[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100636761":3},{"organization":4,"armGroups":7,"interventions":15,"overallOfficials":11,"centralContacts":25,"locations":32,"responsibleParty":49,"collaborators":11,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":55,"acronym":56,"eligibilityCriteria":57,"healthyVolunteers":53,"sex":58,"minAge":59,"maxAge":11,"enrollmentInfo":60,"targetDuration":11,"studyType":63,"phases":64,"briefSummary":66,"conditions":67,"keywords":69,"overallStatus":75,"whyStopped":11,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"University Hospital, Montpellier","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Experimental arm","EXPERIMENTAL",null,[13,14],"Radiation: 18F-FDG PET imaging","Other: Neuropsychological Assessment",[16,21],{"type":17,"name":18,"description":19,"armGroupLabels":20,"otherNames":11},"RADIATION","18F-FDG PET imaging","For the 18F-FDG (fluorodeoxyglucose labelled with fluorine-18) PET scan, a dynamic protocol with the radiopharmaceutical injected directly under the scanner.\n\nThe dose injected will be the same as that used in routine clinical practice, i.e. calculated based on the patient's weight.\n\nThe patient must fast for 6 hours prior to the examination. The total duration of the dynamic PET scan is estimated at approximately 1 hour 30 minutes.",[9],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":11},"Neuropsychological Assessment","For the neuropsychological assessment, a series of standardised tests, validated for the assessment of cognitive functions, will be administered. This assessment will be carried out by neuropsychologists trained in the use of these tests and who administer them as part of their routine practice, or by a trained physiatrist specialising in disorders of the central nervous system. The neuropsychological assessment is expected to take 2 to 3 hours per visit for the patient.",[9],[26],{"name":27,"role":28,"phone":29,"phoneExt":30,"email":31},"Lucas RIBEIRO, Dr","CONTACT","0467337432","+33","l-ribeiro@chu-montpellier.fr",[33],{"facility":34,"status":11,"city":35,"state":36,"zip":37,"country":36,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"CHU de Montpellier","Montpellier","France","34295","FR",{"type":40,"coordinates":41},"Point",[42,43],3.87635,43.61093,{"lat":43,"lon":42},[46,47],{"name":27,"role":28,"phone":29,"phoneExt":30,"email":31},{"name":27,"role":48,"phone":11,"phoneExt":11,"email":11},"PRINCIPAL_INVESTIGATOR",{"type":50,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100636761","exploratory-study-of-cerebral-perfusion-and-metabolic-alterations-and-neurocognitive-disorders-in-patients-with-unruptured-arteriovenous-malformations-before-and-after-surgical-treatment-100636761",false,"NCT07569887","Exploratory Study of Cerebral Perfusion and Metabolic Alterations and Neurocognitive Disorders in Patients With Unruptured Arteriovenous Malformations Before and After Surgical Treatment","APEMMAV-NR","Inclusion Criteria:\n\n* Adults aged 18 and older\n* Admitted for an unruptured arteriovenous malformation with a decision to proceed with surgery\n\nExclusion Criteria:\n\n* Patients who refuse surgical treatment for arteriovenous malformation\n* Contraindications to 18F-FDG PET (uncontrolled diabete)\n* Patients' inability to lie still for 40 minutes\n* Patients with a confirmed diagnosis of neurodegenerative or psychiatric disorders\n* Pregnant or breastfeeding women (Article L.1121-5 of the French Public Health Code)\n* Persons deprived of their liberty by judicial or administrative decision (Article L.1121-6 of the French Public Health Code)\n* Persons who are subject to legal protection measures or who are unable to express their consent (guardianship, curatorship, judicial protection; Article L.1121-8 of the French Public Health Code)\n* Not affiliated with a social security scheme or beneficiary of such a scheme (Article L.1121-8-1 of the French Public Health Code)\n* Persons participating in another study that includes an ongoing exclusion period (Article L.1121-12 of the French Public Health Code)\n* Failure to obtain written informed consent","ALL","18 Years",{"count":61,"type":62},10,"ESTIMATED","INTERVENTIONAL",[65],"NA","The goal of the clinical trial is to describe perfusion and metabolic alterations in different brain regions before and six months after surgical treatment of arteriovenous malformations in adult patients with unruptured arteriovenous malformations.",[68],"Unruptured Brain Arteriovenous Malformation",[70,71,72,73,74],"Arteriovenous malformation","Perfusion disorders","Metabolism","Positon Emission Tomography","Neuropathology","NOT_YET_RECRUITING","2026-05-04",{"date":78,"type":79},"2026-05-06","ACTUAL",{"date":81,"type":62},"2026-05",{"date":83,"type":62},"2028-11",{"name":5,"class":6},1]