[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100375696":3},{"organization":4,"armGroups":7,"interventions":23,"overallOfficials":30,"centralContacts":35,"locations":44,"responsibleParty":71,"collaborators":29,"id":74,"slug":75,"hasResults":76,"nctId":77,"briefTitle":78,"officialTitle":78,"acronym":29,"eligibilityCriteria":79,"healthyVolunteers":80,"sex":81,"minAge":82,"maxAge":83,"enrollmentInfo":84,"targetDuration":29,"studyType":87,"phases":88,"briefSummary":90,"conditions":91,"keywords":93,"overallStatus":47,"whyStopped":29,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":108},{"fullName":5,"class":6},"University Hospital of Mont-Godinne","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Motor Skill Learning (CIRCUIT)","EXPERIMENTAL","Intervention: training on the REAplan robot with a serious game based on motor skill learning (MSkL) serious game, the CIRCUIT.",[13],"Device: REAplan(R)",{"label":15,"type":16,"description":17,"interventionNames":18},"Motor control recovery (EASY)","ACTIVE_COMPARATOR","Training on the REAplan robot with a serious game that requires similar type and amount of movements but does not rely on motor skill learning (EASY), a brick buster game.",[13],{"label":20,"type":16,"description":21,"interventionNames":22},"Conventional","Training sessions with classical exercices focused on the upper limb administered by occupation therapist.",[13],[24],{"type":25,"name":26,"description":27,"armGroupLabels":28,"otherNames":29},"DEVICE","REAplan(R)","motor skill learning with the REAplan(R) rehabilitation robot, to be perfomed with the affected arm",[20,9,15],null,[31],{"name":32,"affiliation":33,"role":34},"Yves Vandermeeren, MD, PhD","UCLouvain IONS","PRINCIPAL_INVESTIGATOR",[36,40],{"name":32,"role":37,"phone":38,"phoneExt":29,"email":39},"CONTACT","+32 81 42 33 21","yves.vandermeeren@uclouvain.be",{"name":41,"role":37,"phone":42,"phoneExt":29,"email":43},"Eloïse Gerardin, MSc","+32 81 42 33 48","eloise.gerardin@uclouvain.be",[45,63],{"facility":46,"status":47,"city":48,"state":49,"zip":50,"country":51,"countryCode":52,"cosmosGeoPoint":53,"geoPoint":58,"contacts":59},"CHU UCL Namur","RECRUITING","Yvoir","Namur","5530","Belgium","BE",{"type":54,"coordinates":55},"Point",[56,57],4.88059,50.3279,{"lat":57,"lon":56},[60],{"name":61,"role":37,"phone":62,"phoneExt":29,"email":43},"Eloïse Gerardin","+3281423348",{"facility":64,"status":65,"city":48,"state":29,"zip":50,"country":51,"countryCode":52,"cosmosGeoPoint":66,"geoPoint":68,"contacts":69},"University Hospital CHU Dinant Godinne UCL","NOT_YET_RECRUITING",{"type":54,"coordinates":67},[56,57],{"lat":57,"lon":56},[70],{"name":32,"role":37,"phone":29,"phoneExt":29,"email":39},{"type":34,"investigatorFullName":72,"investigatorTitle":73,"investigatorAffiliation":5,"oldNameTitle":29,"oldOrganization":29},"Pr Yves Vandermeeren, MD, PhD","Principal Investigator","100375696","exploring-motor-learning-in-acute-stroke-through-robotics-100375696",false,"NCT04171856","Exploring Motor Learning in Acute Stroke Through Robotics","ACUTE STROKE PATIENTS:\n\nInclusion Criteria:\n\n* acute stroke (\\> 21 days)\n* aged 18-90 years\n* with a stroke lesion on brain imaging\n\nExclusion Criteria:\n\n* \" classical \" contre-indication to MRI (non-MR-compatible pacemaker, pregnancy, non-MR-compatible implanted devices, claustrophoby, etc ...)\n* difficulty in understanding or executing commands\n* drug\u002Falcohol abuse\n* severe aphasia \u002F cognitive deficits interfering with study\n* inability to voluntarily move the affected arm (i.e. complete paralysis of the arm)\n* multiple strokes \u002F dementia \u002F psychiatric condition\n\nPATIENTS WITH TRANSIENT GLOBAL AMNESIA:\n\nClinical diagnosis, criteria of Hodge \\& Warlow (1990):\n\n* Anterograde amnesia observed by a witness\n* No alteration of consciousness or loss of identity\n* Cognitive dysfunction limited to amnesia\n* Lack of focused neurological deficit or argument for a comitiality\n* Absence of head trauma\n* Symptom resolution within 24 hours\n* Possible existence of vegetative symptoms\n\nInclusion criteria:\n\n* Transient global amnesia\n* 8-90 years old\n* Be able to perform 3 consecutive sessions on a rehabilitation robot\n\nExclusion criteria:\n\n* Severe aphasia \u002F cognitive deficits interfering with study\n* Psychiatric disorders\n* Alcohol \u002F drug addiction\n* Exclusion criteria related to MRI\n\nHEALTHY INDIVIDUALS:\n\nInclusion Criteria:\n\n• 18-90 years\n\nExclusion Criteria:\n\n* medical history with a previous stroke\u002Fneurological deficit\n* drug\u002Falcohol abuse\n* psychiatric condition\u002F dementia\n\nCHRONIC STROKE PATIENTS:\n\nInclusion Criteria:\n\n* chronic stroke (\\>6 months)\n* aged 18-90 years\n* with a stroke lesion on brain imaging\n\nExclusion Criteria:\n\n* difficulty in understanding or executing commands\n* drug\u002Falcohol abuse\n* severe aphasia \u002F cognitive deficits interfering with study\n* inability to voluntarily move the affected arm (i.e. complete paralysis of the arm)\n* multiple strokes \u002F dementia \u002F psychiatric condition",true,"ALL","18 Years","90 Years",{"count":85,"type":86},245,"ESTIMATED","INTERVENTIONAL",[89],"NA","The acute phase of stroke is characterized by an enhancement of neural plasticity which supports rapid motor recovery. It is unclear whether acute stroke patients can acquire new motor skills with their affected upper limb. The aims of this research program are:\n\n1. To test the capacity of acute stroke patients (\\\u003C 21 days) to learn and retain a complex unimanual motor skill.\n2. To explore whether acute stroke to different brain regions (quantified with brain MRI) induces specific deficits in motor skill learning.\n3. To compare acute stroke patients with healthy individuals and with chronic stroke patients.",[92],"Stroke, Acute",[94,95,96,97,98],"Acute stroke","Motor skill learning","Upper limb","Rehabilitation","Subacute stroke","2025-03-31",{"date":101,"type":102},"2025-04-03","ACTUAL",{"date":104,"type":102},"2020-01-01",{"date":106,"type":86},"2040-07-01",{"name":5,"class":6},2]