three times per week for 16 weeks, and virtually supervised by a professional exercise trainer.",[13],"Other: Aerobic and resistance exercise",{"label":15,"type":16,"description":17,"interventionNames":18},"Usual care","ACTIVE_COMPARATOR","Maintenance of baseline exercise levels for 16 weeks with an offer to perform the same exercise program after 16 weeks.",[19],"Other: Usual Care",[21,25],{"type":6,"name":9,"description":22,"armGroupLabels":23,"otherNames":24},"Perform exercise at home with virtual supervision, including aerobic exercise (e.g.,cycling), which can improve cardiovascular (heart) and lung function, and resistance exercise (e.g., dumbbell lifting and using resistance band. The exercises will be performed three times per week for 16 weeks, and virtually supervised by a professional exercise trainer",[9],null,{"type":6,"name":26,"description":27,"armGroupLabels":28,"otherNames":24},"Usual Care","Maintenance of baseline exercise levels for 16 weeks with an offer to perform the same exercise (aerobic and resistance exercise) program after 16 weeks.",[15],[30],{"name":31,"affiliation":5,"role":32},"Christina C Dieli-Conwright, PhD, MPH","PRINCIPAL_INVESTIGATOR",[34],{"name":35,"role":36,"phone":37,"phoneExt":24,"email":38},"Christina Dieli-Conwright, PhD, MPH","CONTACT","617-632-3800","ChristinaM_Dieli-Conwright@dfci.harvard.edu",[40],{"facility":41,"status":42,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"Dana Farber Cancer Institute","RECRUITING","Boston","Massachusetts","02215","United States","US",{"type":49,"coordinates":50},"Point",[51,52],-71.05977,42.35843,{"lat":52,"lon":51},[55,56,58],{"name":35,"role":36,"phone":37,"phoneExt":24,"email":38},{"name":57,"role":36,"phone":24,"phoneExt":24,"email":24},"PhD, MPH",{"name":59,"role":32,"phone":24,"phoneExt":24,"email":24},"Christina Dieli-Conwright, PhD",{"type":32,"investigatorFullName":59,"investigatorTitle":61,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"Principal Investigator",[63,66],{"name":64,"class":65},"Pfizer","INDUSTRY",{"name":67,"class":6},"Prostate Cancer Foundation","100464420","exercise-to-enhance-cardiovascular-health-among-black-prostate-cancer-patients-with-androgen-deprivation-therapy-100464420",false,"NCT05327465","Exercise to Enhance Cardiovascular Health Among Black Prostate Cancer Patients With Androgen Deprivation Therapy","Exercise to Enhance Cardiovascular Health Among Black Prostate Cancer Patients With Androgen Deprivation Therapy: POWER Trial","Inclusion Criteria:\n\n* Patients must meet all criteria to be eligible, including travel to Dana-Farber Cancer Institute (DFCI) to collect research data to address the study question.\n* Over 18 years old; children under the age of 18 will be excluded due to the rarity of the disease\n* Histologically diagnosed of localized or metastatic prostate cancer\n* Have been receiving androgen deprivation therapy (ADT) (i.e., luteinizing hormone-releasing hormone \\[LHRH\\] agonist\u002Fantagonist and\u002For androgen receptor \\[AR\\] agonist\u002Fantagonist) for at least one month with a plan to continue ADT for at least 4 months at the time of recruitment\n* Self-identify as Black\n* Medically cleared to participate in exercise by their referred physician or a certified clinical exercise physiologist\n* Are without medical conditions that could exacerbate with exercise, such as bone disease (excluding bone metastases) at imminent risk of fracture or uncontrolled cardiopulmonary or metabolic diseases\n* Speak English and\u002For Spanish\n* Currently participate in less than or equal to 60 minutes of moderate or vigorous structured exercise\u002Fweek\n* Willing to travel to DFCI for necessary data collection\n* Ability to communicate and complete written forms in English and\u002For Spanish\n\nExclusion Criteria:\n\n* Are not receiving ADT (i.e., LHRH agonist\u002Fantagonist and\u002For AR agonist\u002Fantagonist)\n* Pre-existing medical conditions such as uncontrolled cardiopulmonary disease, or metabolic diseases that could exacerbate with exercise\n* Are not English or Spanish speaking\n* Patients with secondary diagnosis (with the exception of basal cell carcinoma)\n* Participate in more than 60 minutes of moderate or vigorous structured exercise\u002Fweek\n* Unable to travel to DFCI for necessary data collection\n* May not be able to comply with the safety monitoring requirements of the study in the opinion of the investigator.","MALE","18 Years",{"count":78,"type":79},62,"ESTIMATED","INTERVENTIONAL",[82],"NA","The purpose of this research is to determine whether a 16-week culturally tailored, technology-based, aerobic and resistance exercise intervention improves cardiovascular risk factors in Black men diagnosed with prostate cancer and are undergoing androgen deprivation therapy (ADT), and whether it will also improve physical fitness and function, body composition, and outcomes such as quality of life, cancer symptoms, and self-esteem.\n\nParticipants in this study will be randomly assigned to one of two groups: 1) Aerobic and resistance exercise, or 2) Usual care.",[85,86,87],"Androgen Deprivation Therapy","Prostate Cancer","Prostate Cancer Metastatic",[89,90,87,91],"Androgen deprivation therapy","Localized Prostate Cancer","Exercise","2026-01-20",{"date":94,"type":95},"2026-01-22","ACTUAL",{"date":97,"type":95},"2022-08-11",{"date":99,"type":79},"2026-12-31",{"name":5,"class":6},1]