[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100566321":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":22,"centralContacts":27,"locations":37,"responsibleParty":57,"collaborators":59,"id":63,"slug":64,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":67,"acronym":68,"eligibilityCriteria":69,"healthyVolunteers":65,"sex":70,"minAge":71,"maxAge":72,"enrollmentInfo":73,"targetDuration":10,"studyType":76,"phases":10,"briefSummary":77,"conditions":78,"keywords":81,"overallStatus":39,"whyStopped":10,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":97},{"fullName":5,"class":6},"Centre Hospitalier Universitaire de la Guadeloupe","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"peripubertal children",null,"Children born from a mother whose pregnancy was included in the Timoun cohort (2004 -2007).",[13],"Other: Clinical examination",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":19},"Clinical examination","For the aim of the present study, we will follow-up children born alive in the TIMOUN cohort at peripubertal age. Questionnaires will be administered to parents on the child's health and lifestyle. Stature-weight anthropometric and cardio-dynamic measurements of the child will be obtained. Scores on three cognitive tests will be obtained. Furthermore, steroid hormones and chlordecone in the child's peripheral blood will be determined.",[9],[20,21],"Blood collection,","cognitive tests",[23],{"name":24,"affiliation":25,"role":26},"Gulen AYHAN","CHU of Guadeloupe","PRINCIPAL_INVESTIGATOR",[28,33],{"name":29,"role":30,"phone":31,"phoneExt":10,"email":32},"Valérie HAMONY-SOTER","CONTACT","+590 590 93 46 77","valerie.soter@chu-guadeloupe.fr",{"name":34,"role":30,"phone":35,"phoneExt":10,"email":36},"Eunice NUBRET","+590 590 93 46 86","eunice.nubret@chu-guadeloupe.fr",[38],{"facility":25,"status":39,"city":40,"state":41,"zip":42,"country":41,"countryCode":10,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"RECRUITING","Pointe-à-Pitre","Guadeloupe","97159",{"type":44,"coordinates":45},"Point",[46,47],-61.53459,16.23638,{"lat":47,"lon":46},[50,53],{"name":24,"role":30,"phone":51,"phoneExt":10,"email":52},"+590 590 89 43 80","gulen.ayhan@chu-guadeloupe.fr",{"name":54,"role":30,"phone":55,"phoneExt":10,"email":56},"Luc MULTIGNER","+33 (0) 6 09 41 91 01","luc.multigner@inserm.fr",{"type":58,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[60],{"name":61,"class":62},"Institut National de la Santé Et de la Recherche Médicale, France","OTHER_GOV","100566321","exposure-to-organochlorine-pollutants-and-impact-on-development-in-the-peripubertal-age-in-guadeloupe-100566321",false,"NCT06653660","Exposure to Organochlorine Pollutants and Impact on Development in the Peripubertal Age in Guadeloupe","TIMOUNPUBERTY","Inclusion Criteria:\n\n* Be born to a mother whose pregnancy was included in the Timoun cohort (2004 - 2007) and whose parents agreed to be contacted later.\n* Residing in Guadeloupe at the peripubertal age\n* Affiliation to a social security scheme\n* Agreement to participate in the study and informed consent signed by the minor\n* Study participation agreement and informed consent signed by the parents\n\nExclusion Criteria:\n\n* Refusal to participate in the research","ALL","16 Years","22 Years",{"count":74,"type":75},650,"ESTIMATED","OBSERVATIONAL","In the context of environmental pollution of the French West Indies by chlordecone and questions about health consequences, monitoring at the peripubertal age of children born alive in the TIMOUN cohort is justified in several respects: - existence of an already established mother-child cohort whose live-born children will reach peripubertal ages during the period 2020-2022; - opportunity to verify hypotheses put forward on the basis of toxicological data acquired in laboratory animals and the hormonal characteristics of chlordecone (endocrine disruptor); - strong societal demand for such research to be carried out because of concerns about the sensitivity of children and adolescents to the effects of environmental xenobiotics, in particular on sexual development and the age of puberty; - recommendation of the Scientific Council Chlordecone Inserm - InVS; specific action of the National Plan Chlordecone IV.",[79,80],"Prenatal Exposure","Postnatal Exposure",[79,80,82,83,84,85,86,41,87],"Chlordecone","Persistent Organic Pollutants","Endocrine disruptors","Puberty","Development","French West Indies","2025-11-14",{"date":90,"type":91},"2025-11-17","ACTUAL",{"date":93,"type":91},"2022-12-19",{"date":95,"type":75},"2026-12-19",{"name":5,"class":6},1]