[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100645061":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":10,"centralContacts":17,"locations":26,"responsibleParty":43,"collaborators":10,"id":45,"slug":46,"hasResults":47,"nctId":48,"briefTitle":49,"officialTitle":49,"acronym":50,"eligibilityCriteria":51,"healthyVolunteers":52,"sex":53,"minAge":54,"maxAge":10,"enrollmentInfo":55,"targetDuration":10,"studyType":58,"phases":59,"briefSummary":61,"conditions":62,"keywords":10,"overallStatus":64,"whyStopped":10,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":74},{"fullName":5,"class":6},"Centre Hospitalier Universitaire de Nice","OTHER",[8],{"label":9,"type":6,"description":10,"interventionNames":11},"Exposome assessment",null,[12],"Other: Exposome assessment",[14],{"type":6,"name":9,"description":15,"armGroupLabels":16,"otherNames":10},"Visit 1: blood sample, questionnaires on the personal exposome (lifestyle habits (e.g., physical activity, diet, stress) and social characteristics and health status) \\| ii) Outpatient assessment: wearing a silicone bracelet for 7 days to measure external environmental exposure to pollutants and quantify physical activity \\| iii) Visit 2: 1-year follow-up of health status",[9],[18,23],{"name":19,"role":20,"phone":21,"phoneExt":10,"email":22},"Olivier GUERIN, PROFESSOR","CONTACT","0492034194","guerin.o@chu-nice.fr",{"name":24,"role":20,"phone":10,"phoneExt":10,"email":25},"Virginie PIOVANO","piovano.v@chu-nice.fr",[27],{"facility":28,"status":10,"city":29,"state":10,"zip":10,"country":30,"countryCode":31,"cosmosGeoPoint":32,"geoPoint":37,"contacts":38},"CHU de Nice - Hopital de Cimiez","Nice","France","FR",{"type":33,"coordinates":34},"Point",[35,36],7.26608,43.70313,{"lat":36,"lon":35},[39,41],{"name":40,"role":20,"phone":21,"phoneExt":10,"email":22},"Olivier GUERIN, Pr",{"name":40,"role":42,"phone":10,"phoneExt":10,"email":10},"PRINCIPAL_INVESTIGATOR",{"type":44,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100645061","exposome-pollutants-biology-in-the-older-subject-exposage-100645061",false,"NCT07678528","Exposome, Pollutants, Biology in the Older Subject: EXPOSAGE","EXPOSAGE","Inclusion Criteria:\n\n* Aged 55 or over\n* Affiliated with or beneficiaries of a social security scheme\n* Signed the informed consent form •-Persons residing in one of the following municipalities : Antibes, Le Bar-sur-Loup, Berre-les-Alpes, Beuil, Blausasc, Breil-sur-Roya, Cabris, Cannes, Carros, Clans, Contes, Drap, L'Escarène, Escragnolles, Fontan, La Gaude, Gilette, Grasse, Lantosque, Levens, Nice, Peillon, Peymeinade, Saint-André-de-la-Roche, Saint-Etienne-de-Tinée, Sospel, Tourrettes-sur-Loup, Vence, Tende\n\nExclusion Criteria:\n\n* patients currently undergoing intensive drug treatment, including chemotherapy",true,"ALL","55 Years",{"count":56,"type":57},400,"ESTIMATED","INTERVENTIONAL",[60],"NA","Numerous factors, both individual and environmental, can influence aging, an individual's health, and their functional status. However, the understanding of the combined impact of lifestyle-related exposures (e.g., physical activity, diet, sleep) (personal external exposome), exposures to pollutants (environmental external exposome), and their biological responses (internal exposome)-in other words, the impact of the \"exposome\" on healthy aging-remains limited, particularly in characterizing the molecular mechanisms associated with these interactions. Exposome approaches identifying key exposures and molecular mechanisms could lead to a better understanding of how the environment, interacting with health behaviors, can affect functional status. Thus, the objective of this study is i) to evaluate the links between the external exposome, the internal exposome and the health of older and aging individuals, and ii) to identify biological markers associated with a vulnerable health status in older and aging individuals.",[63],"Aging Disorder","NOT_YET_RECRUITING","2026-06-24",{"date":67,"type":68},"2026-07-01","ACTUAL",{"date":70,"type":57},"2030-09",{"date":72,"type":57},"2031-09",{"name":5,"class":6},1]