[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100639341":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":30,"locations":36,"responsibleParty":52,"collaborators":54,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":64,"acronym":26,"eligibilityCriteria":65,"healthyVolunteers":62,"sex":66,"minAge":67,"maxAge":26,"enrollmentInfo":68,"targetDuration":26,"studyType":71,"phases":72,"briefSummary":74,"conditions":75,"keywords":77,"overallStatus":38,"whyStopped":26,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"Florida Atlantic University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Intervention Arm","EXPERIMENTAL","The Exercise + transcranial alternating current stimulation (Ex+tACS) group will complete a four-week intervention consisting of 3 days\u002Fweek of 30 minutes of aerobic exercise on a treadmill at a sustained moderate intensity, immediately followed by 15 min of tACS. During tACS, 6Hz alternating current stimulation will be administered to participants' prefrontal cortex (forehead region) using a tACS while the participant completes the AX Continuous Performance Test (AX-CPT).",[13],"Behavioral: Exercise + transcranial alternating current stimulation (Ex+tACS)",{"label":15,"type":16,"description":17,"interventionNames":18},"Control","SHAM_COMPARATOR","The Sham Comparator group will complete 30 minutes of aerobic exercise on the treadmill followed by the Sustained Attention-Continuous Performance Task (AX-CPT) with a sham transcranial alternating current stimulation (tACS) condition. The same procedures will be followed regarding the tACS, but stimulation will only last one minute, ramping up and down at the beginning and end of the 15-minute period, simulating the periodic tingling sensation that are reported with tACS.",[19],"Behavioral: Control",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"BEHAVIORAL","Exercise + transcranial alternating current stimulation (Ex+tACS)","The Ex+tACS group will complete a four-week intervention consisting of 3 days\u002Fweek of 30 minutes of aerobic exercise on a treadmill at a sustained moderate intensity, immediately followed by 15 min of tACS while completing the AX Continuous Performance Test (AX-CPT).",[9],null,{"type":22,"name":15,"description":28,"armGroupLabels":29,"otherNames":26},"The Control (CON) group will complete 30 minutes of aerobic exercise on the treadmill followed by the Sustained Attention-Continuous Performance Task (AX-CPT) with a sham tACS condition. After each session, both the EX+tACS and control participants will complete a questionnaire regarding experience with tACS.",[15],[31],{"name":32,"role":33,"phone":34,"phoneExt":26,"email":35},"Ashley L Artese, PhD","CONTACT","856-534-8926","aartese@fau.edu",[37],{"facility":5,"status":38,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"RECRUITING","Boca Raton","Florida","33431","United States","US",{"type":45,"coordinates":46},"Point",[47,48],-80.0831,26.35869,{"lat":48,"lon":47},[51],{"name":32,"role":33,"phone":34,"phoneExt":26,"email":35},{"type":53,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR",[55,57],{"name":56,"class":6},"Memorial Sloan Kettering Cancer Center",{"name":58,"class":59},"Florida Department of Health","OTHER_GOV","100639341","exploring-the-feasibility-of-an-exercise-and-noninvasive-brain-stimulation-intervention-in-breast-cancer-survivors-100639341",false,"NCT07587957","Exploring the Feasibility of an Exercise and Noninvasive Brain Stimulation Intervention in Breast Cancer Survivors","Inclusion Criteria:\n\n* Breast cancer survivors (≥18 years) will be eligible to participate if the following inclusion criteria is met:\n* Diagnosed non-metastatic breast cancer (stages 0-3)\n* Completed primary breast cancer treatment (surgery, chemotherapy, radiation) for at least 3 months\n* Self-reported cognitive impairment after cancer treatment\n\nExclusion Criteria:\n\n* Current participation in aerobic exercise for ≥60 min\u002Fwk\n* Contraindication or impairment that precludes the potential participant from exercise as defined by the American College of Sports Medicine\n* The presence of serious medical illnesses, metal implants, previous brain trauma, epilepsy or history of seizures, previous surgery to the head or spinal cord, or skin problems at the forehead area where the tACS electrodes will be applied\n* Uncontrolled cardiovascular disease\n* Functional impairments or physical condition that would make exercise unsafe\n* Metastatic cancer or diagnosis of a different cancer (excluding melanoma) within the past 5 years\n* Contraindication to exercise a defined by the American College of Sports Medicine","ALL","18 Years",{"count":69,"type":70},40,"ESTIMATED","INTERVENTIONAL",[73],"NA","The purpose of this study is to assess the feasibility of a 4-week intervention combining exercise and transcranial alternating current stimulation (Ex+tACS) in breast cancer survivors who report experiencing cancer-related cognitive impairment. Feasibility will be assessed by measuring participant retention, adherence, satisfaction with the intervention, and safety. The researchers will also examine pre-to-post intervention changes in attention, executive function, working memory, perceived cognitive function, and physical function before, after, and four weeks post intervention completion in the Ex+tACS group compared to a control group who will receive exercise and a placebo tACS condition (CON).",[76],"Breast Cancer",[76,78,79,80],"Cancer-related cognitive impairment","Non-invasive brain stimulation","Exercise","2026-05-07",{"date":83,"type":84},"2026-05-14","ACTUAL",{"date":86,"type":84},"2026-01-07",{"date":88,"type":70},"2027-01-01",{"name":5,"class":6},1]