[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100625473":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":26,"responsibleParty":37,"collaborators":26,"id":41,"slug":42,"hasResults":43,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":26,"eligibilityCriteria":47,"healthyVolunteers":43,"sex":48,"minAge":49,"maxAge":26,"enrollmentInfo":50,"targetDuration":26,"studyType":53,"phases":54,"briefSummary":56,"conditions":57,"keywords":59,"overallStatus":64,"whyStopped":26,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":26},{"fullName":5,"class":6},"European University of Madrid","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Exergame-Based Rehabilitation","EXPERIMENTAL","Participants assigned to the experimental group will complete a semi-autonomous upper-limb rehabilitation program based on exergames. The intervention includes task-oriented, progressive training targeting upper-limb motor function, visuomotor coordination, and cognitive engagement (e.g., attention, decision-making). Difficulty is adjusted individually based on performance, and sessions are remotely monitored by clinicians.",[13],"Behavioral: Exergame-Based Upper-Limb Training",{"label":15,"type":16,"description":17,"interventionNames":18},"Conventional Home-Based Rehabilitation","ACTIVE_COMPARATOR","Participants in the control group will receive an individualized home-based upper-limb rehabilitation program delivered through conventional therapeutic exercises equivalent in duration and content focus (motor control, coordination, precision). The intervention is prescribed by a therapist and supervised periodically, without digital gaming components.",[19],"Behavioral: Conventional Individual Rehabilitation",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"BEHAVIORAL","Exergame-Based Upper-Limb Training","Participants will perform an individualized exergame-based rehabilitation protocol designed to provide intensive, repetitive, and task-specific upper-limb training. The program integrates multisensory feedback, progressive difficulty adjustment, and monitoring of digital performance indicators (e.g., adherence, task completion, motor accuracy).\n\nDosage: Participants will complete the intervention 5 times per week over an 8-week period. Each session will last approximately 30-40 minutes.\n\nOutcome assessments at baseline(V0), week 8 (V1), and week 16 (V2) to examine maintenance of benefits.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Conventional Individual Rehabilitation","Participants assigned to the control group will receive an individualized conventional upper-limb rehabilitation program delivered through standard therapeutic exercises equivalent in therapeutic goals to the exergame protocol. Exercises target upper-limb motor function, coordination, and performance of functional tasks. This intervention does not include exergames, digital monitoring, or gamified feedback.\n\nDosage: Participants will complete the intervention 5 times per week over an 8-week period. Each session will last approximately 30-40 minutes.\n\nOutcome assessments at baseline(V0), week 8 (V1), and week 16 (V2) to examine maintenance of benefits.",[15],[32],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Marina Castel-Sánchez, PhD","CONTACT","+34679448994","marina.castel@universidadeuropea.es",{"type":38,"investigatorFullName":39,"investigatorTitle":40,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"SPONSOR_INVESTIGATOR","Marina Castel Sánchez","Associate Professor","100625473","exergame-based-upper-limb-rehabilitation-in-adults-with-chronic-stroke-100625473",false,"NCT07423091","Exergame-Based Upper-Limb Rehabilitation in Adults With Chronic Stroke","A Randomized Controlled Trial Assessing the Efficacy, Feasibility, and Usability of an Exergame-Based Semi-Autonomous Upper-Limb Rehabilitation Program in Individuals With Chronic Stroke","Inclusion Criteria:\n\n* Adults aged 18 years or older.\n* Confirmed diagnosis of chronic stroke with more than 6 months of evolution.\n* Ability to maintain independent sitting and standing (with or without assistive devices).\n* Upper-limb functional capacity ranging from limited to moderate, defined as an ARAT score between 11 and 54 points.\n* Ability to understand and follow simple instructions (Mini-Mental State Examination ≥ 23).\n* Ability to provide informed consent personally or through a legal representative.\n\nExclusion Criteria:\n\n* Acute illness, musculoskeletal pathology, or pain that interferes with the performance of rehabilitation exercises.\n* Uncompensated sensory deficits, including significant visual or hearing impairments.\n* Disruptive behavior or neuropsychiatric conditions that may limit participation.\n* Active epilepsy or any medical contraindication to physical exercise.\n* Botulinum toxin treatment affecting the upper limb within the previous 6 months.","ALL","18 Years",{"count":51,"type":52},32,"ESTIMATED","INTERVENTIONAL",[55],"NA","This study is a randomized controlled trial designed to evaluate the effectiveness of a semi-autonomous upper-limb rehabilitation program based on exergames in adults with chronic stroke. Participants will be randomly assigned (1:1) to either an exergame-based intervention or an individually delivered conventional home-based therapy program. The primary outcome is upper-limb functionality as measured by the Action Research Arm Test (ARAT). Secondary outcomes include upper-limb motor function and quality of life. The study also examines adherence, usability, and the feasibility of remote monitoring for long-term implementation.",[58],"Chronic Stroke",[58,60,61,62,63],"Upper Limb Rehabilitation","Exergames","Serious Games","Telerehabilitation","NOT_YET_RECRUITING","2026-02-18",{"date":67,"type":68},"2026-02-20","ACTUAL",{"date":70,"type":52},"2026-04",{"date":72,"type":52},"2026-12",{"name":39,"class":6}]