[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100617031":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":24,"locations":34,"responsibleParty":48,"collaborators":19,"id":50,"slug":51,"hasResults":52,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":56,"eligibilityCriteria":57,"healthyVolunteers":58,"sex":59,"minAge":60,"maxAge":19,"enrollmentInfo":61,"targetDuration":19,"studyType":64,"phases":65,"briefSummary":67,"conditions":68,"keywords":19,"overallStatus":71,"whyStopped":19,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":81},{"fullName":5,"class":6},"University of Nottingham","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Resistance exercise training plus high-intensity interval training (ReHIIT) Intervention","EXPERIMENTAL","Participants will complete 8-12 supervised sessions combining high-intensity interval cycling and resistance training at 70% 1-RM.",[13],"Other: ReHIIT Training Intervention",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":19},"ReHIIT Training Intervention","Participants will complete 8-12 supervised sessions combining high-intensity interval cycling (5 × 1-minute intervals at 110% CPET wattage, with 90-second rest intervals) and resistance training at 70% 1-RM (3 sets of 8-12 repetitions, 6 exercises).",[9],null,[21],{"name":22,"affiliation":5,"role":23},"Professor Bethan E Phillips","PRINCIPAL_INVESTIGATOR",[25,30],{"name":26,"role":27,"phone":28,"phoneExt":19,"email":29},"Tyler J Daubrah-Scott, MRes, BSc (Hons)","CONTACT","01332 724676","tyler.daubrah-scott@nottingham.ac.uk",{"name":31,"role":27,"phone":32,"phoneExt":19,"email":33},"Wayne Fradley, BMBS (hons) MRCS (2022)","01332 724640","wayne.fradley@nottingham.ac.uk",[35],{"facility":36,"status":19,"city":37,"state":38,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":19},"Medical School, University of Nottingham, Royal Derby Hospital","Derby","Derbyshire","DE223DT","United Kingdom","UK",{"type":43,"coordinates":44},"Point",[45,46],-1.47663,52.92277,{"lat":46,"lon":45},{"type":49,"investigatorFullName":19,"investigatorTitle":19,"investigatorAffiliation":19,"oldNameTitle":19,"oldOrganization":19},"SPONSOR","100617031","exploring-resistance-exercise-training-plus-high-intensity-interval-training-rehiit-as-cancer-prehabilitation-100617031",false,"NCT07313332","Exploring Resistance Exercise Training Plus High-Intensity Interval Training (ReHIIT) as Cancer Prehabilitation","Exploring Resistance Exercise Training Plus High-Intensity Interval Training (ReHIIT) as Cancer Prehabilitation: A Healthy Control Group Pilot Study","ReHIIT_CON","Inclusion Criteria:\n\n* Participant is willing and able to give informed consent for participation in the study.\n* Availability and willingness to attend the Royal Derby Hospital site for a minimum of 8 exercise sessions and 2 assessment sessions across the study period.\n\nExclusion Criteria:\n\n* BMI \\\u003C18 or \\>35 kg\u002Fm2\n* Known active cance\n* Known metabolic disease\n* Current known neurological or musculoskeletal conditions (e.g. epilepsy)\n* Active known cardiovascular, cerebrovascular or respiratory disease - e.g:\n* Uncontrolled hypertension (systolic BP \\> 160 mmHg or diastolic BP \\>100 mmhg)\n* Myocardial infarction within the last 6 months or unstable angina\n* Heart failure (New York Heart association Class III\u002FIV)\n* Arrhythmia\n* Right to left cardiac shunt\n* Aneurysm of a named blood vessel\n* COPD\n* Pulmonary hypertension\n* Exercise-induced or brittle asthma\n* Previous stroke\u002Ftransient ischaemic attack\n* Abnormal ECG results (at the discrepancy of the study doctor)\n* Patients who are unable to undergo CPET based on ATS\u002FACSS guidelines \\^\n* Pre-existing clotting disorder known to the participant or anticoagulant use\n* Family history of severe bleeding requiring medical intervention\n* Participation in a research study in the last 3 months involving invasive procedures or an inconvenience allowance (ALL UoN FMHS UREC approved studies)\n* Pregnant or breastfeeding",true,"ALL","18 Years",{"count":62,"type":63},14,"ESTIMATED","INTERVENTIONAL",[66],"NA","Colorectal cancer is the fourth most common cancer in the UK. Prehabilitation, including exercise, can improve recovery from surgery. This pilot study investigates the combined effects of resistance and high-intensity interval training (ReHIIT) in healthy adults to establish baseline physiology and responses for comparison with cancer patients",[69,70],"Healthy Adult Male and Female Volunteers","Intervention","NOT_YET_RECRUITING","2025-12-16",{"date":74,"type":75},"2025-12-31","ACTUAL",{"date":77,"type":63},"2026-01-01",{"date":79,"type":63},"2027-12-01",{"name":5,"class":6},1]