[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100629594":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":35,"centralContacts":62,"locations":68,"responsibleParty":85,"collaborators":87,"id":94,"slug":95,"hasResults":96,"nctId":97,"briefTitle":98,"officialTitle":99,"acronym":100,"eligibilityCriteria":101,"healthyVolunteers":102,"sex":103,"minAge":104,"maxAge":105,"enrollmentInfo":106,"targetDuration":10,"studyType":109,"phases":10,"briefSummary":110,"conditions":111,"keywords":124,"overallStatus":71,"whyStopped":10,"lastUpdateSubmitDate":133,"lastUpdatePostDateStruct":134,"startDateStruct":137,"completionDateStruct":139,"leadSponsor":141,"locationsCount":142},{"fullName":5,"class":6},"Danderyd Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"SCAPIS Stockholm reexamination substudy",null,"In SCAPIS (2014 -2018) 30.000 randomly selected adults between the ages of 50 - 64 were included. SCAPIS Reexamination is the re-assessment study of half of the original study cohort. In Stockholm (Danderyd University Hospital site) that corresponds to 2500 adults that are now between 6-10 years older than in the first SCAPIS study. The present study is a prospective, observational substudy of a convenient sample from the SCAPIS reexamination in Stockholm.",[13,14,15,16],"Diagnostic Test: Coronary computer tomography (CCTA)","Diagnostic Test: Echocardiograhy and aortic ultrasound","Diagnostic Test: Liver elastography","Diagnostic Test: Arterial stiffness",[18,23,27,31],{"type":19,"name":20,"description":21,"armGroupLabels":22,"otherNames":10},"DIAGNOSTIC_TEST","Coronary computer tomography (CCTA)","Siemens Naeotom Alpha Photon Counting CT scanner",[9],{"type":19,"name":24,"description":25,"armGroupLabels":26,"otherNames":10},"Echocardiograhy and aortic ultrasound","Echocardiograhy and aortic ultrasound using General Electric Vivid E95",[9],{"type":19,"name":28,"description":29,"armGroupLabels":30,"otherNames":10},"Liver elastography","Liver elastography using Fibroscan ultrasound method.",[9],{"type":19,"name":32,"description":33,"armGroupLabels":34,"otherNames":10},"Arterial stiffness","Arterial stiffness using Arteriograph, Tensiomed, Hungary and Photoplethysmography and ECG by ADInstrument",[9],[36,40,42,44,46,48,50,52,54,56,58,60],{"name":37,"affiliation":38,"role":39},"Rebecka Hultgren","Karolinska Institutet","PRINCIPAL_INVESTIGATOR",{"name":41,"affiliation":38,"role":39},"Karin Leander",{"name":43,"affiliation":38,"role":39},"Paolo Parini",{"name":45,"affiliation":38,"role":39},"Daniel Andersson",{"name":47,"affiliation":38,"role":39},"Matteo Pedrelli",{"name":49,"affiliation":38,"role":39},"Apostolos Bossios",{"name":51,"affiliation":38,"role":39},"Georgios Belibasakis",{"name":53,"affiliation":38,"role":39},"Tomas Jernberg",{"name":55,"affiliation":38,"role":39},"Hannes Hagström",{"name":57,"affiliation":38,"role":39},"Magnus Bäck",{"name":59,"affiliation":38,"role":39},"Bahira Shahim",{"name":61,"affiliation":38,"role":39},"Zhichao Zhou",[63],{"name":64,"role":65,"phone":66,"phoneExt":10,"email":67},"Jonas Spaak, MD, PhD, Professor","CONTACT","+4681235500","jonas.spaak@ki.se",[69],{"facility":70,"status":71,"city":72,"state":10,"zip":73,"country":74,"countryCode":75,"cosmosGeoPoint":76,"geoPoint":81,"contacts":82},"Cardiovascular Research Lab, Dept Cardiology, Danderyd University Hospital","RECRUITING","Stockholm","18288","Sweden","SE",{"type":77,"coordinates":78},"Point",[79,80],18.06871,59.32938,{"lat":80,"lon":79},[83],{"name":64,"role":65,"phone":84,"phoneExt":10,"email":67},"+46812355000",{"type":86,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[88,91,92],{"name":89,"class":90},"Region Stockholm","OTHER_GOV",{"name":38,"class":6},{"name":93,"class":6},"Göteborg University","100629594","expanded-studies-on-the-scapis-stockholm-reexamination-cohort-100629594",false,"NCT07476703","Expanded Studies on the SCAPIS Stockholm Reexamination Cohort","Expanded Studies of Risk Factors for Pulmonary-, Liver-, and Cardiovascular Disease in the SCAPIS 2 Stockholm Reexamination","SCAPIS-ReEx","Inclusion Criteria: Subjects already included in the main \u002F general SCAPIS reexamination study in Stockholm.\n\nExclusion Criteria: Inability to provide consent.",true,"ALL","56 Years","74 Years",{"count":107,"type":108},1400,"ESTIMATED","OBSERVATIONAL","The Swedish CArdioPulmonary bioImage Study (SCAPIS) is a unique, large-scale national research initiative involving 30,000 randomly selected individuals aged 50-64, recruited between 2014 and 2018. The study is a collaborative effort among six university hospitals across Sweden. A follow-up study, SCAPIS 2, is conducted for half of the original participants. In Stockholm, 2,500 individuals will be re-examined at Danderyd University Hospital and Karolinska Institutet.\n\nSCAPIS 2 includes a core set of examinations involving blood sampling, questionnaires, and imaging. In addition to these, complementary local investigations are conducted to enable more detailed research questions. This protocol describes the additional studies conducted in the Stockholm cohort. All complementary assessments aim to identify risk factors for current and future lung, liver, and cardiovascular diseases.:\n\nEXTENDED SAMPLING: Saliva and Blood Samples with Blood Cell Isolation. EXTENDED QUESTIONNAIRES: Dyspnea, Sleep, Respiratory Infections, and Dental Health.\n\nEXTENDED IMAGING AND PHYSIOLOGICAL MEASUREMENTS Cardiac Ultrasound and Abdominal Aortic Measurements. Liver Elastography. Vascular Stiffness by cuff-based pulse wave analysis and Photoplethysmography (PPG). Valvular and Vascular Calcification by CT imaging.",[112,113,114,115,116,117,118,119,120,121,122,123],"Coronary Artery Disease","Arterial Stiffness, Blood Pressure","AORTIC VALVE DISEASES","Mitral Valve Stenosis and\u002For Insufficiency","Heart Failure","Pulmonary Disease, Chronic Obstructive (COPD)","Steatohepatitis","Inflammation Biomarkers","Lipid Profile","Oral Microbiota","MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease","Metabolic Associated-dysfunction Steatohepatitis (MASH)",[125,126,127,128,129,130,131,132],"coronary artery disease","arterial stiffness","MASLD","COPD","inflammation","dyslipidemia","aortic aneurysm","oral microbiota","2026-03-12",{"date":135,"type":136},"2026-03-17","ACTUAL",{"date":138,"type":136},"2024-04-08",{"date":140,"type":108},"2026-08-30",{"name":5,"class":6},1]