[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100632140":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":37,"centralContacts":38,"locations":48,"responsibleParty":139,"collaborators":142,"id":146,"slug":147,"hasResults":148,"nctId":149,"briefTitle":150,"officialTitle":151,"acronym":152,"eligibilityCriteria":153,"healthyVolunteers":148,"sex":154,"minAge":155,"maxAge":37,"enrollmentInfo":156,"targetDuration":37,"studyType":159,"phases":160,"briefSummary":162,"conditions":163,"keywords":165,"overallStatus":171,"whyStopped":37,"lastUpdateSubmitDate":172,"lastUpdatePostDateStruct":173,"startDateStruct":176,"completionDateStruct":178,"leadSponsor":180,"locationsCount":181},{"fullName":5,"class":6},"Hospital Clinic of Barcelona","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Extended (Long)-Prehabilitation","EXPERIMENTAL","Patients allocated to the extended prehabilitation will constitute the experimental group. These patients will receive multimodal prehabilitation including but not limtied to exercise training, nutritional optimization and psychological support from start of neoadjuvant therapy until surgery",[13],"Behavioral: Extended (Long)-Prehabilitation",{"label":15,"type":16,"description":17,"interventionNames":18},"Standard (Short)-Prehabilitation","ACTIVE_COMPARATOR","Patients allocated to the standard prehabilitation will act as active comparator. In this group, patients will receive only general recommendations and tips during neoadjuvant therapy followed by standard prehabilitation until surgery.",[19],"Behavioral: Standard (Short)-Prehabilitation",[21,30],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","In this study, multimodal prehabilitation will be delivered throughout the course of neoadjuvant therapy and until surgery in the Extended-Prehabilitation arm, while the control group will only receive the intervention once neoadjuvant therapy is completed and the indication for surgery has been confirmed by the multidisciplinary tumour board.\n\nThe intervention will consist of three major pillars: a) supervised (virtual or facility-based) exercise training twice a week; b) individual nutritional counselling and supplementation; c) individual or group-based support based on the needs and preferences of the patients. Additional interventions according to the centre standard of care such as iron optimization and smoking cessation will be provided if needed.",[9],[26,27,28,29],"Nutritional optimization","Psychological Support","Perioperative care","Exercise Therapy",{"type":22,"name":15,"description":31,"armGroupLabels":32,"otherNames":33},"Standard (short) prehabilitation will include the same three pillars (exercise training twice weekly, individual nutritional counselling and supplementation and psychological support delivered only at the end of neoadjuvant therapy and until surgery (approximately 3-4 weeks). Additional interventions such as smoking cessation and iron optimization will also be included if deemed neccessary in accordance with hospitals' standard of care",[15],[34,35,36,27],"Perioperative Care","Preoperative Exercise","Nutritional Optimization",null,[39,44],{"name":40,"role":41,"phone":42,"phoneExt":37,"email":43},"Berta Díaz Feijoo, PhD","CONTACT","0034 932275400","bdiazfe@clinic.cat",{"name":45,"role":41,"phone":46,"phoneExt":37,"email":47},"Raquel Sebio Garcia, PhD","0034 634787194","sebio@clinic.cat",[49,71,87,104,122],{"facility":50,"status":37,"city":51,"state":52,"zip":53,"country":54,"countryCode":55,"cosmosGeoPoint":56,"geoPoint":61,"contacts":62},"Hospital Universitario Germans Trias i Pujol","Badalona","Barcelona","08916","Spain","ES",{"type":57,"coordinates":58},"Point",[59,60],2.24741,41.45004,{"lat":60,"lon":59},[63,67,69],{"name":64,"role":41,"phone":65,"phoneExt":37,"email":66},"Enrique Moret, PhD","0034 934651200","emoret.germanstrias@gencat.cat",{"name":64,"role":68,"phone":37,"phoneExt":37,"email":37},"SUB_INVESTIGATOR",{"name":70,"role":68,"phone":37,"phoneExt":37,"email":37},"Sergio Martínez, PhD",{"facility":5,"status":37,"city":52,"state":52,"zip":72,"country":54,"countryCode":55,"cosmosGeoPoint":73,"geoPoint":77,"contacts":78},"08036",{"type":57,"coordinates":74},[75,76],2.15899,41.38879,{"lat":76,"lon":75},[79,80,82,83,85],{"name":45,"role":41,"phone":46,"phoneExt":37,"email":47},{"name":40,"role":81,"phone":37,"phoneExt":37,"email":37},"PRINCIPAL_INVESTIGATOR",{"name":45,"role":81,"phone":37,"phoneExt":37,"email":37},{"name":84,"role":68,"phone":37,"phoneExt":37,"email":37},"Núria Carreras Dieguez, PhD",{"name":86,"role":68,"phone":37,"phoneExt":37,"email":37},"Graciela Martínez-Pallí, PhD",{"facility":88,"status":37,"city":89,"state":89,"zip":90,"country":54,"countryCode":55,"cosmosGeoPoint":91,"geoPoint":95,"contacts":96},"Hospital