[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100636744":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":11,"centralContacts":29,"locations":35,"responsibleParty":51,"collaborators":11,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":11,"eligibilityCriteria":59,"healthyVolunteers":55,"sex":60,"minAge":61,"maxAge":11,"enrollmentInfo":62,"targetDuration":11,"studyType":65,"phases":66,"briefSummary":68,"conditions":69,"keywords":11,"overallStatus":38,"whyStopped":11,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":80},{"fullName":5,"class":6},"Zagazig University","OTHER_GOV",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Exosomes","ACTIVE_COMPARATOR",null,[13],"Other: Intralesional exosomes",{"label":15,"type":16,"description":11,"interventionNames":17},"Saline","PLACEBO_COMPARATOR",[18],"Other: Intralesional Saline",[20,25],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":11},"OTHER","Intralesional exosomes","exosomes are injected within the substance of the scar.",[9],{"type":21,"name":26,"description":27,"armGroupLabels":28,"otherNames":11},"Intralesional Saline","all patients will receive both, exosomes and saline, each injected into one scar.",[15],[30],{"name":31,"role":32,"phone":33,"phoneExt":11,"email":34},"mona Elradi","CONTACT","+201067070550","monaelradi@medicine.zu.edu.eg",[36],{"facility":37,"status":38,"city":39,"state":39,"zip":40,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"Zagazig University Hospitals","RECRUITING","Zagazig","44519","Egypt","EG",{"type":44,"coordinates":45},"Point",[46,47],31.502,30.58768,{"lat":47,"lon":46},[50],{"name":31,"role":32,"phone":33,"phoneExt":11,"email":34},{"type":52,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100636744","exososmes-in-atrophic-scars-management-100636744",false,"NCT07569666","Exososmes in Atrophic Scars Management","Evaluation of Intralesional Exosomes Versus Intralesional Saline in The Treatment of Atrophic Scars: A Randomized Controlled Trial","Inclusion Criteria:\n\nAge \\>18 years\n\n* Either gender\n* Scars of any duration\n* Multiple scars at one side or both sides of the face.\n* Patients are willing to sign written informed consent statements before beginning treatment.\n\nExclusion Criteria:\n\n* Pregnant females.\n* Patients with one scar.\n* Hypersensitivity to any of the used treatments.\n* Patient with infection at the site of the scar.\n* Patients with unrealistic expectations.\n* Patient refusing to sign on the consent.","ALL","18 Years",{"count":63,"type":64},12,"ESTIMATED","INTERVENTIONAL",[67],"NA","Lay Summary (Simple Explanation)\n\nAtrophic scars are depressed scars that form when the skin does not heal properly, commonly seen after acne or injuries. These scars can affect appearance and confidence, and current treatments may not always give satisfactory results.\n\nThis study aims to evaluate a new treatment using exosomes, which are tiny particles naturally released by cells that help in skin repair and regeneration. Researchers will compare the effect of injecting exosomes directly into scars versus injecting a simple saltwater solution (saline), which serves as a control.\n\nParticipants will be randomly assigned to receive either exosome injections or saline injections. Neither the patient nor the evaluator may know which treatment is given, to ensure fair comparison.\n\nThe goal is to determine whether exosomes can safely and effectively improve the appearance and texture of atrophic scars.",[70],"Atrophic Scar","2026-05-01",{"date":73,"type":74},"2026-05-06","ACTUAL",{"date":76,"type":74},"2025-06-15",{"date":78,"type":64},"2027-02",{"name":5,"class":6},1]