[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100553039":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":7,"centralContacts":8,"locations":7,"responsibleParty":16,"collaborators":7,"id":18,"slug":19,"hasResults":20,"nctId":21,"briefTitle":22,"officialTitle":23,"acronym":24,"eligibilityCriteria":25,"healthyVolunteers":20,"sex":26,"minAge":27,"maxAge":28,"enrollmentInfo":29,"targetDuration":7,"studyType":32,"phases":7,"briefSummary":33,"conditions":34,"keywords":39,"overallStatus":41,"whyStopped":7,"lastUpdateSubmitDate":42,"lastUpdatePostDateStruct":43,"startDateStruct":46,"completionDateStruct":48,"leadSponsor":50,"locationsCount":7},{"fullName":5,"class":6},"The Christie NHS Foundation Trust","OTHER",null,[9,14],{"name":10,"role":11,"phone":12,"phoneExt":7,"email":13},"Shermaine Pan, Dr","CONTACT","01614463000","the-christie.sponsoredresearch@nhs.net",{"name":15,"role":11,"phone":12,"phoneExt":7,"email":13},"Christie NHS",{"type":17,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR","100553039","exploratory-study-of-ebv-dna-titre-clearance-whilst-on-proton-beam-therapy-100553039",false,"NCT06480903","Exploratory Study of EBV DNA Titre Clearance Whilst on Proton Beam Therapy","Exploratory Study of Plasma Epstein Barr Virus (EBV) DNA Clearance During Proton Beam Therapy (PBT) for Nasopharyngeal Carcinoma (NPC)","ClearED","Inclusion Criteria:\n\n* Children and young adults (8-30 years old)\n* Pathologically confirmed EBV-positive nasopharyngeal carcinoma\n* Stage I-IVA (AJCC 8th Edition)\n* Planned to commence curative-intent radiation therapy\n\nExclusion Criteria:\n\n* Recurrent NPC\n* Concurrent or previously treated EBV-associated malignancy\n* Prior radiation therapy\n* Contraindications to MRI\n* General anaesthetic requirement for MRI","ALL","8 Years","30 Years",{"count":30,"type":31},10,"ESTIMATED","OBSERVATIONAL","How does plasma Epstein-Barr Virus (EBV) DNA level change during definitive radiation therapy for nasopharyngeal carcinoma (NPC) in the teenage and young adult cohort and does it correlate with outcomes?",[35,36,37,38],"Nasopharyngeal Carcinoma","Head and Neck Cancer","Nasopharyngeal Cancer","Epstein-Barr Virus",[40],"Nasopharyngeal, cancer, proton beam, epstein-barr virus","NOT_YET_RECRUITING","2024-06-25",{"date":44,"type":45},"2024-06-28","ACTUAL",{"date":47,"type":31},"2024-08-30",{"date":49,"type":31},"2026-08-30",{"name":5,"class":6}]