[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100629695":3},{"organization":4,"armGroups":7,"interventions":16,"overallOfficials":38,"centralContacts":43,"locations":48,"responsibleParty":64,"collaborators":10,"id":66,"slug":67,"hasResults":68,"nctId":69,"briefTitle":70,"officialTitle":71,"acronym":72,"eligibilityCriteria":73,"healthyVolunteers":68,"sex":74,"minAge":75,"maxAge":10,"enrollmentInfo":76,"targetDuration":10,"studyType":79,"phases":10,"briefSummary":80,"conditions":81,"keywords":84,"overallStatus":50,"whyStopped":10,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":98},{"fullName":5,"class":6},"Thomas Jefferson University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"EXIST Cohort",null,"Women over the age of 18 with an ECOG score \\\u003C 2 with a biopsy proven invasive breast cancer or ductal carcinoma in situ of the breast who are candidates for definitive breast cancer surgery",[13,14,15],"Other: Survey Assessments","Other: Diet Recall","Other: Blood Biomarker Collection",[17,26,32],{"type":6,"name":18,"description":19,"armGroupLabels":20,"otherNames":21},"Survey Assessments","The CMS Social Determinant of Health (SDOH) Survey refers to CMS's standardized screening tool used to identify patient needs related to housing, food, transportation, utilities, and safety. It helps providers address non-medical barriers to care and improve health outcomes by documenting social risk factors in a consistent manner.\n\nThe NCCN Distress Thermometer and Problem List is a screening tool developed by the National Comprehensive Cancer Network (NCCN) to help identify and assess distress in people with cancer. It includes a 0-10 distress rating scale and a Problem List that allows patients to indicate specific practical, emotional, physical, social, and spiritual concerns contributing to their distress.",[9],[22,23,24,25],"Centers for Medicare and Medicaid Services (CMS) survey","CMS Survey","NCCN Distress Thermometer and Problem List","National Comprehensive Cancer Network Distress Thermometer and Problem List",{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":30},"Diet Recall","A diet recall is a nutrition assessment method where an individual reports all foods and beverages consumed over a specific period, most commonly the previous 24 hours. It captures detailed information-such as portion sizes, preparation methods, and timing-to help clinicians or researchers evaluate dietary intake and identify nutritional patterns or deficiencies",[9],[31],"Food Diary",{"type":6,"name":33,"description":34,"armGroupLabels":35,"otherNames":36},"Blood Biomarker Collection","The blood specimens will be processed for plasma and buffy coat.",[9],[37],"Blood\u002FPlasma Sample",[39],{"name":40,"affiliation":41,"role":42},"Nicole Simone, MD","Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University","PRINCIPAL_INVESTIGATOR",[44],{"name":40,"role":45,"phone":46,"phoneExt":10,"email":47},"CONTACT","215-955-6702","Nicole.Simone@jefferson.edu",[49],{"facility":41,"status":50,"city":51,"state":52,"zip":53,"country":54,"countryCode":55,"cosmosGeoPoint":56,"geoPoint":61,"contacts":62},"RECRUITING","Philadelphia","Pennsylvania","19107","United States","US",{"type":57,"coordinates":58},"Point",[59,60],-75.16362,39.95238,{"lat":60,"lon":59},[63],{"name":40,"role":45,"phone":46,"phoneExt":10,"email":47},{"type":65,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100629695","exploring-inflammation-and-social-determinants-study-in-breast-cancer-patients-100629695",false,"NCT07478016","EXploring Inflammation and Social deTerminants Study in Breast Cancer Patients","EXploring Inflammation and Social deTerminants (EXIST) Study in Breast Cancer Patients","EXIST","Inclusion Criteria:\n\n* Individuals must meet all the following inclusion criteria to be eligible to participate in the study:\n\n  1. Female\n  2. \\>18 years old at time of consent\n  3. Biopsy proven invasive breast cancer or ductal carcinoma in situ\n  4. Candidate has not yet received cancer therapy for their breast cancer diagnosis\n  5. ECOG Performance Status \\\u003C 2\n  6. Able to provide consent\n  7. Must be English speaking\n\nExclusion Criteria:\n\n* An individual who meets any of the following criteria will be excluded from participation in this study:\n\n  1. Patient has started therapy or already had definitive oncologic surgery\n  2. Another malignancy within the past 6 months that was not a non-melanomatous skin lesion","FEMALE","18 Years",{"count":77,"type":78},200,"ESTIMATED","OBSERVATIONAL","This is a pilot trial to assess how measures of inflammation are correlated with Social Determinants of Health (SDoH) in breast cancer patients. Expected duration of subject participation is one single time point. The patients will fill out questionnaires and provide a plasma sample.",[82,83],"Breast Cancer","Ductal Carcinoma In Situ",[85,86,87,88],"Social Determinants of Health","IL-6","cytokine profile","immune marker profile","2026-03-13",{"date":91,"type":92},"2026-03-17","ACTUAL",{"date":94,"type":92},"2022-12-21",{"date":96,"type":78},"2028-12-31",{"name":5,"class":6},1]