[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100527575":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":26,"centralContacts":34,"locations":39,"responsibleParty":56,"collaborators":23,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":62,"acronym":63,"eligibilityCriteria":64,"healthyVolunteers":60,"sex":65,"minAge":66,"maxAge":23,"enrollmentInfo":67,"targetDuration":23,"studyType":70,"phases":71,"briefSummary":73,"conditions":74,"keywords":76,"overallStatus":42,"whyStopped":23,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"Cancer Trials Ireland","NETWORK",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Control","EXPERIMENTAL","* High protein, high energy diet\n* Fish oil supplement (ProSure®)\n* Pancreatic Enzymes (Creon®)\n* A daily individualised step target (10% above your own baseline)\n* Four scheduled appointments with a dietitian",[13],"Dietary Supplement: Control",{"label":15,"type":10,"description":16,"interventionNames":17},"Intervention","* High protein, high energy diet\n* Fish oil supplement (ProSure®)\n* Pancreatic Enzymes (Creon®)\n* A daily individualised step target (10% above your own baseline)\n* Seven scheduled appointments with a dietitian\n* Six scheduled appointments with a physiotherapist",[18],"Dietary Supplement: Intervention",[20,24],{"type":21,"name":9,"description":11,"armGroupLabels":22,"otherNames":23},"DIETARY_SUPPLEMENT",[9],null,{"type":21,"name":15,"description":16,"armGroupLabels":25,"otherNames":23},[15],[27,31],{"name":28,"affiliation":29,"role":30},"Oonagh Griffin, Dr","SVUH\u002FUniversity College Dublin","PRINCIPAL_INVESTIGATOR",{"name":32,"affiliation":33,"role":30},"Ray McDermott, Prof","St Vincent's University Hospital, Ireland",[35],{"name":5,"role":36,"phone":37,"phoneExt":23,"email":38},"CONTACT","+35316677211","info@cancertrials.ie",[40],{"facility":41,"status":42,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"St Vincent's University Hospital","RECRUITING","Dublin","Leinster","D04 T6F4","Ireland","IE",{"type":49,"coordinates":50},"Point",[51,52],-6.24889,53.33306,{"lat":52,"lon":51},[55],{"name":32,"role":36,"phone":23,"phoneExt":23,"email":23},{"type":57,"investigatorFullName":23,"investigatorTitle":23,"investigatorAffiliation":23,"oldNameTitle":23,"oldOrganization":23},"SPONSOR","100527575","exploring-the-impact-of-a-multi-modal-nutritional-intervention-in-patients-undergoing-chemotherapy-for-pancreatic-cancer-feed-trial-100527575",false,"NCT06149546","Exploring the Impact of a Multi-modal Nutritional Intervention in Patients Undergoing Chemotherapy for Pancreatic Cancer (FEED Trial)","FEED","Inclusion Criteria:\n\n1. Ability to give signed informed consent and willing and able to comply with the protocol.\n2. Patients aged 18 years and above.\n3. Patients with newly diagnosed, pathologically confirmed pancreatic ductal adenocarcinoma who will undergo neoadjuvant chemotherapy following formal MDT assessment at St Vincent's University Hospital, specifically FOLFIRINOX or Gemcitabine with Nab-Paclitaxel (and\u002For any additional therapy regimen approved by NCCP).\n4. Patients have CT scan available and suitable for body composition analysis within 8 weeks prior to randomisation.\n5. Patients have adequate upper limb dexterity to allow assessment of hand grip strength.\n\nExclusion Criteria:\n\n1. Patients who are unable to consume oral diet and require prolonged enteral and\u002For parenteral nutritional support.\n2. Patient with any significant history of non-compliance to medical treatments or with inability to grant reliable informed consent.\n3. Patients who can\u002Fwill not consume fish and pork products due to allergy, intolerance, religious beliefs, or dietary preferences.\n4. Patients with known blood clotting disorders, e.g antiphospholipid syndrome, factor V Leiden syndrome, haemophilia \u002Fany liver disease which has progressed to liver cirrhosis where prolonged fish oil supplementation is unsafe.\n5. Patients with uncontrolled hypertension (BP \\>180\u002F110 mm Hg) which prohibits exercise.\n6. Patients with muscle wasting disorders, e.g. paraplegia, motor neuron disease, Duchenne muscular dystrophy, multiple sclerosis.\n7. Women who are pregnant or breastfeeding due to differing nutritional needs and macronutrient metabolism.","ALL","18 Years",{"count":68,"type":69},70,"ESTIMATED","INTERVENTIONAL",[72],"NA","The study will examine if a multi-modal nutritional care package, with or without resistance training delivered with neoadjuvant chemotherapy, is effective at preventing loss of muscle strength during neoadjuvant chemotherapy for pancreatic cancer. There are two arms in this study: Control Arm will receive standard dietetic care and be prescribed standard pancreatic enzyme replacement therapy and oral nutritional supplement drinks with their neoadjuvant chemotherapy. The intervention Arm will have 3 additional dietitian visits and 6 physiotherapist visits that the control group will not.",[75],"Pancreatic Cancer",[75,77],"Multi-modal Nutritional","2025-07-04",{"date":80,"type":81},"2025-07-08","ACTUAL",{"date":83,"type":81},"2024-05-01",{"date":85,"type":69},"2028-11",{"name":5,"class":6},1]