Universitario 12 de Octubre","Madrid","28041",{"type":57,"coordinates":92},[93,94],-3.70256,40.4165,{"lat":94,"lon":93},[97,101,102],{"name":98,"role":41,"phone":99,"phoneExt":37,"email":100},"Álvaro Tejerizo, PhD","0034 913908000","alvaro.tejerizo@salud.madrid.org",{"name":98,"role":81,"phone":37,"phoneExt":37,"email":37},{"name":103,"role":68,"phone":37,"phoneExt":37,"email":37},"Blanca Gil Ibañez, PhD",{"facility":105,"status":37,"city":106,"state":107,"zip":108,"country":54,"countryCode":55,"cosmosGeoPoint":109,"geoPoint":113,"contacts":114},"Hospital Universitario Navarra","Pamplona","Navarre","31008",{"type":57,"coordinates":110},[111,112],-1.64323,42.81687,{"lat":112,"lon":111},[115,119,120],{"name":116,"role":41,"phone":117,"phoneExt":37,"email":118},"Juan Carlos Muruzabal, PhD","0034 848422222","jc.muruzabal.torquemada@navarra.es",{"name":116,"role":81,"phone":37,"phoneExt":37,"email":37},{"name":121,"role":68,"phone":37,"phoneExt":37,"email":37},"Amelia Marí",{"facility":123,"status":37,"city":124,"state":124,"zip":125,"country":54,"countryCode":55,"cosmosGeoPoint":126,"geoPoint":130,"contacts":131},"Hospital Universitario y Politécnico La Fe","Valencia","46026",{"type":57,"coordinates":127},[128,129],-0.37966,39.47391,{"lat":129,"lon":128},[132,136,137],{"name":133,"role":41,"phone":134,"phoneExt":37,"email":135},"Santiago Domingo Del Pozo, PhD","0034 961244000","santiago.domingo.delpozo@gmail.com",{"name":133,"role":81,"phone":37,"phoneExt":37,"email":37},{"name":138,"role":68,"phone":37,"phoneExt":37,"email":37},"Óscar Díaz Cambronero, PhD",{"type":81,"investigatorFullName":140,"investigatorTitle":141,"investigatorAffiliation":5,"oldNameTitle":37,"oldOrganization":37},"Berta Diaz-Feijoo","Head of Gynecology Oncology",[143],{"name":144,"class":145},"Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Spain","UNKNOWN","100632140","extended-versus-short-prehabilitation-programme-for-patients-with-advanced-ovarian-cancer-undergoing-major-surgery-100632140",false,"NCT07509814","Extended Versus Short Prehabilitation Programme for Patients With Advanced Ovarian Cancer Undergoing Major Surgery","Efficacy of an Extended Prehabilitation Program Versus Standard in Patients With Advanced Ovarian Cancer Within ERAS Protocols","SOPHIE II","Inclusion Criteria:\n\n* Patients diagnosed with advanced ovarian cancer (FIGO III and IV)\n* Clinical indication of neoadjuvant chemotherapy followed by cytoreductive surgery\n* No contraindications for exercise training\n* Give written consent to participate\n\nExclusion Criteria:\n\n* Patients diagnosed with advanced ovarian cancer scheduled for cytoredutive surgery followed by chemotherapy (no neoadjuvant)\n* Patients with deteriorated functional state (ECOG ≥2) or those with contraindication to exercise training (severe or unstable cardiorespiratory, metabolic, musculoskeletal or neurological conditions)","FEMALE","18 Years",{"count":157,"type":158},225,"ESTIMATED","INTERVENTIONAL",[161],"NA","Standard treatment for advanced ovarian cancer includes a combination of cytotoxic chemotherapy and citorreductive surgery. During neo-adjuvant administration of chemotherapy, many patients experience a decline in their functional capacity, leading to an increased risk of postoperative complication as a combination of potential malnutrition, decreased physical activity levels and increased anxiety. Prehabilitation programs conducted within Enhanced Rescovery After Surgery (ERAS) pathways have shown to reduce postoperative complications and length of hospital stay in a diverse group of cancer surgeries and, according to some preliminary evidence, can also increase tumour response in patients receiving neoadjuvant chemotherapy. The aim of this study is to compare two modalities of prehabilitation (extended versus estandard) on postoperative complications and response to neoadjuvant chemotherapy. A total of 225 patients will be randomized in a 2:1 ratio to extended prehabilitation (initiated at the onset of neoadjuvant therapy) or standard prehabilitation (initiated after the course of neoadjuvant therapy is completed). In both groups the prehabilitation program will be delivered in the same manner, including supervised (virtual or facility-based) exercise training, nutritional optimization and psychological support and will be supported by a digital platform.",[164],"Ovarian Cancer With Peritoneal Carcinosis",[166,167,168,169,170],"Prehabilitation","Neoadjuvant Therapy","Interval surgery","Postoperative Complications","Treatment response","NOT_YET_RECRUITING","2026-03-29",{"date":174,"type":175},"2026-04-03","ACTUAL",{"date":177,"type":158},"2026-04-01",{"date":179,"type":158},"2028-12-31",{"name":5,"class":6},5]