[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100530941":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":35,"locations":44,"responsibleParty":79,"collaborators":82,"id":85,"slug":86,"hasResults":87,"nctId":88,"briefTitle":89,"officialTitle":90,"acronym":25,"eligibilityCriteria":91,"healthyVolunteers":87,"sex":92,"minAge":93,"maxAge":25,"enrollmentInfo":94,"targetDuration":25,"studyType":97,"phases":98,"briefSummary":100,"conditions":101,"keywords":25,"overallStatus":103,"whyStopped":25,"lastUpdateSubmitDate":104,"lastUpdatePostDateStruct":105,"startDateStruct":108,"completionDateStruct":110,"leadSponsor":112,"locationsCount":113},{"fullName":5,"class":6},"University College Hospital, Ibadan","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"antibiotic-coated plate","EXPERIMENTAL","participants will receive antibiotic-coated plate for treatment of their type III open long bone fractures",[13],"Procedure: antibiotic-coated plate",{"label":15,"type":16,"description":17,"interventionNames":18},"External Fixator","ACTIVE_COMPARATOR","participants will receive external fixator for treatment of their type III open long bone fractures",[19],"Procedure: external fixator",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","A plate for fixing long bone fractures is coated with antibiotics cement prepared in theatre",[9],null,{"type":22,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"external fixator","external fixators are applied to participants with severe long bone fractures",[15],[31],{"name":32,"affiliation":33,"role":34},"Oluwasegun Aremu","University College Hospital, Ibadan, Nigeria","PRINCIPAL_INVESTIGATOR",[36,40],{"name":32,"role":37,"phone":38,"phoneExt":25,"email":39},"CONTACT","+2347069414622","segunaremu2k3@yahoo.com",{"name":41,"role":37,"phone":42,"phoneExt":25,"email":43},"Olugboyega Oyewole","+2348023657211","dokitagboe@gmail.com",[45,58],{"facility":46,"status":25,"city":47,"state":48,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":25},"Federal Medical Centre, Owo","Owo","Ondo State","+234","Nigeria","NG",{"type":53,"coordinates":54},"Point",[55,56],5.58681,7.1962,{"lat":56,"lon":55},{"facility":59,"status":25,"city":60,"state":61,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":62,"geoPoint":66,"contacts":67},"Univeristy College Hospital, Ibadan, Nigeria","Ibadan","Oyo State",{"type":53,"coordinates":63},[64,65],3.90591,7.37756,{"lat":65,"lon":64},[68,69,70,71,73,75,77],{"name":32,"role":37,"phone":38,"phoneExt":25,"email":39},{"name":41,"role":37,"phone":42,"phoneExt":25,"email":43},{"name":32,"role":34,"phone":25,"phoneExt":25,"email":25},{"name":41,"role":72,"phone":25,"phoneExt":25,"email":25},"SUB_INVESTIGATOR",{"name":74,"role":72,"phone":25,"phoneExt":25,"email":25},"Olayinka Olawoye",{"name":76,"role":72,"phone":25,"phoneExt":25,"email":25},"Olusegun Ogunlage",{"name":78,"role":72,"phone":25,"phoneExt":25,"email":25},"Adeleke Ifesanya",{"type":80,"investigatorFullName":32,"investigatorTitle":81,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"SPONSOR_INVESTIGATOR","DR",[83],{"name":84,"class":6},"Orthopaedic Trauma Association","100530941","external-fixator-or-antibiotic-coated-plate-in-severe-open-long-bone-fractures-100530941",false,"NCT06193330","External Fixator or Antibiotic-coated Plate in Severe Open Long Bone Fractures","Use of Antibiotics-cement Coated Plate in the Treatment of Gustilo-Anderson Type III Long Bone Fractures in Low- and Middle-income Countries vs External Fixation: A Multi-centre Randomized Control Trial","Inclusion Criteria:\n\n* Age ≥ 18yrs,\n* Gustilo-Anderson IIIA and IIIB open fractures,\n* involvement of any long bone fractures that can be fixed with either plate or uniplanar external fixation,\n* wound can be closed primarily, with skin graft or flap, or can heal secondarily\n\nExclusion Criteria:\n\n* Patients with traumatic brain injury,\n* spinal cord injury,\n* severe burns,\n\n  * 1 long bone fractures,\n* refusal to consent,\n* history of allergies to ceftriaxone or sulbactam,\n* fractures associated with vascular injury\n* and non-compliance with follow-up.","ALL","18 Years",{"count":95,"type":96},178,"ESTIMATED","INTERVENTIONAL",[99],"NA","The purpose of the study is to assess whether infection rate is reduced with use of antibiotic-coated plate in severe open tibial fractures compare to use of external fixators",[102],"Fracture Related Infection","NOT_YET_RECRUITING","2023-12-21",{"date":106,"type":107},"2024-01-05","ACTUAL",{"date":109,"type":96},"2024-01-01",{"date":111,"type":96},"2026-12-31",{"name":32,"class":6},2]