[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100621247":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":32,"centralContacts":33,"locations":39,"responsibleParty":55,"collaborators":57,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":32,"eligibilityCriteria":67,"healthyVolunteers":63,"sex":68,"minAge":69,"maxAge":32,"enrollmentInfo":70,"targetDuration":32,"studyType":73,"phases":74,"briefSummary":76,"conditions":77,"keywords":79,"overallStatus":87,"whyStopped":32,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":97},{"fullName":5,"class":6},"University of Calgary","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Active subthreshold stochastic electrical vestibular stimulation","EXPERIMENTAL","Participants randomized to the active arm will receive subthreshold wideband stochastic electrical vestibular stimulation delivered via surface electrodes placed over the mastoid region and upper neck. Stimulation will be administered while seated in six sessions over two weeks. Each session will consist of two 20 minute stimulation blocks separated by a 5 minute rest. The current waveform will be a low amplitude stochastic signal (±0.35 mA) adjusted to remain below the threshold for overt vestibular sensations while providing continuous vestibular afferent input. Participants will be free to rest, read, or use personal devices during stimulation.",[13],"Device: Electrical Vestibular Stimulation",{"label":15,"type":16,"description":17,"interventionNames":18},"Sham electrical vestibular stimulation","SHAM_COMPARATOR","Participants randomized to the sham arm will undergo identical preparation, electrode placement, and scheduling as the active group, including six seated sessions over two weeks with two 20 minute blocks and a 5 minute rest per session. At the start of each block, the stimulator will briefly ramp up to a low current to mimic the sensation of active stimulation, then be reduced to zero current for the remainder of the session, while device indicators remain active. No therapeutic level vestibular stimulation will be delivered.",[19],"Device: Electrical Vestibular Stimulation Sham",[21,28],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Electrical Vestibular Stimulation","Subthreshold stochastic electrical vestibular stimulation delivered with a dual-channel isolated constant-current stimulator (Neursantys Inc.). Four-electrode mastoid-C4 montage; wideband stochastic current (0.001-300 Hz), ±0.35 mA (0.70 mA peak-to-peak), output sampled at 5 kHz. Two 20-minute seated stimulation blocks per session. Generates vestibular afferent activation while remaining below perceptual thresholds.",[9],[27],"Galvanic Vestibular Stimulation",{"type":22,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"Electrical Vestibular Stimulation Sham","Identical electrode placement and device setup as active electrical vestibular stimulation. Device ramps briefly, then delivers zero current for the remainder of the two 20-minute blocks. Device lights remain active to maintain masking; no vestibular stimulation is delivered after the ramp.",[15],null,[34],{"name":35,"role":36,"phone":37,"phoneExt":32,"email":38},"Ryan Peters, Ph.D.","CONTACT","403-220-7810","ryan.peters1@ucalgary.ca",[40],{"facility":41,"status":32,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Human Performance Laboratory, University of Calgary","Calgary","Alberta","T2N 1N4","Canada","CA",{"type":48,"coordinates":49},"Point",[50,51],-114.08529,51.05011,{"lat":51,"lon":50},[54],{"name":35,"role":36,"phone":37,"phoneExt":32,"email":38},{"type":56,"investigatorFullName":32,"investigatorTitle":32,"investigatorAffiliation":32,"oldNameTitle":32,"oldOrganization":32},"SPONSOR",[58],{"name":59,"class":60},"Neursantys Inc","INDUSTRY","100621247","exploring-mild-electrical-vestibular-stimulation-as-a-new-treatment-for-dizziness-and-migraine-symptoms-100621247",false,"NCT07368140","Exploring Mild Electrical Vestibular Stimulation as a New Treatment for Dizziness and Migraine Symptoms","Electrical Vestibular Stimulation as a Novel Neuromodulation Therapy for Vestibular Migraine: a Pilot Randomized Controlled Trial","Inclusion Criteria:\n\n* Clinical diagnosis of VM, according to the ICHD-3 and Barany Society criteria.\n* Experienced at least one vestibular migraine episode in the previous month.\n* Ability to provide informed consent and comply with study requirements.\n* Willingness to attend six EVS sessions over a two-week period and complete all required testing and diaries.\n* Physical ability to stand unassisted for at least one minute and walk 25 feet without assistance.\n\nExclusion Criteria:\n\n* Diagnosis of other vestibular disorders (e.g. benign paroxysmal positional vertigo, Meniere's disease, vestibular neuritis) that may confound results.\n* History of seizure disorder, epilepsy, or unexplained loss of consciousness.\n* Presence of implanted electronic medical devices, such as pacemakers or cochlear implants.\n* Pregnancy or plans to become pregnant during study period.\n* Use of vestibular suppressant or migraine prophylactic medications that cannot be paused or maintained at a stable dose during the two-week EVS intervention period. Acute use of rescue medications during a severe attack is permitted, however, participants who initiate new medication or undergo dose changes during the intervention window will be excluded from final analysis.\n* Current medical, psychiatric, or neurological condition (other than VM) that could interfere with participation.\n* Cognitive or language impairments that preclude understanding of instructions or valid completion of outcome measures.","ALL","18 Years",{"count":71,"type":72},50,"ESTIMATED","INTERVENTIONAL",[75],"NA","Vestibular migraine is a common cause of repeated dizziness, imbalance, and headaches that affects about three percent of Canadians. Many people do not find relief from current medications, leaving them with long term problems in balance and daily function. This study will test a new, non drug based treatment called electrical vestibular stimulation (EVS). EVS delivers gentle, safe electrical signals behind the ears to activate the brain's vestibular pathways.\n\nFifty adults with vestibular migraine will take part. Half will receive real stimulation, and half will receive a sham (placebo) treatment. Each participant will attend six sessions over two weeks. Around the treatment period, they will record dizziness and migraine symptoms in a daily diary and complete questionnaires and balance tests using motion sensors.\n\nThe main goal is to determine whether EVS can be delivered safely and comfortably in adults with vestibular migraine and whether participants can complete the sessions and assessments as planned. Results will also show whether symptoms or balance improve, providing essential information to design a larger clinical trial and, ultimately, develop new, accessible treatments for dizziness and migraine.",[78],"Vestibular Migraine",[23,27,78,80,81,82,83,84,85,86],"Vertigo","Dizziness","Balance and gait","Inertial Measurement Units","Motion sensitivity","Posturography","Neuromodulation","NOT_YET_RECRUITING","2026-01-20",{"date":90,"type":91},"2026-01-26","ACTUAL",{"date":93,"type":72},"2026-02-01",{"date":95,"type":72},"2029-12-31",{"name":5,"class":6},1]