[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100581254":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":30,"locations":36,"responsibleParty":53,"collaborators":26,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":26,"eligibilityCriteria":61,"healthyVolunteers":62,"sex":63,"minAge":64,"maxAge":65,"enrollmentInfo":66,"targetDuration":26,"studyType":69,"phases":70,"briefSummary":72,"conditions":73,"keywords":26,"overallStatus":39,"whyStopped":26,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"Wecare Probiotics Co., Ltd.","INDUSTRY",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Probiotic group","ACTIVE_COMPARATOR","Bacterial count: ≥1000 billion CFUs per bottle Take one bottle of yogurt per day for 3 weeks",[13],"Dietary Supplement: Probiotic yogurt group",{"label":15,"type":16,"description":17,"interventionNames":18},"Placebo group","PLACEBO_COMPARATOR","Product name: placebo yogurt Take one bottle of yogurt per day for 3 weeks",[19],"Dietary Supplement: Yogurt control group",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DIETARY_SUPPLEMENT","Probiotic yogurt group","The intervention phase of this study will last 3 weeks, and each participant will make 3 visits (week 0, week 1, week 3).",[9],null,{"type":22,"name":28,"description":24,"armGroupLabels":29,"otherNames":26},"Yogurt control group",[15],[31],{"name":32,"role":33,"phone":34,"phoneExt":26,"email":35},"Ying Jin, Doctor","CONTACT","13375163966","sunny13211@sina.com",[37],{"facility":38,"status":39,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Suzhou Ninth People's Hospital Suzhou Ninth Hospital affiliated to Soochow University","RECRUITING","Suzhou","Jiangsu","215200","China","CN",{"type":46,"coordinates":47},"Point",[48,49],120.59538,31.30408,{"lat":49,"lon":48},[52],{"name":32,"role":33,"phone":26,"phoneExt":26,"email":35},{"type":54,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100581254","exploring-the-potential-benefits-of-probiotic-yogurt-100581254",false,"NCT06847919","Exploring the Potential Benefits of Probiotic Yogurt","Exploring the Potential Benefits of High-activity Probiotic Yogurt: a Randomized, Double-blind, Placebo-controlled Trial","Inclusion Criteria:\n\n1. Meet the Rome IV diagnosis criteria for chronic constipation;\n2. Patients who are able to understand clinical studies and are committed to complying with study requirements and procedures;\n3. Age 18-65. -\n\nExclusion Criteria:\n\n1. Systemic (diabetes, autoimmune diseases, cancer), gastrointestinal or liver diseases known to be associated with alterations in the gut microbiota;\n2. Patients who are pregnant or lactating;\n3. have taken antimicrobials, probiotics, or drugs that inhibit stomach acid or gastrointestinal motility in the past 6 weeks;\n4. Patients who changed their diet type during the study;\n5. Patients who are allergic or intolerant to any component of the investigational product formulation;\n6. Patients with cardiovascular, cerebrovascular, liver, kidney and hematopoietic system and other serious diseases and endocrine diseases, mental patients;\n7. Stop taking the tested sample or add other drugs in the middle, unable to judge the efficacy or incomplete data;\n8. short-term use of objects related to the function of the test, affecting the judgment of the result;\n9. have been dieting, exercising excessively, taking weight loss medications or taking medications that may affect appetite in the past 3 months;\n10. Current or past excessive use of alcohol, drugs, or supplements that may cause intestinal dysfunction or interfere with the evaluation of the efficacy of the study product -",true,"ALL","18 Years","65 Years",{"count":67,"type":68},84,"ESTIMATED","INTERVENTIONAL",[71],"NA","This study aims to evaluate the effect of a high-activity probiotic yogurt on improving symptoms of chronic constipation, observing its regulatory effects on the gut microbiota and the incidence of adverse reactions in study participants over a 21-day intervention period.",[74],"Chronic Constipation","2025-03-02",{"date":77,"type":78},"2025-03-05","ACTUAL",{"date":80,"type":68},"2025-02-25",{"date":82,"type":68},"2025-12-30",{"name":5,"class":6},1]